Giuseppe Mancia

TL;DR: A nested case-control study was carried out on a cohort of patients aged 80 years or older (very elderly individuals), who were under treatment with statins between 2008 and 2009, using the database available for all citizenship (about 10 million) of Lombardy (Italy). Cases were the cohort members who experienced death or hospitalization for stroke, myocardial infarction or heart failure from the initial prescription until 2012 as mentioned in this paper.

TL;DR: Findings showed that LA function gradually deteriorated from patients with normotension, across patients with daytime hypertension, to patients with night‐ and day‐nighttime hypertension.

TL;DR: The data show that a sensitive parameter for the development of cognitive impairment is not BP or absolute BP variability but rather its short‐term erratic component, which has been previously shown to be an important prognostic marker for organ damage, cardiovascular, and all‐cause mortality.

TL;DR: Nondipping and reverse dipping BP patterns were related with impaired left atrial phasic function and reverse pattern was the only circadian profile that was independently of other clinical parameters, including night-time BP, associated with decreased reservoir, conduit and contractile function.