G
Gert Storm
Researcher at Utrecht University
Publications - 546
Citations - 36914
Gert Storm is an academic researcher from Utrecht University. The author has contributed to research in topics: Liposome & Drug delivery. The author has an hindex of 96, co-authored 530 publications receiving 32703 citations. Previous affiliations of Gert Storm include National University of Singapore & University of Groningen.
Papers
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Journal Article
Detecting infection and inflammation with technetium-99m-labeled stealth liposomes
Wim J.G. Oyen,O.C. Boerman,Gert Storm,L. van Bloois,E.B. Koenders,Roland A. M. J. Claessens,R.M. Perenboom,Daan J.A. Crommelin,J.W.M. van der Meer,F.H.M. Corstens +9 more
TL;DR: Technetium-99m-Stealth liposomes preferentially accumulated in abscesses, leading to very high target-to-nontarget ratios, which appears to be related to a process based on uptake of long-circulating particles.
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Enhanced localization of liposomes with prolonged blood circulation time in infected lung tissue
TL;DR: In an experimental model of unilateral pneumonia caused by Klebsiella pneumoniae in rats, this article investigated whether intravenous administration of liposomes with prolonged blood circulation time resulted in significant localization of lipo-somes in infected lung tissue.
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Immune cell screening of a nanoparticle library improves atherosclerosis therapy.
Jun Tang,Samantha Baxter,Arjun Menon,Amr Alaarg,Amr Alaarg,Brenda L. Sanchez-Gaytan,Francois Fay,Yiming Zhao,Mireille Ouimet,Mounia S. Braza,Valerie A. Longo,Dalya Abdel-Atti,Raphaël Duivenvoorden,Claudia Calcagno,Gert Storm,Sotirios Tsimikas,Kathryn J. Moore,Filip K. Swirski,Matthias Nahrendorf,Edward A. Fisher,Carlos Pérez-Medina,Zahi A. Fayad,Thomas Reiner,Willem J. M. Mulder +23 more
TL;DR: An in vivo nanoparticle screen approach that involves designing and evaluating a library of nanoparticles with distinct immune cell targeting specificity is presented, which can be used to develop tailored therapies for atherosclerosis and other inflammatory diseases.
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Characterizing EPR-mediated passive drug targeting using contrast-enhanced functional ultrasound imaging
Benjamin Theek,Felix Gremse,Sijumon Kunjachan,Stanley Fokong,Robert Pola,Michal Pechar,Roel Deckers,Gert Storm,Josef Ehling,Fabian Kiessling,Twan Lammers,Twan Lammers,Twan Lammers +12 more
TL;DR: Findings indicate that ceUS can be used to characterize and predict EPR, and potentially also to pre-select patients likely to respond to passively tumor-targeted nanomedicine treatments.
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Complete regression of breast tumour with a single dose of docetaxel-entrapped core-cross-linked polymeric micelles
TL;DR: Preclinical data strongly support clinical translation of this novel nanomedicinal product for the treatment of cancer by covalently conjugating DTX to CCL-PMs via a hydrolysable ester bond.