Frank M. Sacks

TL;DR: In this article, the effect of five years of pravastatin therapy on coronary events was investigated in the Cholesterol And Recurrent Events (CARE) cohort, and it was found that the odds ratios for the primary end point were not significantly different from unity for the three genetic subgroups after 5 years of placebo treatment, and both nonfatal myocardial infarction and deaths from coronary heart disease were reduced to the same extent in all three genotypes.

TL;DR: It appears that neither the amount of protein in the diet nor whether the protein comes from animal or vegetable sources has an important effect on plasma LDL and HDL levels in humans when consumed in physiologic amounts.

TL;DR: Abstract “hypertriglyceridemia represents a growing problem in the general population and should be considered a priority for further research.”

TL;DR: Plant-based diets, especially when rich in healthier plant foods, are associated with less weight gain over 4-y intervals, which supports current recommendations to increase intake of healthy plant Foods, and reducing intake of less-healthy plant foods and animal foods, for improved health outcomes.

TL;DR: There is a consistency developing that maximal statin therapy produces a superior result on measurements of atherosclerosis in clinically important sites, and it now seems true that statins produce similar relative risk reduction across a wide variety of patient types and clinical presentations.