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Panagiotis Koufargyris
Researcher at National and Kapodistrian University of Athens
Publications - 14
Citations - 2215
Panagiotis Koufargyris is an academic researcher from National and Kapodistrian University of Athens. The author has contributed to research in topics: Clinical endpoint & Lower respiratory tract infection. The author has an hindex of 4, co-authored 12 publications receiving 1259 citations.
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Journal ArticleDOI
Complex immune dysregulation in covid-19 patients with severe respiratory failure
Evangelos J. Giamarellos-Bourboulis,Mihai G. Netea,Mihai G. Netea,Nikoletta Rovina,Karolina Akinosoglou,Anastasia Antoniadou,Nikolaos Antonakos,Georgia Damoraki,Theologia Gkavogianni,Maria Evangelia Adami,Paraskevi Katsaounou,Maria Ntaganou,Magdalini Kyriakopoulou,George Dimopoulos,Ioannis Koutsodimitropoulos,Dimitrios Velissaris,Panagiotis Koufargyris,Athanassios Karageorgos,Konstantina Katrini,Vasileios Lekakis,Mihaela Lupse,Antigone Kotsaki,George Renieris,Danai Theodoulou,Vassiliki Panou,Evangelia Koukaki,Nikolaos Koulouris,Charalambos Gogos,Antonia Koutsoukou +28 more
TL;DR: In this paper, the authors found that severe respiratory failure (SRF) in COVID-19 patients is driven by a unique pattern of immune dysfunction, characterized by IL-6-mediated low HLA-DR expression and lymphopenia, associated with sustained cytokine production and hyper-inflammation.
Journal ArticleDOI
Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.
Evdoxia Kyriazopoulou,Garyfallia Poulakou,Haralampos J. Milionis,Simeon Metallidis,Georgios Adamis,Konstantinos Tsiakos,Archontoula Fragkou,Aggeliki Rapti,Christina Damoulari,Massimo Fantoni,Ioannis Kalomenidis,Georgios Chrysos,Andrea Angheben,Ilias Kainis,Zoi Alexiou,Francesco Castelli,Francesco Saverio Serino,Maria Tsilika,Petros Bakakos,Emanuele Nicastri,Vassiliki Tzavara,Evangelos Kostis,Lorenzo Dagna,Panagiotis Koufargyris,Katerina Dimakou,Spyridon Savvanis,Glykeria Tzatzagou,Maria Giovanna Chini,Giulio Cavalli,Matteo Bassetti,Konstantina Katrini,Vasileios Kotsis,George Tsoukalas,Carlo Selmi,Ioannis Bliziotis,Michael Samarkos,Michael Doumas,Sofia Ktena,Aikaterini Masgala,Ilias Papanikolaou,Maria Kosmidou,Dimitra Melia Myrodia,Aikaterini Argyraki,Chiara Simona Cardellino,Katerina Koliakou,Eleni Ioanna Katsigianni,Vassiliki Rapti,Efthymia Giannitsioti,Antonella Cingolani,Styliani Micha,Karolina Akinosoglou,Orestis Liatsis-Douvitsas,Styliani Symbardi,Nikolaos K. Gatselis,Maria Mouktaroudi,Giuseppe Ippolito,Eleni Florou,Antigone Kotsaki,Mihai G. Netea,Mihai G. Netea,Jesper Eugen-Olsen,Miltiades Kyprianou,Periklis Panagopoulos,George N. Dalekos,Evangelos J. Giamarellos-Bourboulis +64 more
TL;DR: The SAVE-MORE trial as discussed by the authors evaluated the efficacy and safety of anakinra, an IL-1α/β inhibitor, in 594 patients with COVID-19 at risk of progressing to respiratory failure.
Journal ArticleDOI
Activate: Randomized Clinical Trial of BCG Vaccination against Infection in the Elderly.
Evangelos J. Giamarellos-Bourboulis,Maria Tsilika,Simone J.C.F.M. Moorlag,Nikolaos Antonakos,Antigone Kotsaki,Jorge Domínguez-Andrés,Evdoxia Kyriazopoulou,Theologia Gkavogianni,Maria-Evangelia Adami,Georgia Damoraki,Panagiotis Koufargyris,Athanassios Karageorgos,Amalia Bolanou,Hans J. P. M. Koenen,Reinout van Crevel,Dionyssia-Irene Droggiti,George Renieris,Antonios Papadopoulos,Mihai G. Netea,Mihai G. Netea +19 more
TL;DR: Data show that BCG vaccination is safe and can protect the elderly against infections, and larger studies are needed to assess protection against respiratory infections, including COVID-19.
Journal ArticleDOI
Serum Hydrogen Sulfide and Outcome Association in Pneumonia by the SARS-CoV-2 Coronavirus.
Georgios Renieris,Konstantina Katrini,Christina Damoulari,Karolina Akinosoglou,Christos Psarrakis,Magdalini Kyriakopoulou,George Dimopoulos,Malvina Lada,Panagiotis Koufargyris,Evangelos J. Giamarellos-Bourboulis +9 more
TL;DR: This research presents a novel probabilistic procedure called “spot-spot analysis” that allows for real-time analysis of the response of the immune system to foreign substance abuse.
Journal ArticleDOI
Author Correction: Early treatment of COVID-19 with anakinra guided by soluble urokinase plasminogen receptor plasma levels: a double-blind, randomized controlled phase 3 trial.
Evdoxia Kyriazopoulou,Garyfallia Poulakou,Haralampos J. Milionis,Simeon Metallidis,Georgios Adamis,Konstantinos Tsiakos,Archontoula Fragkou,Aggeliki Rapti,Christina Damoulari,Massimo Fantoni,Ioannis Kalomenidis,Georgios Chrysos,Andrea Angheben,Ilias Kainis,Zoi Alexiou,Francesco Castelli,Francesco Saverio Serino,Maria Tsilika,Petros Bakakos,Emanuele Nicastri,Vassiliki Tzavara,Evangelos Kostis,Lorenzo Dagna,Panagiotis Koufargyris,Katerina Dimakou,Spyridon Savvanis,Glykeria Tzatzagou,Maria Chini,Giulio Cavalli,Matteo Bassetti,Konstantina Katrini,Vasileios Kotsis,George Tsoukalas,Carlo Selmi,Ioannis Bliziotis,Michael Samarkos,Michael Doumas,Sofia Ktena,Aikaterini Masgala,Ilias Papanikolaou,Maria Kosmidou,Dimitra-Melia Myrodia,Aikaterini Argyraki,Chiara Simona Cardellino,Katerina Koliakou,Eleni-Ioanna Katsigianni,Vassiliki Rapti,Efthymia Giannitsioti,Antonella Cingolani,Styliani Micha,Karolina Akinosoglou,Orestis Liatsis-Douvitsas,Styliani Symbardi,Nikolaos Gatselis,Maria Mouktaroudi,Giuseppe Ippolito,Eleni Florou,Antigone Kotsaki,Mihai G. Netea,Mihai G. Netea,Jesper Eugen-Olsen,Miltiades Kyprianou,Periklis Panagopoulos,George N Dalekos,Evangelos J. Giamarellos-Bourboulis +64 more