F
Frank M. Sacks
Researcher at Harvard University
Publications - 520
Citations - 86842
Frank M. Sacks is an academic researcher from Harvard University. The author has contributed to research in topics: Cholesterol & Weight loss. The author has an hindex of 120, co-authored 490 publications receiving 80422 citations. Previous affiliations of Frank M. Sacks include Erasmus University Rotterdam & University of Texas Health Science Center at Houston.
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Journal ArticleDOI
Macronutrient Intake-Associated FGF21 Genotype Modifies Effects of Weight-Loss Diets on 2-Year Changes of Central Adiposity and Body Composition: The POUNDS Lost Trial.
Yoriko Heianza,Wenjie Ma,Tao Huang,Tiange Wang,Yan Zheng,Steven R. Smith,George A. Bray,Frank M. Sacks,Lu Qi +8 more
TL;DR: A low-calorie, high-carbohydrate/low-fat diet was beneficial for overweight or obese individuals carrying the carbohydrate intake–decreasing allele of the FGF21 variant to improve body composition and abdominal obesity.
Journal ArticleDOI
Variants in glucose- and circadian rhythm–related genes affect the response of energy expenditure to weight-loss diets: the POUNDS LOST Trial
TL;DR: The data indicate that variants in the circadian-related genes CRY2 and MTNR1B may affect long-term changes in energy expenditure, and dietary fat intake may modify the genetic effects.
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Apolipoprotein E in VLDL and LDL With Apolipoprotein C‐III is Associated With a Lower Risk of Coronary Heart Disease
Carlos O. Mendivil,Eric B. Rimm,Eric B. Rimm,Jeremy D. Furtado,Frank M. Sacks,Frank M. Sacks +5 more
TL;DR: An increased apoE content in VLDL and LDL with apoC‐III was associated with a lower risk of CHD, independent of traditional CHD risk factors and of C‐reactive protein.
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Differential Metabolism of Human VLDL According to Content of ApoE and ApoC-III
TL;DR: Metabolism of human VLDL particles is influenced by their content of apoE, further modulated by the coexistence of apolipoprotein C-III, and the rate constant for lipolysis of dense V LDL to IDL was greater for E− than for E+, and the rates constant for clearance from plasma were greater for dense VLDl E+ than forE−.
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The effects of dietary patterns on urinary albumin excretion: results of the Dietary Approaches to Stop Hypertension (DASH) Trial.
David R. Jacobs,David R. Jacobs,Myron D. Gross,Lyn M. Steffen,Michael W. Steffes,Xinhua Yu,Laura P. Svetkey,Lawrence J. Appel,William M. Vollmer,George A. Bray,Thomas Burton Moore,Paul R. Conlin,Frank M. Sacks +12 more
TL;DR: The decrease in AER after 8 weeks occurred in only those with high-normal baseline AER in the FV diet, in a pattern distinct from the blood pressure decrease, and the DASH diet did not increase AER despite a 3% increase in energy from protein.