G
Gilles Dietrich
Researcher at University of Toulouse
Publications - 77
Citations - 3188
Gilles Dietrich is an academic researcher from University of Toulouse. The author has contributed to research in topics: Autoantibody & Antibody. The author has an hindex of 30, co-authored 71 publications receiving 2798 citations. Previous affiliations of Gilles Dietrich include Centre national de la recherche scientifique & Université catholique de Louvain.
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Journal ArticleDOI
Food-Grade Bacteria Expressing Elafin Protect Against Inflammation and Restore Colon Homeostasis
Jean-Paul Motta,Luis G. Bermúdez-Humarán,Céline Deraison,Céline Deraison,Céline Deraison,Laurence Martin,Laurence Martin,Laurence Martin,Corinne Rolland,Corinne Rolland,Corinne Rolland,Perrine Rousset,Perrine Rousset,Perrine Rousset,Jérôme Boué,Jérôme Boué,Jérôme Boué,Gilles Dietrich,Gilles Dietrich,Gilles Dietrich,Kevin Chapman,Pascale Kharrat,Jean-Pierre Vinel,Laurent Alric,Emmanuel Mas,Jean-Michel Sallenave,Jean-Michel Sallenave,Jean-Michel Sallenave,Philippe Langella,Nathalie Vergnolle +29 more
TL;DR: Oral treatment with Elafin-expressing food-grade bacteria protected the gut from inflammatory damage and restored intestinal homeostasis in mouse models of acute and chronic colitis, and suggested that oral delivery of LAB secreting ElafIn may be useful for treating IBD in humans.
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Anti‐idiotypes against Autoantibodies in Normal Immunoglobulins: Evidence for Network Regulation of Human Autoimmune Responses
TL;DR: It is suggested that IVIg may be efficient in selected autoimmune diseases by providing a source of anti-idiotypes with a wide range of specificities brought as interconnected antibody species that may conpensate for altered connectivity of the immune network of patients with autoimmune diseases.
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Natural antibodies to factor VIII (anti-hemophilic factor) in healthy individuals.
TL;DR: It is demonstrated that polyclonal IgG antibodies against procoagulant FVIII are present in healthy individuals as well as natural IgG autoantibodies and/or antibodies directed against epitopes associated with a so far unidentified allotypic polymorphism of the human FV III molecule.
Journal ArticleDOI
V region-mediated selection of autoreactive repertoires by intravenous immunoglobulin (i.v.Ig).
Michel D. Kazatchkine,Gilles Dietrich,Vincent Hurez,Nicoletta Ronda,B. Bellon,F. Rossi,Srinivas V. Kaveri +6 more
TL;DR: In addition to its use as substitute therapy for primary and secondary immunodeficiencies, intravenous immunoglobulin (i.v.Ig) is increasingly being used as an immunomodulating therapy in the treatment of patients with a variety of autoimmune and systemic inflammatory disorders.
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Normal immunoglobulin G (IgG) for therapeutic use (intravenous Ig) contain antiidiotypic specificities against an immunodominant, disease-associated, cross-reactive idiotype of human anti-thyroglobulin autoantibodies.
TL;DR: Results support the concept that IVIg may be beneficial in selected autoimmune diseases by modulating the function of the idiotypic network.