H
Hannu Komulainen
Researcher at National Institutes of Health
Publications - 14
Citations - 956
Hannu Komulainen is an academic researcher from National Institutes of Health. The author has contributed to research in topics: Fura-2 & Calcium. The author has an hindex of 8, co-authored 14 publications receiving 916 citations.
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Journal ArticleDOI
Alternative (non-animal) methods for cosmetics testing: current status and future prospects—2010
Sarah Adler,David A. Basketter,Stuart Creton,Olavi Pelkonen,Jan van Benthem,Valérie Zuang,Klaus Ejner Andersen,Alexandre Angers-Loustau,Aynur O. Aptula,Anna Bal-Price,Emilio Benfenati,Ulrike Bernauer,J.G.M. Bessems,Frédéric Y. Bois,Alan R. Boobis,Esther Brandon,Susanne Bremer,Thomas H. Broschard,Silvia Casati,Sandra Coecke,Raffaella Corvi,Mark T. D. Cronin,George P. Daston,Wolfgang Dekant,Susan P. Felter,Elise Grignard,Ursula Gundert-Remy,Tuula Heinonen,Ian Kimber,Jos C. S. Kleinjans,Hannu Komulainen,Reinhard Kreiling,Joachim Kreysa,Sofia B. Leite,George Loizou,Gavin Maxwell,Paolo Mazzatorta,Sharon Munn,Stefan Pfuhler,Pascal Phrakonkham,Aldert H. Piersma,Albrecht Poth,Pilar Prieto,Guillermo Repetto,Vera Rogiers,Greet Schoeters,Michael Schwarz,Rositsa Serafimova,Hanna Tähti,Emanuela Testai,Joost H.M. van Delft,Henk Van Loveren,Mathieu Vinken,Andrew Worth,Jose-Manuel Zaldivar +54 more
TL;DR: In this paper, Adler et al. present a survey of the authors' work in the field of bioinformatics, including the following authors:Sarah AdlerDavid BasketterStuart CretonOlavi PelkonenJan van BenthemValerie Zuang • Klaus Ejner AndersenAlexandre Angers-LoustauAynur AptulaAnna Bal-PriceEmilio Benfenati • Ulrike BernauerJos BessemsFrederic Y. BoisAlan BoobisEsther BrandonSusanne Bremer • Thomas
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Increased free intrasynaptosomal Ca2+ by neurotoxic organometals: distinctive mechanisms.
TL;DR: Results indicate that neurotoxic derivatives of alkylmetals studied increase [Ca2+]i, mainly either by nonspecific increase (Met-Hg, TET) of Ca2+ leakage through the plasma membrane and/or specific interference with the mechanisms regulating Ca2- fluxes through the Plasma membrane (TEL).
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The estimation of free calcium within synaptosomes and mitochondria with fura-2; comparison to quin-2
TL;DR: Fura-2 requiring the use of two excitation wavelengths was significantly superior to the single wavelength method using quin-2, and reduced danger of erroneous readings due to synaptosomal sedimentation, photobleaching of the dye, and underestimation of intrasynptosomal calcium during correction for dye leakage by manganese entry into synaptoomes makes fura- 2 of superior utility in the determination of free intrasyndical calcium.
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Increased free intracellular Ca2+ by toxic agents: an index of potential neurotoxicity?
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Transient elevation of intrasynaptosomal free calcium by putrescine.
TL;DR: Putrescine (1 mM) added together with DFMO negated the effect of DFMO suggesting that abnormally low polyamine concentrations were the reason for the diminished K+-response.