F
Frédéric Leprêtre
Researcher at university of lille
Publications - 50
Citations - 3198
Frédéric Leprêtre is an academic researcher from university of lille. The author has contributed to research in topics: Single-nucleotide polymorphism & Adiponectin. The author has an hindex of 23, co-authored 46 publications receiving 2977 citations. Previous affiliations of Frédéric Leprêtre include Pasteur Institute & Lille University of Science and Technology.
Papers
More filters
Journal ArticleDOI
Genomewide Search for Type 2 Diabetes–Susceptibility Genes in French Whites: Evidence for a Novel Susceptibility Locus for Early-Onset Diabetes on Chromosome 3q27-qter and Independent Replication of a Type 2–Diabetes Locus on Chromosome 1q21–q24
Nathalie Vionnet,El Habib Hani,Sophie Dupont,Sophie Gallina,Stephan Francke,Sébastien Dotte,Frédérique De Matos,Emmanuelle Durand,Frédéric Leprêtre,Cécile Lecoeur,Philippe Gallina,Lirije Zekiri,Christian Dina,Philippe Froguel +13 more
TL;DR: Evidence for a novel susceptibility locus for type 2 diabetes in French whites on chromosome 3q27-qter is shown and the previously reported diabetes-susceptibility locus on chromosome 1q21-q24 is confirmed.
Journal ArticleDOI
Single-nucleotide polymorphism haplotypes in the both proximal promoter and exon 3 of the APM1 gene modulate adipocyte-secreted adiponectin hormone levels and contribute to the genetic risk for type 2 diabetes in French Caucasians
Francis Vasseur,Nicole Helbecque,Christian Dina,Stéphane Lobbens,Valérie Delannoy,Stéphane Gaget,Philippe Boutin,Martine Vaxillaire,Frédéric Leprêtre,Sophie Dupont,Kazuo Hara,Karine Clément,Bernard Bihain,Takashi Kadowaki,Philippe Froguel +14 more
TL;DR: The results suggest that an at-risk haplotype of common variants located in the promoter and rare mutations in exon 3 contribute to the variation of the adipocyte-secreted adiponectin hormone level, and may be part of the genetic determinants for T2D in the French Caucasian population.
Journal ArticleDOI
Translation initiator EIF4G1 mutations in familial Parkinson disease
Marie-Christine Chartier-Harlin,Marie-Christine Chartier-Harlin,Justus C. Dachsel,Carles Vilariño-Güell,Sarah Lincoln,Frédéric Leprêtre,Frédéric Leprêtre,Mary M. Hulihan,Jennifer M. Kachergus,Austen J. Milnerwood,Lucia Tapia,Mee Sook Song,Emilie Le Rhun,Eugénie Mutez,Eugénie Mutez,Lydie Larvor,Lydie Larvor,A. Duflot,A. Duflot,Christel Vanbesien-Mailliot,Christel Vanbesien-Mailliot,Alexandre Kreisler,Alexandre Kreisler,Owen A. Ross,Kenya Nishioka,Alexandra I. Soto-Ortolaza,Stephanie A. Cobb,Heather L. Melrose,Bahareh Behrouz,Brett H. Keeling,Justin A. Bacon,Emna Hentati,Lindsey N. Williams,Akiko Yanagiya,Nahum Sonenberg,Paul J. Lockhart,Abba C. Zubair,Ryan J. Uitti,Jan O. Aasly,Anna Krygowska-Wajs,Grzegorz Opala,Zbigniew K. Wszolek,Roberta Frigerio,Demetrius M. Maraganore,David Gosal,Timothy Lynch,Michael Hutchinson,Anna Rita Bentivoglio,Enza Maria Valente,Enza Maria Valente,William C. Nichols,Nathan Pankratz,Tatiana Foroud,Rachel A. Gibson,Fayçal Hentati,Dennis W. Dickson,Alain Destée,Alain Destée,Matthew J. Farrer,Matthew J. Farrer +59 more
TL;DR: Genome-wide analysis of a multi-incident family with autosomal-dominant parkinsonism has implicated a locus on chromosomal region 3q26-q28 and highlighted a convergent pathway for monogenic, toxin and perhaps virally-induced Parkinson disease.
Journal ArticleDOI
A genome-wide scan for coronary heart disease suggests in Indo-Mauritians a susceptibility locus on chromosome 16p13 and replicates linkage with the metabolic syndrome on 3q27.
Stephan Francke,Meera Manraj,Corinne Lacquemant,Cécile Lecoeur,Frédéric Leprêtre,Philippe Passa,Annick Hebe,Laetitia Corset,Solange Lee Kwai Yan,Saida Lahmidi,Sarojini Jankee,Teman K. Gunness,Uday S. Ramjuttun,Vinod Balgobin,Christian Dina,Philippe Froguel +15 more
TL;DR: The results show the first evidence for susceptibility loci that predispose to CHD, T2DM and HBP in the context of the metabolic syndrome.
Journal ArticleDOI
Correction: Corrigendum: Polymorphisms in the Mannose-Binding Lectin Gene are Associated with Defective Mannose-Binding Lectin Functional Activity in Crohn’s Disease Patients
Laura Choteau,Francis Vasseur,Frédéric Leprêtre,Martin Figeac,C. Gower-Rousseau,Laurent Dubuquoy,Daniel Poulain,Jean-Frederic Colombel,Boualem Sendid,Samir Jawhara +9 more
TL;DR: Scientific Reports 6: Article number: 29636; published online: 12 July 2016; updated: 16 September 2016 .