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Gudrun M. Jonsdottir

Researcher at deCODE genetics

Publications -  7
Citations -  3899

Gudrun M. Jonsdottir is an academic researcher from deCODE genetics. The author has contributed to research in topics: Population & Recombination. The author has an hindex of 7, co-authored 7 publications receiving 3730 citations.

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A high-resolution recombination map of the human genome

TL;DR: Recombination rates are significantly correlated with both cytogenetic structures and sequence and paternal chromosomes show many differences in locations of recombination maxima, suggesting that there is some underlying component determined by both genetic and environmental factors that affects maternal recombination rates.
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Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.

Daniel F. Gudbjartsson, +77 more
- 01 Mar 2009 - 
TL;DR: A genome-wide association scan for sequence variants affecting eosinophil counts in blood of 9,392 Icelanders found that a nonsynonymous SNP at 12q24, in SH2B3, associated significantly with myocardial infarction in six different populations.
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Sequence variants in the RNF212 gene associate with genome-wide recombination rate.

TL;DR: It is noteworthy that the haplotype formed by two single-nucleotide polymorphisms associated with the highest recombinations in males is associated with a low recombination rate in females, which means that if the frequency of the haplotypes changes, the average recombinations will increase for one sex and decrease for the other, but the sex-averaged recombination rates of the population can stay relatively constant.
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Recombination rate and reproductive success in humans

TL;DR: This work examined genome-wide microsatellite data for 23,066 individuals, providing information on recombination events of 14,140 maternal and paternal meioses each, and found a positive correlation between maternal recombination counts of an offspring and maternal age.