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Eva Tolosa
Researcher at University of Hamburg
Publications - 156
Citations - 9376
Eva Tolosa is an academic researcher from University of Hamburg. The author has contributed to research in topics: T cell & Immune system. The author has an hindex of 39, co-authored 143 publications receiving 8148 citations. Previous affiliations of Eva Tolosa include University of Tübingen & Autonomous University of Barcelona.
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Journal ArticleDOI
Clinical research criteria for the diagnosis of progressive supranuclear palsy (Steele-Richardson-Olszewski syndrome) Report of the NINDS-SPSP International Workshop*
Irene Litvan,Yves Agid,Donald B. Calne,G. Campbell,Bruno Dubois,Roger C. Duvoisin,Christopher G. Goetz,Lawrence I. Golbe,Jordan Grafman,John H. Growdon,Mark Hallett,Joseph Jankovic,Niall Quinn,Eva Tolosa,David S. Zee +14 more
TL;DR: Criteria that support the diagnosis of progressive supranuclear palsy, and that exclude diseases often confused with PSP, are presented.
Journal ArticleDOI
Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke
Mathias Gelderblom,Frank Leypoldt,Karin Steinbach,Doerthe Behrens,Chi-Un Choe,Dominic A. Siler,Thiruma V. Arumugam,Ellen Orthey,Christian Gerloff,Eva Tolosa,Tim Magnus +10 more
TL;DR: The peculiar activation pattern and massive increase of antigen-presenting cells in temporal conjunction with regulatory cells might provide additional insight into poststroke immune regulation.
Journal ArticleDOI
Phenotypical and functional characterization of T helper 17 cells in multiple sclerosis
TL;DR: The frequency and phenotype of Th17 cells in the cerebrospinal fluid and peripheral blood of multiple sclerosis patients are analysed to suggest that Th 17 cells display a high pathogenic potential and may constitute a relevant pathogenic subset in multiple sclerosis.
Journal ArticleDOI
Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke.
Mathias Gelderblom,Anna Weymar,Christian Bernreuther,Joachim Velden,Priyadharshini Arunachalam,Karin Steinbach,Ellen Orthey,Thiruma V. Arumugam,Frank Leypoldt,Olga Simova,Vivien Thom,Manuel A. Friese,Immo Prinz,Christoph Hölscher,Markus Glatzel,Thomas Korn,Christian Gerloff,Eva Tolosa,Tim Magnus +18 more
TL;DR: It is proposed that selective targeting of IL-17A signaling might provide a new therapeutic option for the treatment of stroke, and this aspect of the inflammatory cascade is also relevant in the human brain.
Journal ArticleDOI
Toll-Like Receptor Engagement Enhances the Immunosuppressive Properties of Human Bone Marrow-Derived Mesenchymal Stem Cells by Inducing Indoleamine-2,3-dioxygenase-1 via Interferon-β and Protein Kinase R
Christiane A. Opitz,Christiane A. Opitz,Ulrike M. Litzenburger,Christian Lutz,Tobias V. Lanz,Isabel Tritschler,Alexandra Köppel,Eva Tolosa,Maik Hoberg,Jan Anderl,Wilhelm K. Aicher,Michael Weller,Michael Weller,Wolfgang Wick,Wolfgang Wick,Michael Platten,Michael Platten +16 more
TL;DR: A new role for TLR is defined in MSC immunobiology, which is to augment the immunosuppressive properties of MSC in the absence of IFN‐γ rather than inducing proinflammatory immune response pathways.