G
Gavin Maxwell
Researcher at Unilever
Publications - 33
Citations - 1578
Gavin Maxwell is an academic researcher from Unilever. The author has contributed to research in topics: Local lymph node assay & Risk assessment. The author has an hindex of 13, co-authored 30 publications receiving 1345 citations. Previous affiliations of Gavin Maxwell include Syngenta.
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Journal ArticleDOI
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
Sarah Adler,David A. Basketter,Stuart Creton,Olavi Pelkonen,Jan van Benthem,Valérie Zuang,Klaus Ejner Andersen,Alexandre Angers-Loustau,Aynur O. Aptula,Anna Bal-Price,Emilio Benfenati,Ulrike Bernauer,J.G.M. Bessems,Frédéric Y. Bois,Alan R. Boobis,Esther Brandon,Susanne Bremer,Thomas H. Broschard,Silvia Casati,Sandra Coecke,Raffaella Corvi,Mark T. D. Cronin,George P. Daston,Wolfgang Dekant,Susan P. Felter,Elise Grignard,Ursula Gundert-Remy,Tuula Heinonen,Ian Kimber,Jos C. S. Kleinjans,Hannu Komulainen,Reinhard Kreiling,Joachim Kreysa,Sofia B. Leite,George Loizou,Gavin Maxwell,Paolo Mazzatorta,Sharon Munn,Stefan Pfuhler,Pascal Phrakonkham,Aldert H. Piersma,Albrecht Poth,Pilar Prieto,Guillermo Repetto,Vera Rogiers,Greet Schoeters,Michael Schwarz,Rositsa Serafimova,Hanna Tähti,Emanuela Testai,Joost H.M. van Delft,Henk Van Loveren,Mathieu Vinken,Andrew Worth,Jose-Manuel Zaldivar +54 more
TL;DR: In this paper, Adler et al. present a survey of the authors' work in the field of bioinformatics, including the following authors:Sarah AdlerDavid BasketterStuart CretonOlavi PelkonenJan van BenthemValerie Zuang • Klaus Ejner AndersenAlexandre Angers-LoustauAynur AptulaAnna Bal-PriceEmilio Benfenati • Ulrike BernauerJos BessemsFrederic Y. BoisAlan BoobisEsther BrandonSusanne Bremer • Thomas
Journal ArticleDOI
A roadmap for the development of alternative (non-animal) methods for systemic toxicity testing.
David A. Basketter,Harvey J. Clewell,Ian Kimber,Annamaria Rossi,Bas J. Blaauboer,Robert Burrier,Mardas Daneshian,Chantra Eskes,Alan M. Goldberg,Nina Hasiwa,Sebastian Hoffmann,Joanna Jaworska,Thomas B. Knudsen,Robert Landsiedel,Marcel Leist,Paul A. Locke,Gavin Maxwell,James M. McKim,Emily A. McVey,Gladys Ouedraogo,Grace Patlewicz,Olavi Pelkonen,Erwin Ludo Roggen,Costanza Rovida,Irmela Ruhdel,Michael Schwarz,Andreas Schepky,Greet Schoeters,Nigel Skinner,Kerstin Trentz,Marian Turner,Philippe Vanparys,James D. Yager,Joanne Zurlo,Thomas Hartung +34 more
TL;DR: In this paper, the authors present a roadmap for how to overcome the acknowledged scientific gaps for the full replacement of systemic toxicity testing using animals, which is a major concern for the current state of the art.
Journal ArticleDOI
How Adverse Outcome Pathways Can Aid the Development and Use of Computational Prediction Models for Regulatory Toxicology.
Clemens Wittwehr,Hristo Aladjov,Gerald T. Ankley,Hugh J. Byrne,Joop de Knecht,Elmar Heinzle,Günter Klambauer,Brigitte Landesmann,Mirjam Luijten,Cameron MacKay,Gavin Maxwell,M.E. Bette Meek,Alicia Paini,Edward J. Perkins,Tomasz Sobanski,Daniel L. Villeneuve,Katrina M. Waters,Maurice Whelan +17 more
TL;DR: It is argued that the systematic organization of knowledge into AOP frameworks can inform and help direct the design and development of computational prediction models that can further enhance the utility of mechanistic and in silico data for chemical safety assessment.
Journal ArticleDOI
Systematic evaluation of non-animal test methods for skin sensitisation safety assessment
Kerstin Reisinger,Sebastian Hoffmann,Nathalie Alépée,Takao Ashikaga,João Barroso,Cliff Elcombe,Nicola Gellatly,Valentina Galbiati,Susan Gibbs,Hervé Groux,Jalila Hibatallah,Donald Keller,Petra S. Kern,Martina Klaric,Susanne N. Kolle,Jochen Kuehnl,Nathalie Lambrechts,Malin Lindstedt,Marion Millet,Silvia Martinozzi-Teissier,Andreas Natsch,Dirk Petersohn,Ian Pike,Hitoshi Sakaguchi,Andreas Schepky,Magalie Tailhardat,Marie Templier,Erwin van Vliet,Gavin Maxwell +28 more
TL;DR: The testing strategy – combined with bioavailability and skin metabolism data and exposure consideration – is envisaged to allow establishment of a data integration approach for skin sensitisation safety assessment of cosmetic ingredients.
Journal ArticleDOI
Quantitative Characterization of the T Cell Receptor Repertoire of Naïve and Memory Subsets Using an Integrated Experimental and Computational Pipeline Which Is Robust, Economical, and Versatile.
Theres Oakes,James M. Heather,Katharine Best,Rachel Byng-Maddick,Connor Husovsky,Mazlina Ismail,Kroopa Joshi,Gavin Maxwell,Mahdad Noursadeghi,Natalie E. Riddell,Tabea Ruehl,Carolin T. Turner,Imran Uddin,Benny Chain +13 more
TL;DR: In this article, a protocol for amplifying, sequencing and analysing TCRs is described, which is robust, sensitive and versatile, and is applied to the analysis of human memory and naive subpopulations, and results in consistent measures of diversity and inequality.