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Eugene Braunwald
Researcher at Brigham and Women's Hospital
Publications - 1758
Citations - 278949
Eugene Braunwald is an academic researcher from Brigham and Women's Hospital. The author has contributed to research in topics: Myocardial infarction & TIMI. The author has an hindex of 230, co-authored 1711 publications receiving 264576 citations. Previous affiliations of Eugene Braunwald include Boston University & University of California, San Francisco.
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Effects of mitral-valve replacement on the pulmonary vascular dynamics of patients with pulmonary hypertension.
TL;DR: In many patients the elevation of pulmonary vascular resistance is extreme and constitutes the major hemodynamic burden faced by the right ventricle, and under these circumstances the secondary changes in the pulmonary vascular bed become primarily responsible for many of the clinical findings, including ventricular failure.
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The reduction of infarct size--an idea whose time (for testing) has come.
Eugene Braunwald,Peter R. Maroko +1 more
TL;DR: Technological developments during subsequent decades allowed a systematic reexamination of this problem in the mid-1950s, resulting in more precise elucidation of the role of intraventricular tension, myocardial fiber shortening, contraction frequency, and external cardiac work in regulating the heart's oxygen needs.
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Left Ventricular Performance Following Correction of Free Aortic Regurgitation
TL;DR: A fixed abnormality in diastolic LV pressure-volume characteristics, determined from preoperative and postoperative measurements of pressure and radius during diastole, had occurred in patients with depressed myocardial function, suggesting reversal of stress relaxation, or creep, following relief of volume overload.
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Association of white blood cell count with increased mortality in acute myocardial infarction and unstable angina pectoris
TL;DR: It is observed in a study of 7,651 patients with acute coronary syndromes that a white blood cell count of > 10,000 was associated with increased 30-day and 10-month mortality.
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Differential expression of cardiac biomarkers by gender in patients with unstable angina/non-ST-elevation myocardial infarction: a TACTICS-TIMI 18 (Treat Angina with Aggrastat and determine Cost of Therapy with an Invasive or Conservative Strategy-Thrombolysis In Myocardial Infarction 18) substudy.
Stephen D. Wiviott,Christopher P. Cannon,David A. Morrow,Sabina A. Murphy,C. Michael Gibson,Carolyn H. McCabe,Marc S. Sabatine,Nader Rifai,Robert P. Giugliano,Peter M. DiBattiste,Laura A. Demopoulos,Elliott M. Antman,Eugene Braunwald +12 more
TL;DR: In patients with UA/NSTEMI, there was a different pattern of presenting biomarkers, whereas women were more likely to have elevated C-reactive protein and brain natriuretic peptide, which suggests that a multimarker approach may aid the initial risk assessment of UA-N STEMI, especially in women.