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Nicole M. Warrington
Researcher at University of Queensland
Publications - 119
Citations - 10303
Nicole M. Warrington is an academic researcher from University of Queensland. The author has contributed to research in topics: Genome-wide association study & Offspring. The author has an hindex of 41, co-authored 110 publications receiving 8827 citations. Previous affiliations of Nicole M. Warrington include University of North Carolina at Chapel Hill & Harvard University.
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Journal ArticleDOI
LD Hub: a centralized database and web interface to perform LD score regression that maximizes the potential of summary level GWAS data for SNP heritability and genetic correlation analysis
Jie Zheng,A. Mesut Erzurumluoglu,Benjamin Elsworth,John P. Kemp,Laurence J. Howe,Philip C Haycock,Gibran Hemani,Katherine E. Tansey,Charles Laurin,Early Genetics,Beate St Pourcain,Nicole M. Warrington,Hilary K. Finucane,Hilary K. Finucane,Alkes L. Price,Alkes L. Price,Brendan Bulik-Sullivan,Verneri Anttila,Lavinia Paternoster,Tom R. Gaunt,Tom R. Gaunt,David M. Evans,David M. Evans,Benjamin M. Neale,Benjamin M. Neale +24 more
TL;DR: The proposed LD Hub database and accompanying web interface will ensure maximal uptake of the LD score regression methodology, provide a useful database for the public dissemination of GWAS results, and provide a method for easily screening hundreds of traits for overlapping genetic aetiologies.
Journal ArticleDOI
Sequence variants affecting eosinophil numbers associate with asthma and myocardial infarction.
Daniel F. Gudbjartsson,Unnur S. Bjornsdottir,Unnur S. Bjornsdottir,Eva Halapi,Anna Helgadottir,Patrick Sulem,Gudrun M. Jonsdottir,Gudmar Thorleifsson,Hafdis T. Helgadottir,Valgerdur Steinthorsdottir,Hreinn Stefansson,Carolyn Williams,Jennie Hui,John Beilby,Nicole M. Warrington,Alan L. James,Alan L. James,Lyle J. Palmer,Gerard H. Koppelman,Andrea Heinzmann,Marcus Krueger,H. Marike Boezen,Amanda Wheatley,Janine Altmüller,Hyoung Doo Shin,Soo-Taek Uh,Hyun Sub Cheong,Brynja Jonsdottir,David Gislason,Choon-Sik Park,Linda M. Rasmussen,Celeste Porsbjerg,Jakob Werner Hansen,Vibeke Backer,Thomas Werge,Christer Janson,Ulla-Britt Jönsson,Maggie C.Y. Ng,Juliana C.N. Chan,Wing-Yee So,Ronald C.W. Ma,Svati H. Shah,Christopher B. Granger,Arshed A. Quyyumi,Allan I. Levey,Viola Vaccarino,Muredach P. Reilly,Daniel J. Rader,Michael J.A. Williams,Andre M. van Rij,Gregory T. Jones,Elisabetta Trabetti,Giovanni Malerba,Pier Franco Pignatti,Attilio Boner,Lydia Pescollderungg,Domenico Girelli,Oliviero Olivieri,Nicola Martinelli,Bjorn R. Ludviksson,Dora Ludviksdottir,Gudmundur I. Eyjolfsson,David O. Arnar,Gudmundur Thorgeirsson,Klaus A. Deichmann,Philip J. Thompson,Matthias Wjst,Ian P. Hall,Dirkje S. Postma,Thorarinn Gislason,Jeffrey R. Gulcher,Augustine Kong,Ingileif Jonsdottir,Ingileif Jonsdottir,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Kari Stefansson,Kari Stefansson +77 more
TL;DR: A genome-wide association scan for sequence variants affecting eosinophil counts in blood of 9,392 Icelanders found that a nonsynonymous SNP at 12q24, in SH2B3, associated significantly with myocardial infarction in six different populations.
Journal ArticleDOI
Association between C reactive protein and coronary heart disease: mendelian randomisation analysis based on individual participant data
G. Eiriksdottir,T. B. Harris,L. J. Launer,Vilmundur Gudnason,Aaron R. Folsom,Gavin Andrews,C. M. Ballantyne,Nilesh J. Samani,A. S. Hall,P. S. Braund,A. J. Balmforth,Peter H. Whincup,Richard W Morris,Debbie A Lawlor,Gordon D.O. Lowe,Nicholas J. Timpson,Shah Ebrahim,Yoav Ben-Shlomo,George Davey-Smith,Børge G. Nordestgaard,Anne Tybjærg-Hansen,Jeppe Zacho,Matthew A. Brown,Manjinder S. Sandhu,Sally L. Ricketts,Sofie Ashford,Leslie A. Lange,Alexander P. Reiner,Mary Cushman,Russel Tracy,C. Wu,J. Ge,Y. Zou,A. Sun,Joseph Hung,Brendan McQuillan,Peter L. Thompson,John Beilby,Nicole M. Warrington,Lyle J. Palmer,Christoph Wanner,Christiane Drechsler,Michael Hoffmann,F. G. R. Fowkes,Ioanna Tzoulaki,Meena Kumari,Michelle A. Miller,Michael Marmot,Charlotte Onland-Moret,Y. T. van der Schouw,J.M.A. Boer,Cisca Wijmenga,Kay-Tee Khaw,Ramachandran S. Vasan,Renate B. Schnabel,J. F. Yamamoto,E J Benjamin,Heribert Schunkert,Jeanette Erdmann,Inke R. König,Christian Hengstenberg,Benedetta D. Chiodini,MariaGrazia Franzosi,Silvia Pietri,Francesca Gori,Megan E. Rudock,Yongmei Liu,Kurt Lohman,Steve E. Humphries,Anders Hamsten,Paul Norman,Graeme J. Hankey,Konrad Jamrozik,Eric B. Rimm,J. K. Pai,Bruce M. Psaty,Susan R. Heckbert,J. C. Bis,Salim Yusuf,Sonia S. Anand,Engert Jc,C. Xie,Ryan L. Collins,Robert Clarke,David L.H. Bennett,Jaspal S. Kooner,John C. Chambers,Paul Elliott,W. März,Marcus E. Kleber,Bernhard O. Böhm,Winkelmann Br,Olle Melander,Göran Berglund,Wolfgang Koenig,Barbara Thorand,Jens Baumert,Annette Peters,JoAnn E. Manson,J.A. Cooper,P.J. Talmud,Per Ladenvall,Lovisa Johansson,J. H. Jansson,Göran Hallmans,Muredach P. Reilly,Liming Qu,Man Li,Daniel J. Rader,Hugh Watkins,Jemma C. Hopewell,Danish Saleheen,John Danesh,Philippe M. Frossard,Naveed Sattar,Michele Robertson,J. Shepherd,Ernst J. Schaefer,A. Hofman,J. C. M. Witteman,Isabella Kardys,Abbas Dehghan,U de Faire,Anna M. Bennet,Bruna Gigante,Karin Leander,Bas J M Peters,A.H. Maitland-van der Zee,A.H. De Boer,Olaf H. Klungel,Philip Greenland,J. Dai,Simin Liu,Eric J. Brunner,Mika Kivimäki,Denis St. J. O’Reilly,Ian Ford,Chris J. Packard +137 more
TL;DR: Human genetic data indicate that C reactive protein concentration itself is unlikely to be even a modest causal factor in coronary heart disease.
Journal ArticleDOI
Thirty new loci for age at menarche identified by a meta-analysis of genome-wide association studies
Cathy E. Elks,John R. B. Perry,Patrick Sulem,Daniel I. Chasman,Nora Franceschini,Chunyan He,Kathryn L. Lunetta,Kathryn L. Lunetta,Jenny A. Visser,Enda M. Byrne,Enda M. Byrne,Diana L. Cousminer,Daniel F. Gudbjartsson,Tõnu Esko,Bjarke Feenstra,Jouke-Jan Hottenga,Daniel L. Koller,Zoltán Kutalik,Zoltán Kutalik,Peng Lin,Massimo Mangino,Mara Marongiu,Patrick F. McArdle,Albert V. Smith,Lisette Stolk,Sophie H. Van Wingerden,Jing Hua Zhao,Eva Albrecht,Tanguy Corre,Erik Ingelsson,Caroline Hayward,Patrik K. E. Magnusson,Erin N. Smith,Erin N. Smith,S. Ulivi,Nicole M. Warrington,Lina Zgaga,Helen Alavere,Najaf Amin,Thor Aspelund,Stefania Bandinelli,Inês Barroso,Gerald S. Berenson,Sven Bergmann,Sven Bergmann,Hannah Blackburn,Eric Boerwinkle,Julie E. Buring,Fabio Busonero,Harry Campbell,Stephen J. Chanock,Wei Chen,Marilyn C. Cornelis,David Couper,Andrea D. Coviello,Pio D'Adamo,Ulf de Faire,Eco J. C. de Geus,Panos Deloukas,Angela Döring,George Davey Smith,Douglas F. Easton,Gudny Eiriksdottir,Valur Emilsson,Johan G. Eriksson,Johan G. Eriksson,Luigi Ferrucci,Aaron R. Folsom,Tatiana Foroud,Melissa E. Garcia,Paolo Gasparini,Frank Geller,Christian Gieger,Vilmundur Gudnason,Per Hall,Susan E. Hankinson,Liana Ferreli,Andrew C. Heath,Dena G. Hernandez,Albert Hofman,Frank B. Hu,Thomas Illig,Marjo-Riitta Järvelin,Andrew D. Johnson,David Karasik,Kay-Tee Khaw,Douglas P. Kiel,Tuomas O. Kilpelänen,Ivana Kolcic,Peter Kraft,Lenore J. Launer,Joop S.E. Laven,Shengxu Li,Jianjun Liu,Daniel Levy,Daniel Levy,Nicholas G. Martin,Wendy L. McArdle,Mads Melbye,Vincent Mooser,Jeffrey C. Murray,Sarah S. Murray,Sarah S. Murray,Mike A. Nalls,Pau Navarro,Mari Nelis,Andy R Ness,Kate Northstone,Ben A. Oostra,Munro Peacock,Lyle J. Palmer,Aarno Palotie,Aarno Palotie,Aarno Palotie,Guillaume Paré,Guillaume Paré,Alex Parker,Nancy L. Pedersen,Leena Peltonen,Craig E. Pennell,Paul D.P. Pharoah,Ozren Polasek,Andrew S. Plump,Anneli Pouta,Eleonora Porcu,Thorunn Rafnar,John P. Rice,Susan M. Ring,Fernando Rivadeneira,Igor Rudan,Igor Rudan,Cinzia Sala,Veikko Salomaa,Serena Sanna,David Schlessinger,Nicholas J. Schork,Nicholas J. Schork,Angelo Scuteri,Ayellet V. Segrè,Ayellet V. Segrè,Alan R. Shuldiner,Alan R. Shuldiner,Nicole Soranzo,Nicole Soranzo,Ulla Sovio,Sathanur R. Srinivasan,David P. Strachan,Mar Liis Tammesoo,Emmi Tikkanen,Emmi Tikkanen,Daniela Toniolo,Kim Tsui,Laufey Tryggvadottir,Tyrer Jp,Manuela Uda,Rob M. van Dam,Rob M. van Dam,Joyce B. J. van Meurs,Peter Vollenweider,Gérard Waeber,Nicholas J. Wareham,Dawn M. Waterworth,Michael N. Weedon,H.-Erich Wichmann,Gonneke Willemsen,James F. Wilson,Alan F. Wright,Lauren Young,Guangju Zhai,Wei Vivian Zhuang,Laura J. Bierut,Dorret I. Boomsma,Heather A. Boyd,Laura Crisponi,Ellen W. Demerath,Cornelia M. van Duijn,Michael J. Econs,Tamara B. Harris,David J. Hunter,David J. Hunter,Ruth J. F. Loos,Andres Metspalu,Grant W. Montgomery,Paul M. Ridker,Tim D. Spector,Elizabeth A. Streeten,Kari Stefansson,Kari Stefansson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,André G. Uitterlinden,Elisabeth Widen,Joanne M. Murabito,Joanne M. Murabito,Ken K. Ong,Ken K. Ong,Anna Murray +196 more
TL;DR: A meta-analysis of 32 genome-wide association studies in 87,802 women of European descent found 30 new menarche loci and found suggestive evidence for a further 10 loci, including four previously associated with body mass index and three in or near genes implicated in hormonal regulation.
Journal ArticleDOI
Genome-wide association and large-scale follow up identifies 16 new loci influencing lung function
María Soler Artigas,Daan W. Loth,Louise V. Wain,Sina A. Gharib,Ma'en Obeidat,Wenbo Tang,Guangju Zhai,Guangju Zhai,Jing Hua Zhao,Albert V. Smith,Jennifer E. Huffman,Eva Albrecht,C.M. Jackson,David M. Evans,Gemma Cadby,Gemma Cadby,Myriam Fornage,Ani Manichaikul,Lorna M. Lopez,Toby Johnson,Melinda C. Aldrich,Thor Aspelund,Ins Barroso,Ins Barroso,Harry Campbell,Patricia A. Cassano,David Couper,Gudny Eiriksdottir,Nora Franceschini,Melissa E. Garcia,Christian Gieger,Gauti Kjartan Gislason,Ivica Grković,Christopher J Hammond,Dana B. Hancock,Dana B. Hancock,Tamara B. Harris,Adaikalavan Ramasamy,Adaikalavan Ramasamy,Susan R. Heckbert,Susan R. Heckbert,Markku Heliövaara,Georg Homuth,Pirro G. Hysi,Alan James,Alan James,Stipan Janković,Bonnie R. Joubert,Stefan Karrasch,Norman Klopp,Beate Koch,Stephen B. Kritchevsky,Lenore J. Launer,Yongmei Liu,Laura R. Loehr,Kurt Lohman,Ruth J. F. Loos,Thomas Lumley,Khalid A. Al Balushi,Wei Ang,R. Graham Barr,John Beilby,John D Blakey,Mladen Boban,Vesna Boraska,Jonas Brisman,John Britton,Guy Brusselle,Cyrus Cooper,Ivan Curjuric,Santosh Dahgam,Ian J. Deary,Shah Ebrahim,Mark Eijgelsheim,Clyde Francks,Darya Gaysina,Raquel Granell,Xiangjun Gu,John L. Hankinson,Rebecca Hardy,Sarah E. Harris,John Henderson,Amanda P. Henry,Aroon D. Hingorani,Albert Hofman,Patrick G. Holt,Jennie Hui,Jennie Hui,Michael Hunter,Michael Hunter,Medea Imboden,Karen A. Jameson,Shona M. Kerr,Ivana Kolcic,Florian Kronenberg,Jason Z. Liu,Jonathan Marchini,Tricia M. McKeever,Andrew D. Morris,Anna-Carin Olin,David J. Porteous,Dirkje S. Postma,Stephen S. Rich,Susan M. Ring,Fernando Rivadeneira,Thierry Rochat,Avan Aihie Sayer,Ian Sayers,Peter D. Sly,George Davey Smith,Akshay Sood,John M. Starr,André G. Uitterlinden,Judith M. Vonk,S. Goya Wannamethee,Peter H. Whincup,Cisca Wijmenga,O. Dale Williams,Andrew Wong,Massimo Mangino,Kristin D. Marciante,Wendy L. McArdle,Bernd Meibohm,Alanna C. Morrison,Kari E. North,Ernst Omenaas,Lyle J. Palmer,Lyle J. Palmer,Kirsi H. Pietiläinen,Isabelle Pin,Ozren Polasek,Anneli Pouta,Bruce M. Psaty,Bruce M. Psaty,Anna-Liisa Hartikainen,Taina Rantanen,Samuli Ripatti,Samuli Ripatti,Jerome I. Rotter,Igor Rudan,Igor Rudan,Alicja R. Rudnicka,Holger Schulz,So-Youn Shin,Tim D. Spector,Ida Surakka,Ida Surakka,Veronique Vitart,Henry Völzke,Nicholas J. Wareham,Nicole M. Warrington,Nicole M. Warrington,H.-Erich Wichmann,Sarah H. Wild,Jemma B. Wilk,Matthias Wjst,Alan F. Wright,Lina Zgaga,Lina Zgaga,Tatijana Zemunik,Craig E. Pennell,Fredrik Nyberg,Fredrik Nyberg,Diana Kuh,John W. Holloway,H. Marike Boezen,Debbie A Lawlor,Richard W Morris,Nicole Probst-Hensch,Jaakko Kaprio,Jaakko Kaprio,James F. Wilson,Caroline Hayward,Mika Kähönen,Joachim Heinrich,Arthur W. Musk,Arthur W. Musk,Deborah Jarvis,Deborah Jarvis,Sven Gläser,Sven Gläser,Marjo-Riitta Järvelin,Bruno H. Ch. Stricker,Bruno H. Ch. Stricker,Paul Elliott,Paul Elliott,George T. O'Connor,George T. O'Connor,David P. Strachan,Stephanie J. London,Ian P. Hall,Vilmundur Gudnason,Martin D. Tobin +192 more
TL;DR: This article identified new regions showing association with pulmonary function in or near MFAP2, TGFB2, HDAC4, RARB, MECOM (also known as EVI1), SPATA9, ARMC2, NCR3, ZKSCAN3, CDC123, C10orf11, LRP1, CCDC38, MMP15, CFDP1 and KCNE2.