G
G.A.P. Cirrone
Researcher at Istituto Nazionale di Fisica Nucleare
Publications - 278
Citations - 12559
G.A.P. Cirrone is an academic researcher from Istituto Nazionale di Fisica Nucleare. The author has contributed to research in topics: Proton therapy & Monte Carlo method. The author has an hindex of 31, co-authored 258 publications receiving 10567 citations. Previous affiliations of G.A.P. Cirrone include University of Catania & ASTRON.
Papers
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Journal ArticleDOI
A goodness-of-fit statistical toolkit
G.A.P. Cirrone,S. Donadio,Susanna Guatelli,A. Mantero,B. Mascialino,S. Parlati,Maria Grazia Pia,Andreas Pfeiffer,Alberto Ribon,P. Viarengo +9 more
TL;DR: The statistical details of the algorithms and the computational features of the Toolkit, an object-oriented software Toolkit for statistical data analysis, are described and the results obtained reproducing a couple of Goodness-of-Fit testing examples of relevance in statistics literature are described.
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Diamond detector versus silicon diode and ion chamber in photon beams of different energy and field size
TL;DR: The results obtained confirm that ion chamber is not a suitable detector when high spatial resolution is required and the small differences in the studied parameters do not lead to a significant advantage in the use of diamond detector for routine clinical dosimetry.
Journal ArticleDOI
An investigation of the operating characteristics of two PTW diamond detectors in photon and electron beams.
C. De Angelis,Sandro Onori,M. Pacilio,G.A.P. Cirrone,Giacomo Cuttone,L. Raffaele,Marta Bucciolini,S. Mazzocchi +7 more
TL;DR: The dosimetric properties of two PTW Riga diamond detectors type 60003 were studied in high-energy photon and electron therapy beam and the necessity to characterize each diamond detector individually was addressed.
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Implementation of a new Monte Carlo-GEANT4 Simulation tool for the development of a proton therapy beam line and verification of the related dose distributions
G.A.P. Cirrone,Giacomo Cuttone,Susanna Guatelli,S. Lo Nigro,B. Mascialino,Maria Grazia Pia,Luigi Raffaele,Giorgio Ivan Russo,Maria Gabriella Sabini +8 more
TL;DR: In this paper, the Monte Carlo simulation tool GEANT4 was used to simulate the hadron-therapy beam line of the Centro di AdroTerapia ed Applicazioni Nucleari Avanzate (CATANA) center.
Journal ArticleDOI
Cellular and molecular effects of protons: apoptosis induction and potential implications for cancer therapy.
C. Di Pietro,Salvatore Piro,Giovanni Tabbì,Maria Alessandra Ragusa,V. Di Pietro,V. Zimmitti,F. Cuda,M. Anello,Ugo Consoli,Elisa Trovato Salinaro,Massimo Caruso,Carlo Vancheri,Nunzio Crimi,Maria Gabriella Sabini,G.A.P. Cirrone,Luigi Raffaele,G. Privitera,Alfredo Pulvirenti,Rosalba Giugno,Alfredo Ferro,Giacomo Cuttone,S. Lo Nigro,Roberto Purrello,Francesco Purrello,Michele Purrello +24 more
TL;DR: D dose-response and time-course experiments with photons demonstrated that they induce apoptosis in a significantly lower number of cells and in a temporally delayed manner, which could be useful for improving current hadrontherapy protocols.