F
Frank M. Sacks
Researcher at Harvard University
Publications - 520
Citations - 86842
Frank M. Sacks is an academic researcher from Harvard University. The author has contributed to research in topics: Cholesterol & Weight loss. The author has an hindex of 120, co-authored 490 publications receiving 80422 citations. Previous affiliations of Frank M. Sacks include Erasmus University Rotterdam & University of Texas Health Science Center at Houston.
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Nicotinic acid: a review of its clinical use in the treatment of lipid disorders.
TL;DR: The beneficial effects, taken together with the low cost of nicotinic acid therapy and the relative freedom from serious side effects, have made nicotinIC acid the agent of choice for the treatment of many patients with hyperlipidemia.
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Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study: Rationale, design and baseline characteristics of a randomized control trial of the MIND diet on cognitive decline.
Xiaoran Liu,Martha Clare Morris,Klodian Dhana,Jennifer Ventrelle,Kathleen Johnson,Louise M. Bishop,Chiquia S. Hollings,Adrianna Boulin,Nancy Laranjo,Benjamin J. Stubbs,Xavier Reilly,Vincent J. Carey,Yamin Wang,Jeremy D. Furtado,Santica M. Marcovina,Christy Tangney,Neelum T. Aggarwal,Konstantinos Arfanakis,Frank M. Sacks,Lisa L. Barnes +19 more
TL;DR: The Mediterranean-DASH Intervention for Neurodegenerative Delay (MIND) study as discussed by the authors is a 3-year, multicenter, randomized controlled trial to test the effects of the MIND diet on cognitive function in 604 individuals at risk for Alzheimer's dementia.
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CETP genotype and changes in lipid levels in response to weight-loss diet intervention in the POUNDS LOST and DIRECT randomized trials
Qibin Qi,Qibin Qi,Ronen Durst,Dan Schwarzfuchs,Eran Leitersdorf,Shoshi Shpitzen,Yanping Li,Hongyu Wu,Catherine M. Champagne,Frank B. Hu,Frank B. Hu,Meir J. Stampfer,Meir J. Stampfer,George A. Bray,Frank M. Sacks,Iris Shai,Lu Qi,Lu Qi +17 more
TL;DR: In this article, the effect of cholesteryl ester transfer protein (CETP) genetic variation may modify the effects of weight-loss diets varying in fat content on changes in lipid levels.
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Sex hormones, lipoproteins, and vascular reactivity.
TL;DR: The HDL-raising effect of estrogen replacement is mediated by an increase in HDL-apolipoprotein A-l production and not by a decrease in the clearance rate, and large-scale clinical trials have shown that medroxyprogesterone acetate removes most of the HDL- raising effects of concomitant estrogen treatment.
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Genome-Wide Study of Gene Variants Associated with Differential Cardiovascular Event Reduction by Pravastatin Therapy
Dov Shiffman,Stella Trompet,Judy Z. Louie,Charles M. Rowland,Joseph J. Catanese,Olga Iakoubova,Todd G. Kirchgessner,Rudi G. J. Westendorp,Anton J. M. de Craen,P. Eline Slagboom,Brendan M. Buckley,David J. Stott,Naveed Sattar,James J. Devlin,Chris J. Packard,Ian Ford,Frank M. Sacks,J. Wouter Jukema +17 more
TL;DR: It is found that one of these SNPs (rs13279522) was associated with differential CHD event reduction by pravastatin therapy in all 3 studies: P = 0.002 in CARE, P’s’=’0.01 in WOSCOPS, and P”=”0.001 in PROSPER/PHASE.