F
F. Ivy Carroll
Researcher at Research Triangle Park
Publications - 301
Citations - 11139
F. Ivy Carroll is an academic researcher from Research Triangle Park. The author has contributed to research in topics: Nicotinic agonist & Dopamine transporter. The author has an hindex of 52, co-authored 301 publications receiving 10411 citations. Previous affiliations of F. Ivy Carroll include RTI International & St. Joseph's Hospital and Medical Center.
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Journal ArticleDOI
Synthesis, nicotinic acetylcholine receptor binding, antinociceptive and seizure properties of methyllycaconitine analogs.
F. Ivy Carroll,Wei Ma,Hernán A. Navarro,Philip Abraham,Scott A. Wolckenhauer,M. I. Damaj,Billy R. Martin +6 more
TL;DR: Since MLA has been reported to show neuroprotection against beta-amyloid(1-42), these new analogs which have high alpha7 nAChR affinity and good selectivity relative to alpha,beta nA ChRs will be useful biological tools for studying the effects ofalpha7 n AChR antagonist and neuroprotection.
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N-substituted cis-4a-(3-hydroxyphenyl)-8a-methyloctahydroisoquinolines are opioid receptor pure antagonists.
F. Ivy Carroll,Sachin Chaudhari,James B. Thomas,S. Wayne Mascarella,Kenneth M. Gigstad,Jeffrey R. Deschamps,Hernán A. Navarro +6 more
TL;DR: Evaluation of 6a-g in the [(35)S]GTP-gamma-S in vitro functional assay showed that they were opioid receptor pure antagonists, possessing the best combination of kappa potency and selectivity.
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Interaction of cocaine and dopamine transporter inhibitors on behavior and neurochemistry in monkeys
TL;DR: There was little evidence of additivity on behavioral or neurochemical measures when cocaine was administered in combination with behavioral-stimulant doses of the DAT inhibitors, indicating that the pharmacological profile of DAT inhibitor may be influenced by actions at multiple monoamine transporters.
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Synthesis, nicotinic acetylcholine receptor binding, and pharmacological properties of 3′-(substituted phenyl)deschloroepibatidine analogs
F. Ivy Carroll,Yasuno Yokota,Wei Ma,Jeffrey R. Lee,Lawrence E. Brieaddy,Jason P. Burgess,Hernán A. Navarro,M. I. Damaj,Billy R. Martin +8 more
TL;DR: 5a-k are potent antagonists in nicotine-induced antinociception in the tail-flick test, but weaker than the corresponding 2'-fluoro-3'-(substituted phenyl)deschloroepibatidines.
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Pituitary Adenylate Cyclase-Activating Polypeptide Disrupts Motivation, Social Interaction, and Attention in Male Sprague Dawley Rats.
TL;DR: The findings suggest that PACAP affects numerous domains often dysregulated in mood and anxiety disorders, but that individual signs depend on brain substrates that are at least partially independent.