G
Giacomo Carlo Sturniolo
Researcher at University of Padua
Publications - 212
Citations - 6938
Giacomo Carlo Sturniolo is an academic researcher from University of Padua. The author has contributed to research in topics: Inflammatory bowel disease & Ulcerative colitis. The author has an hindex of 44, co-authored 210 publications receiving 6296 citations. Previous affiliations of Giacomo Carlo Sturniolo include University of Messina.
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Journal ArticleDOI
Mongersen, an Oral SMAD7 Antisense Oligonucleotide, and Crohn’s Disease
Giovanni Monteleone,Markus F. Neurath,Sandro Ardizzone,Antonio Di Sabatino,Massimo Fantini,Fabiana Castiglione,Maria Lia Scribano,Alessandro Armuzzi,Flavio Caprioli,Giacomo Carlo Sturniolo,Francesca Rogai,Maurizio Vecchi,Raja Atreya,Fabrizio Bossa,Sara Onali,Maria Fichera,Gino Roberto Corazza,Livia Biancone,Vincenzo Savarino,Roberta Pica,Ambrogio Orlando,Francesco Pallone +21 more
TL;DR: It was found that study participants with Crohn's disease who received mongersen had significantly higher rates of remission and clinical response than those who received placebo.
Journal ArticleDOI
Toll-Like Receptor 2 Regulates Intestinal Inflammation by Controlling Integrity of the Enteric Nervous System
Paola Brun,Maria Cecilia Giron,Marsela Qesari,Andrea Porzionato,Valentina Caputi,Chiara Zoppellaro,Serena Banzato,Alessia R. Grillo,Lisa Spagnol,Raffaele De Caro,D. Pizzuti,Vito Barbieri,Antonio Rosato,Giacomo Carlo Sturniolo,Diego Martines,Giovanni Zaninotto,Giorgio Palù,Ignazio Castagliuolo +17 more
TL;DR: In mice, TLR2 signaling regulates intestinal inflammation by controlling ENS structure and neurochemical coding, along with intestinal neuromuscular function, and these findings provide information as to how defective TLR 2 signaling in the ENS affects inflammatory bowel disease phenotype in humans.
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Can Calprotectin Predict Relapse Risk in Inflammatory Bowel Disease
Renata D'Incà,Elisabetta Dal Pont,Vincenza Di Leo,L. Benazzato,Matteo Martinato,F. Lamboglia,Lydia Oliva,Giacomo Carlo Sturniolo +7 more
TL;DR: Measuring calprotectin may help to identify UC and colonic CD patients at higher risk of clinical relapse, as well as identifying patients with ulcerative colitis and Crohn's disease in clinical remission with a high likelihood of relapse.
Journal ArticleDOI
Calprotectin and lactoferrin in the assessment of intestinal inflammation and organic disease
Renata D'Incà,Elisabetta Dal Pont,Vincenza Di Leo,Antonio Ferronato,Walter Fries,Maria Grazia Vettorato,Diego Martines,Giacomo Carlo Sturniolo +7 more
TL;DR: Fecal calprotectin and lactoferrin appear to be equally recommendable as inflammatory disease markers in patients with lower gastrointestinal symptoms and both tests are needed to accurately discriminate activity in inflammatory bowel disease patients.
Journal ArticleDOI
HLA-DQA1-HLA-DRB1 variants confer susceptibility to pancreatitis induced by thiopurine immunosuppressants
Graham A. Heap,Michael N. Weedon,Claire Bewshea,Abhey Singh,Mian Chen,Jack B Satchwell,Julian P. Vivian,Kenji So,Patrick Dubois,Jane M. Andrews,Vito Annese,Peter A. Bampton,Martin Barnardo,Sally Bell,Andy Cole,Susan J. Connor,Tom Creed,Fraser Cummings,Mauro D'Amato,Tawfique K. Daneshmend,Richard N. Fedorak,Timothy H. Florin,Daniel R. Gaya,Emma Greig,Jonas Halfvarson,Alisa Hart,Peter M. Irving,Gareth R. Jones,Amir Karban,Ian C. Lawrance,James Lee,Charlie W. Lees,Raffi Lev-Tzion,James O. Lindsay,John C. Mansfield,Joel Mawdsley,Zia Mazhar,Miles Parkes,Kirstie Parnell,Timothy R. Orchard,Graham L. Radford-Smith,Richard K. Russell,David Reffitt,Jack Satsangi,Mark S. Silverberg,Giacomo Carlo Sturniolo,Mark Tremelling,Epameinondas V. Tsianos,David A. van Heel,Alissa Walsh,Gill Watermeyer,Rinse K. Weersma,Sebastian Zeissig,Jamie Rossjohn,Arthur L. Holden,Tariq Ahmad +55 more
TL;DR: Strong evidence of association within the class II HLA region is identified within the HLA-DQA1*02:01–HLA-DRB1*07:01 haplotype, with the most significant association identified at rs2647087, with a 9% risk of developing pancreatitis after administration of a thiopurine.