W
Wouter J. Peyrot
Researcher at VU University Amsterdam
Publications - 63
Citations - 8086
Wouter J. Peyrot is an academic researcher from VU University Amsterdam. The author has contributed to research in topics: Genome-wide association study & Major depressive disorder. The author has an hindex of 28, co-authored 50 publications receiving 6249 citations. Previous affiliations of Wouter J. Peyrot include Broad Institute & Harvard University.
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Journal ArticleDOI
Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
Naomi R. Wray,Stephan Ripke,Stephan Ripke,Stephan Ripke,Manuel Mattheisen,Maciej Trzaskowski,Enda M. Byrne,Abdel Abdellaoui,Mark Adams,Esben Agerbo,Esben Agerbo,Tracy Air,Till M.F. Andlauer,Silviu Alin Bacanu,Marie Bækvad-Hansen,Marie Bækvad-Hansen,Aartjan F.T. Beekman,Tim B. Bigdeli,Elisabeth B. Binder,Elisabeth B. Binder,Douglas Blackwood,Julien Bryois,Henriette N. Buttenschøn,Henriette N. Buttenschøn,Jonas Bybjerg-Grauholm,Jonas Bybjerg-Grauholm,Na Cai,Na Cai,Enrique Castelao,Jane H. Christensen,Jane H. Christensen,Toni-Kim Clarke,Jonathan I.R. Coleman,Lucía Colodro-Conde,Baptiste Couvy-Duchesne,Nicholas John Craddock,Gregory E. Crawford,Cheynna A. Crowley,Hassan S. Dashti,Hassan S. Dashti,Gail Davies,Ian J. Deary,Franziska Degenhardt,Eske M. Derks,Nese Direk,Nese Direk,Conor V. Dolan,Erin C. Dunn,Erin C. Dunn,Thalia C. Eley,Nicholas Eriksson,Valentina Escott-Price,Farnush Hassan Farhadi Kiadeh,Hilary K. Finucane,Hilary K. Finucane,Andreas J. Forstner,Josef Frank,Helena Gaspar,Michael Gill,Paola Giusti-Rodríguez,Fernando S. Goes,Scott D. Gordon,Jakob Grove,Lynsey S. Hall,Lynsey S. Hall,Eilis Hannon,Christine Søholm Hansen,Christine Søholm Hansen,Thomas Hansen,Thomas Hansen,Stefan Herms,Stefan Herms,Ian B. Hickie,Per Hoffmann,Per Hoffmann,Georg Homuth,Carsten Horn,Jouke-Jan Hottenga,David M. Hougaard,David M. Hougaard,Ming Hu,Craig L. Hyde,Marcus Ising,Rick Jansen,Fulai Jin,Eric Jorgenson,James A. Knowles,Isaac S. Kohane,Isaac S. Kohane,Isaac S. Kohane,Julia Kraft,Warren W. Kretzschmar,Jesper Krogh,Zoltán Kutalik,Zoltán Kutalik,Jacqueline M. Lane,Jacqueline M. Lane,Yihan Li,Yun Li,Penelope A. Lind,Xiaoxiao Liu,Leina Lu,Donald J. MacIntyre,Dean F. MacKinnon,Robert Maier,Wolfgang Maier,Jonathan Marchini,Hamdi Mbarek,Patrick J. McGrath,Peter McGuffin,Sarah E. Medland,Divya Mehta,Divya Mehta,Christel M. Middeldorp,Christel M. Middeldorp,Evelin Mihailov,Yuri Milaneschi,Lili Milani,Jonathan Mill,Francis M. Mondimore,Grant W. Montgomery,Sara Mostafavi,Niamh Mullins,Matthias Nauck,Bernard Ng,Michel G. Nivard,Dale R. Nyholt,Paul F. O'Reilly,Hogni Oskarsson,Michael John Owen,Jodie N. Painter,Carsten Bøcker Pedersen,Carsten Bøcker Pedersen,Marianne Giørtz Pedersen,Marianne Giørtz Pedersen,Roseann E. Peterson,Erik Pettersson,Wouter J. Peyrot,Giorgio Pistis,Danielle Posthuma,Shaun Purcell,Jorge A. Quiroz,Per Qvist,Per Qvist,John P. Rice,Brien P. Riley,Margarita Rivera,Margarita Rivera,Saira Saeed Mirza,Richa Saxena,Richa Saxena,Robert A. Schoevers,Eva C. Schulte,Ling Shen,Jianxin Shi,Stanley I. Shyn,Engilbert Sigurdsson,Grant Sinnamon,Johannes H. Smit,Daniel J. Smith,Hreinn Stefansson,Stacy Steinberg,Craig A. Stockmeier,Fabian Streit,Jana Strohmaier,Katherine E. Tansey,Henning Teismann,Alexander Teumer,Wesley K. Thompson,Pippa A. Thomson,Thorgeir E. Thorgeirsson,Chao Tian,Matthew Traylor,Jens Treutlein,Vassily Trubetskoy,André G. Uitterlinden,Daniel Umbricht,Sandra Van der Auwera,Albert M. van Hemert,Alexander Viktorin,Peter M. Visscher,Yunpeng Wang,Yunpeng Wang,Yunpeng Wang,Bradley T. Webb,Shantel Weinsheimer,Shantel Weinsheimer,Jürgen Wellmann,Gonneke Willemsen,Stephanie H. Witt,Yang Wu,Hualin S. Xi,Jian Yang,Futao Zhang,Volker Arolt,Bernhard T. Baune,Klaus Berger,Dorret I. Boomsma,Sven Cichon,Udo Dannlowski,E. C.J. De Geus,J. Raymond DePaulo,Enrico Domenici,Katharina Domschke,Tõnu Esko,Tõnu Esko,Hans J. Grabe,Steven P. Hamilton,Caroline Hayward,Andrew C. Heath,David A. Hinds,Kenneth S. Kendler,Stefan Kloiber,Stefan Kloiber,Stefan Kloiber,Glyn Lewis,Qingqin S. Li,Susanne Lucae,Pamela F.A. Madden,Patrik K. E. Magnusson,Nicholas G. Martin,Andrew M. McIntosh,Andres Metspalu,Ole Mors,Ole Mors,Preben Bo Mortensen,Bertram Müller-Myhsok,Bertram Müller-Myhsok,Merete Nordentoft,Merete Nordentoft,Markus M. Nöthen,Michael Conlon O'Donovan,Sara A. Paciga,Nancy L. Pedersen,Brenda W.J.H. Penninx,Roy H. Perlis,David J. Porteous,James B. Potash,Martin Preisig,Marcella Rietschel,Catherine Schaefer,Thomas G. Schulze,Jordan W. Smoller,Jordan W. Smoller,Kari Stefansson,Kari Stefansson,Henning Tiemeier,Rudolf Uher,Henry Völzke,Myrna M. Weissman,Myrna M. Weissman,Thomas Werge,Thomas Werge,Thomas Werge,Ashley R. Winslow,Ashley R. Winslow,Cathryn M. Lewis,Douglas F. Levinson,Gerome Breen,Anders D. Børglum,Anders D. Børglum,Patrick F. Sullivan,Patrick F. Sullivan +262 more
TL;DR: A genome-wide association meta-analysis of individuals with clinically assessed or self-reported depression identifies 44 independent and significant loci and finds important relationships of genetic risk for major depression with educational attainment, body mass, and schizophrenia.
Journal ArticleDOI
Genome-wide association study identifies 74 loci associated with educational attainment
Aysu Okbay,Jonathan P. Beauchamp,Mark Alan Fontana,James J. Lee,Tune H. Pers,Cornelius A. Rietveld,Patrick Turley,Guo-Bo Chen,Valur Emilsson,S. Fleur W. Meddens,S. Fleur W. Meddens,S. Fleur W. Meddens,Sven Oskarsson,Joseph K. Pickrell,Kevin Thom,Pascal Timshel,Pascal Timshel,Ronald de Vlaming,Abdel Abdellaoui,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Jonas Bacelis,Clemens Baumbach,Gyda Bjornsdottir,Johannes H. Brandsma,Maria Pina Concas,Jaime Derringer,Nicholas A. Furlotte,Tessel E. Galesloot,Giorgia Girotto,Richa Gupta,Leanne M. Hall,Leanne M. Hall,Sarah E. Harris,Edith Hofer,Momoko Horikoshi,Momoko Horikoshi,Jennifer E. Huffman,Kadri Kaasik,Ioanna P. Kalafati,Robert Karlsson,Augustine Kong,Jari Lahti,Sven J. van der Lee,C. deLeeuw,C. deLeeuw,Penelope A. Lind,Karl-Oskar Lindgren,Tian Liu,Massimo Mangino,Massimo Mangino,Jonathan Marten,Evelin Mihailov,Michael B. Miller,Peter J. van der Most,Christopher Oldmeadow,Antony Payton,Natalia Pervjakova,Natalia Pervjakova,Wouter J. Peyrot,Yong Qian,Olli T. Raitakari,Rico Rueedi,Rico Rueedi,Erika Salvi,Börge Schmidt,Katharina E. Schraut,Jianxin Shi,Albert V. Smith,Raymond A. Poot,Beate St Pourcain,Alexander Teumer,Gudmar Thorleifsson,Niek Verweij,Dragana Vuckovic,Juergen Wellmann,Harm-Jan Westra,Harm-Jan Westra,Jingyun Yang,Wei Zhao,Zhihong Zhu,Behrooz Z. Alizadeh,Najaf Amin,Andrew Bakshi,Sebastian E. Baumeister,Sebastian E. Baumeister,Ginevra Biino,Klaus Bønnelykke,Patricia A. Boyle,Harry Campbell,Francesco P. Cappuccio,Gail Davies,Jan-Emmanuel De Neve,Panos Deloukas,Panos Deloukas,Ilja Demuth,Jun Ding,Peter Eibich,Peter Eibich,Lewin Eisele,Niina Eklund,David M. Evans,David M. Evans,Jessica D. Faul,Mary F. Feitosa,Andreas J. Forstner,Ilaria Gandin,Bjarni Gunnarsson,Bjarni V. Halldorsson,Bjarni V. Halldorsson,Tamara B. Harris,Andrew C. Heath,Lynne J. Hocking,Elizabeth G. Holliday,Georg Homuth,Michael A. Horan,Jouke-Jan Hottenga,Philip L. De Jager,Philip L. De Jager,Philip L. De Jager,Peter K. Joshi,Astanand Jugessur,Marika Kaakinen,Mika Kähönen,Stavroula Kanoni,Liisa Keltigangas-Jarvinen,Lambertus A. Kiemeney,Ivana Kolcic,Seppo Koskinen,Aldi T. Kraja,Martin Kroh,Zoltán Kutalik,Zoltán Kutalik,Antti Latvala,Lenore J. Launer,Maël Lebreton,Douglas F. Levinson,Paul Lichtenstein,Peter Lichtner,David C. Liewald,Anu Loukola,Pamela A. F. Madden,Reedik Mägi,Tomi Mäki-Opas,Riccardo E. Marioni,Riccardo E. Marioni,Pedro Marques-Vidal,Gerardus A. Meddens,George McMahon,Christa Meisinger,Thomas Meitinger,Y. Milaneschi,Lili Milani,Grant W. Montgomery,Ronny Myhre,Christopher P. Nelson,Christopher P. Nelson,Dale R. Nyholt,William E R Ollier,Aarno Palotie,Lavinia Paternoster,Nancy L. Pedersen,K. Petrovic,David J. Porteous,Katri Räikkönen,Susan M. Ring,Antonietta Robino,Olga Rostapshova,Igor Rudan,Aldo Rustichini,Veikko Salomaa,Alan R. Sanders,Alan R. Sanders,Antti-Pekka Sarin,Antti-Pekka Sarin,Helena Schmidt,Rodney J. Scott,Blair H. Smith,Jennifer A. Smith,Jan A. Staessen,Jan A. Staessen,Elisabeth Steinhagen-Thiessen,Konstantin Strauch,Antonio Terracciano,Martin D. Tobin,Sheila Ulivi,Simona Vaccargiu,Lydia Quaye,Frank J. A. van Rooij,Cristina Venturini,Cristina Venturini,Anna A. E. Vinkhuyzen,Uwe Völker,Henry Völzke,Judith M. Vonk,Diego Vozzi,Johannes Waage,Johannes Waage,Erin B. Ware,Gonneke Willemsen,John Attia,David A. Bennett,Klaus Berger,Lars Bertram,Lars Bertram,Hans Bisgaard,Dorret I. Boomsma,Ingrid B. Borecki,Ute Bültmann,Christopher F. Chabris,Francesco Cucca,Daniele Cusi,Daniele Cusi,Ian J. Deary,George Dedoussis,Cornelia M. van Duijn,Johan G. Eriksson,Barbara Franke,Lude Franke,Paolo Gasparini,Paolo Gasparini,Pablo V. Gejman,Pablo V. Gejman,Christian Gieger,Hans-Jörgen Grabe,Jacob Gratten,Patrick J. F. Groenen,Vilmundur Gudnason,Pim van der Harst,Caroline Hayward,David A. Hinds,Wolfgang Hoffmann,Elina Hyppönen,Elina Hyppönen,William G. Iacono,Bo Jacobsson,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Jaakko Kaprio,Jaakko Kaprio,Sharon L.R. Kardia,Terho Lehtimäki,Steven F. Lehrer,Steven F. Lehrer,Patrik K. E. Magnusson,Nicholas G. Martin,Matt McGue,Andres Metspalu,Neil Pendleton,Neil Pendleton,Brenda W.J.H. Penninx,Markus Perola,Markus Perola,Nicola Pirastu,Mario Pirastu,Ozren Polasek,Ozren Polasek,Danielle Posthuma,Christine Power,Michael A. Province,Nilesh J. Samani,Nilesh J. Samani,David Schlessinger,Reinhold Schmidt,Thorkild I. A. Sørensen,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Kari Stefansson,Unnur Thorsteinsdottir,Unnur Thorsteinsdottir,Roy Thurik,Nicholas J. Timpson,Henning Tiemeier,Joyce Y. Tung,André G. Uitterlinden,Veronique Vitart,Peter Vollenweider,David R. Weir,James F. Wilson,Alan F. Wright,Dalton Conley,Robert F. Krueger,George Davey Smith,Albert Hofman,David Laibson,Sarah E. Medland,Michelle N. Meyer,Jian Yang,Magnus Johannesson,Peter M. Visscher,Tõnu Esko,Philipp Koellinger,Philipp Koellinger,Philipp Koellinger,David Cesarini,Daniel J. Benjamin +296 more
TL;DR: In this article, the results of a genome-wide association study (GWAS) for educational attainment were reported, showing that single-nucleotide polymorphisms associated with educational attainment disproportionately occur in genomic regions regulating gene expression in the fetal brain.
Genome-wide association study identifies 74 loci associated with educational attainment
Aysu Okbay,Jonathan P. Beauchamp,Mark Alan Fontana,James J. Lee,Tune H. Pers,Cornelius A. Rietveld,Patrick Turley,Guo-Bo Chen,Valur Emilsson,S. Fleur W. Meddens,Sven Oskarsson,Joseph K. Pickrell,Kevin Thom,Pascal Timshel,Ronald de Vlaming,Abdel Abdellaoui,Tarunveer S. Ahluwalia,Jonas Bacelis,Clemens Baumbach,Gyda Bjornsdottir,Johannes H. Brandsma,Maria Pina Concas,Jaime Derringer,Nicholas A. Furlotte,Tessel E. Galesloot,Giorgia Girotto,Richa Gupta,Leanne M. Hall,Sarah E. Harris,Edith Hofer,Momoko Horikoshi,Jennifer E. Huffman,Kadri Kaasik,Ioanna P. Kalafati,Robert Karlsson,Augustine Kong,Jari Lahti,Sven J. van der Lee,Christiaan de Leeuw,Penelope A. Lind,Karl-Oskar Lindgren,Tian Liu,Massimo Mangino,Jonathan Marten,Evelin Mihailov,Michael B. Miller,Peter J. van der Most,Christopher Oldmeadow,Antony Payton,Natalia Pervjakova,Wouter J. Peyrot,Yong Qian,Olli T. Raitakari,Rico Rueedi,Erika Salvi,Brge Schmidt,Katharina E. Schraut,Jianxin Shi,Albert V. Smith,Raymond A. Poot,Beate St Pourcain,Alexander Teumer,Gudmar Thorleifsson,Niek Verweij,Dragana Vuckovic,Juergen Wellmann,Harm-Jan Westra,Jingyun Yang,Wei Zhao,Zhihong Zhu,Behrooz Z. Alizadeh,Najaf Amin,Andrew Bakshi,Sebastian E. Baumeister,Ginevra Biino,Klaus Bønnelykke,Patricia A. Boyle,Harry Campbell,Francesco P. Cappuccio,Gail Davies,Jan-Emmanuel De Neve,Panos Deloukas,Ilja Demuth,Jun Ding,Peter Eibich,Lewin Eisele,Niina Eklund,David M. Evans,Jessica D. Faul,Mary F. Feitosa,Andreas J. Forstner,Ilaria Gandin,Bjarni Gunnarsson,Bjarni V. Halldorsson,Tamara B. Harris,Andrew C. Heath,Lynne J. Hocking,Elizabeth G. Holliday,Georg Homuth,Michael A. Horan,Jouke-Jan Hottenga,Philip L. De Jager,Peter K. Joshi,Astanand Jugessur,Marika Kaakinen,Mika Kähönen,Stavroula Kanoni,Liisa Keltigangas-Jarvinen,Lambertus A. Kiemeney,Ivana Kolcic,Seppo Koskinen,Aldi T. Kraja,Martin Kroh,Zoltán Kutalik,Antti Latvala,Lenore J. Launer,Maël Lebreton,Douglas F. Levinson,Paul Lichtenstein,Peter Lichtner,David C. Liewald,Anu Loukola,Pamela A. F. Madden,Reedik Mägi,Tomi Mäki-Opas,Riccardo E. Marioni,Pedro Marques-Vidal,Gerardus A. Meddens,George McMahon,Christa Meisinger,Thomas Meitinger,Y. Milaneschi,Lili Milani,Grant W. Montgomery,Ronny Myhre,Christopher P. Nelson,Dale R. Nyholt,William E R Ollier,Aarno Palotie,Lavinia Paternoster,Nancy L. Pedersen,K. Petrovic,David J. Porteous,Katri Räikkönen,Susan M. Ring,Antonietta Robino,Olga Rostapshova,Igor Rudan,Aldo Rustichini,Veikko Salomaa,Alan R. Sanders,Antti-Pekka Sarin,Helena Schmidt,Rodney J. Scott,Blair H. Smith,Jennifer A. Smith,Jan A. Staessen,Elisabeth Steinhagen-Thiessen,Konstantin Strauch,Antonio Terracciano,Martin D. Tobin,Sheila Ulivi,Simona Vaccargiu,Lydia Quaye,Frank J. A. van Rooij,Cristina Venturini,Anna A. E. Vinkhuyzen,Uwe Völker,Henry Völzke,Judith M. Vonk,Diego Vozzi,Johannes Waage,Erin B. Ware,Gonneke Willemsen,John Attia,David A. Bennett,Klaus Berger,Lars Bertram,Hans Bisgaard,Dorret I. Boomsma,Ingrid B. Borecki,Ute Bültmann,Christopher F. Chabris,Francesco Cucca,Daniele Cusi,Ian J. Deary,George Dedoussis,Cornelia M. van Duijn,Johan G. Eriksson,Barbara Franke,Lude Franke,Paolo Gasparini,Pablo V. Gejman,Christian Gieger,Hans-Jörgen Grabe,Jacob Gratten,Patrick J. F. Groenen,Vilmundur Gudnason,Pim van der Harst,Caroline Hayward,David A. Hinds,Wolfgang Hoffmann,Elina Hyppnen,William G. Iacono,Bo Jacobsson,Marjo-Riitta Järvelin,Karl-Heinz Jöckel,Jaakko Kaprio,Sharon L.R. Kardia,Terho Lehtimäki,Steven F. Lehrer,Patrik K. E. Magnusson,Nicholas G. Martin,Matt McGue,Andres Metspalu,Neil Pendleton,Brenda W.J.H. Penninx,Markus Perola,Nicola Pirastu,Mario Pirastu,Ozren Polasek,Danielle Posthuma,Christine Power,Michael A. Province,Nilesh J. Samani,David Schlessinger,Reinhold Schmidt,Thorkild I. A. Sørensen,Tim D. Spector,Kari Stefansson,Unnur Thorsteinsdottir,Roy Thurik,Nicholas J. Timpson,Henning Tiemeier,Joyce Y. Tung,André G. Uitterlinden,Veronique Vitart,Peter Vollenweider,David R. Weir,James F. Wilson,Alan F. Wright,Dalton Conley,Robert F. Krueger,George Davey Smith,Albert Hofman,David Laibson,Sarah E. Medland,Michelle N. Meyer,Jian Yang,Magnus Johannesson,Peter M. Visscher,Tõnu Esko,Philipp Koellinger,David Cesarini,Daniel J. Benjamin +254 more
Journal ArticleDOI
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
Cornelius A. Rietveld,Sarah E. Medland,Jaime Derringer,Jian Yang,Tõnu Esko,Nicolas W. Martin,Nicolas W. Martin,Harm-Jan Westra,Konstantin Shakhbazov,Abdel Abdellaoui,Arpana Agrawal,Eva Albrecht,Behrooz Z. Alizadeh,Najaf Amin,John Barnard,Sebastian E. Baumeister,Kelly S. Benke,Lawrence F. Bielak,Jeffrey A. Boatman,Patricia A. Boyle,Gail Davies,Christiaan de Leeuw,Niina Eklund,Niina Eklund,Daniel S. Evans,Rudolf Ferhmann,Krista Fischer,Christian Gieger,Håkon K. Gjessing,Sara Hägg,Sara Hägg,Jennifer R. Harris,Caroline Hayward,Christina Holzapfel,Carla A. Ibrahim-Verbaas,Erik Ingelsson,Erik Ingelsson,Bo Jacobsson,Bo Jacobsson,Peter K. Joshi,Astanand Jugessur,Marika Kaakinen,Stavroula Kanoni,Juha Karjalainen,Ivana Kolcic,Kati Kristiansson,Kati Kristiansson,Zoltán Kutalik,Zoltán Kutalik,Jari Lahti,Sang Hong Lee,Peng Lin,Penelope A. Lind,Yongmei Liu,Kurt Lohman,Marisa Loitfelder,George McMahon,Pedro Marques Vidal,Osorio Meirelles,Lili Milani,Ronny Myhre,Marja-Liisa Nuotio,Marja-Liisa Nuotio,Christopher Oldmeadow,Katja Petrovic,Wouter J. Peyrot,Ozren Polasek,Lydia Quaye,Eva Reinmaa,John P. Rice,Thais S. Rizzi,Helena Schmidt,Reinhold Schmidt,Albert V. Smith,Jennifer A. Smith,Toshiko Tanaka,Antonio Terracciano,Antonio Terracciano,Matthijs J. H. M. van der Loos,Veronique Vitart,Henry Völzke,Jürgen Wellmann,Lei Yu,Wei Zhao,Jüri Allik,John Attia,Stefania Bandinelli,François Bastardot,Jonathan P. Beauchamp,David A. Bennett,Klaus Berger,Laura J. Bierut,Dorret I. Boomsma,Ute Bültmann,Harry Campbell,Christopher F. Chabris,Lynn Cherkas,Mina K. Chung,Francesco Cucca,Francesco Cucca,Mariza de Andrade,Philip L. De Jager,Jan-Emmanuel De Neve,Jan-Emmanuel De Neve,Ian J. Deary,George Dedoussis,Panos Deloukas,Maria Dimitriou,Guoný Eiríksdóttir,Martin F. Elderson,Johan G. Eriksson,David M. Evans,Jessica D. Faul,Luigi Ferrucci,Melissa E. Garcia,Henrik Grönberg,Vilmundur Guonason,Per Hall,Juliette Harris,Tamara B. Harris,Nicholas D. Hastie,Andrew C. Heath,Dena G. Hernandez,Wolfgang Hoffmann,Adriaan Hofman,Rolf Holle,Elizabeth G. Holliday,Jouke-Jan Hottenga,William G. Iacono,Thomas Illig,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Marjo-Riitta Järvelin,Mika Kähönen,Jaakko Kaprio,Jaakko Kaprio,Robert M. Kirkpatrick,Matthew Kowgier,Antti Latvala,Antti Latvala,Lenore J. Launer,Debbie A Lawlor,Terho Lehtimäki,Jingmei Li,Paul Lichtenstein,Peter Lichtner,David C. Liewald,Pamela A. F. Madden,Patrik K. E. Magnusson,Tomi E. Mäkinen,Marco Masala,Matt McGue,Andres Metspalu,Andreas Mielck,Michael B. Miller,Grant W. Montgomery,Sutapa Mukherjee,Sutapa Mukherjee,Dale R. Nyholt,Ben A. Oostra,Lyle J. Palmer,Aarno Palotie,Aarno Palotie,Brenda W.J.H. Penninx,Markus Perola,Markus Perola,Markus Perola,Patricia A. Peyser,Martin Preisig,Katri Räikkönen,Olli T. Raitakari,Anu Realo,Susan M. Ring,Samuli Ripatti,Samuli Ripatti,Samuli Ripatti,Fernando Rivadeneira,Igor Rudan,Aldo Rustichini,Veikko Salomaa,Antti-Pekka Sarin,David Schlessinger,Rodney J. Scott,Harold Snieder,Beate St Pourcain,John M. Starr,Jae Hoon Sul,Ida Surakka,Ida Surakka,Rauli Svento,Alexander Teumer,Henning Tiemeier,Frank J. A. van Rooij,David R. Van Wagoner,Erkki Vartiainen,Jorma Viikari,Peter Vollenweider,Judith M. Vonk,Gérard Waeber,David R. Weir,H.-Erich Wichmann,Elisabeth Widen,Gonneke Willemsen,James F. Wilson,Alan F. Wright,Dalton Conley,George Davey-Smith,Lude Franke,Patrick J. F. Groenen,Albert Hofman,Magnus Johannesson,Sharon L.R. Kardia,Robert F. Krueger,David Laibson,Nicholas G. Martin,Michelle N. Meyer,Michelle N. Meyer,Danielle Posthuma,Danielle Posthuma,Roy Thurik,Nicholas J. Timpson,André G. Uitterlinden,Cornelia M. van Duijn,Cornelia M. van Duijn,Peter M. Visscher,Peter M. Visscher,Daniel J. Benjamin,David Cesarini,David Cesarini,David Cesarini,Philipp Koellinger +230 more
TL;DR: In this article, a genome-wide association study of educational attainment was conducted in a discovery sample of 101,069 individuals and a replication sample of 25,490 individuals, and three independent SNPs are genome wide significant (rs9320913, rs11584700, rs4851266).
Journal ArticleDOI
Genome-wide physical activity interactions in adiposity. A meta-analysis of 200,452 adults
Mariaelisa Graff,Robert A. Scott,Anne E. Justice,Kristin L. Young,Mary F. Feitosa,Llilda Barata,Thomas W. Winkler,Audrey Y. Chu,Audrey Y. Chu,Anubha Mahajan,David Hadley,Luting Xue,Luting Xue,Tsegaselassie Workalemahu,Nancy L. Heard-Costa,Nancy L. Heard-Costa,Marcel den Hoed,Marcel den Hoed,Tarunveer S. Ahluwalia,Tarunveer S. Ahluwalia,Qibin Qi,Julius S. Ngwa,Frida Renström,Frida Renström,Lydia Quaye,John D. Eicher,James E. Hayes,James E. Hayes,Marilyn C. Cornelis,Marilyn C. Cornelis,Marilyn C. Cornelis,Zoltán Kutalik,Zoltán Kutalik,Elise Lim,Jian'an Luan,Jennifer E. Huffman,Jennifer E. Huffman,Weihua Zhang,Weihua Zhang,Wei Zhao,Paula J. Griffin,Toomas Haller,Shafqat Ahmad,Pedro Marques-Vidal,Stephanie A. Bien,Loic Yengo,Alexander Teumer,Albert V. Smith,Meena Kumari,Marie Neergaard Harder,Johanne Marie Justesen,Marcus E. Kleber,Marcus E. Kleber,Mette Hollensted,Kurt Lohman,Natalia V. Rivera,John Whitfield,Jing Hua Zhao,Heather M. Stringham,Leo-Pekka Lyytikäinen,Charlotte Huppertz,Charlotte Huppertz,Gonneke Willemsen,Gonneke Willemsen,Wouter J. Peyrot,Ying Wu,Kati Kristiansson,Kati Kristiansson,Ayse Demirkan,Ayse Demirkan,Myriam Fornage,Maija Hassinen,Lawrence F. Bielak,Gemma Cadby,Toshiko Tanaka,Reedik Mägi,Peter J. van der Most,Anne U. Jackson,Jennifer L. Bragg-Gresham,Veronique Vitart,Jonathan Marten,Pau Navarro,Claire Bellis,Claire Bellis,Dorota Pasko,Åsa Johansson,Soren Snitker,Yu-Ching Cheng,Joel Eriksson,Unhee Lim,Mette Aadahl,Mette Aadahl,Linda S. Adair,Najaf Amin,Beverley Balkau,Juha Auvinen,Juha Auvinen,John Beilby,John Beilby,Richard N. Bergman,Sven Bergmann,Sven Bergmann,Alain G. Bertoni,John Blangero,Amélie Bonnefond,Lori L. Bonnycastle,Judith B. Borja,Soren Brage,Fabio Busonero,Steve Buyske,Harry Campbell,Peter S. Chines,Francis S. Collins,Tanguy Corre,Tanguy Corre,George Davey Smith,Graciela E. Delgado,Nicole Dueker,Marcus Dörr,Tapani Ebeling,Tapani Ebeling,Gudny Eiriksdottir,Tõnu Esko,Jessica D. Faul,Mao Fu,Kristine Færch,Christian Gieger,Sven Gläser,Jian Gong,Penny Gordon-Larsen,Harald Grallert,Tanja B. Grammer,Niels Grarup,Gerard van Grootheest,Kennet Harald,Nicholas D. Hastie,Aki S. Havulinna,Dena G. Hernandez,Lucia A. Hindorff,Lynne J. Hocking,Lynne J. Hocking,Oddgeir L. Holmens,Christina Holzapfel,Jouke-Jan Hottenga,Jie Huang,Tao Huang,Jennie Hui,Jennie Hui,Cornelia Huth,Nina Hutri-Kähönen,Alan James,Alan James,John-Olov Jansson,Min A. Jhun,Markus Juonala,Markus Juonala,Leena Kinnunen,Heikki A. Koistinen,Heikki A. Koistinen,Heikki A. Koistinen,Ivana Kolcic,Pirjo Komulainen,Johanna Kuusisto,Kirsti Kvaløy,Mika Kähönen,Timo A. Lakka,Lenore J. Launer,Benjamin Lehne,Cecilia M. Lindgren,Cecilia M. Lindgren,Cecilia M. Lindgren,Mattias Lorentzon,Mattias Lorentzon,Robert Luben,Michel Marre,Yuri Milaneschi,Keri L. Monda,Keri L. Monda,Grant W. Montgomery,Marleen H.M. de Moor,Marleen H.M. de Moor,Antonella Mulas,Martina Müller-Nurasyid,Arthur W. Musk,Arthur W. Musk,Reija Männikkö,Satu Männistö,Narisu Narisu,Matthias Nauck,Jennifer A. Nettleton,Ilja M. Nolte,Albertine J. Oldehinkel,Matthias Olden,Ken K. Ong,Sandosh Padmanabhan,Sandosh Padmanabhan,Lavinia Paternoster,Jeremiah Perez,Markus Perola,Markus Perola,Markus Perola,Annette Peters,Ulrike Peters,Patricia A. Peyser,Inga Prokopenko,Hannu Puolijoki,Olli T. Raitakari,Olli T. Raitakari,Tuomo Rankinen,Laura J. Rasmussen-Torvik,Rajesh Rawal,Paul M. Ridker,Paul M. Ridker,Lynda M. Rose,Igor Rudan,Cinzia Sarti,Mark A. Sarzynski,Kai Savonen,William R. Scott,Serena Sanna,Alan R. Shuldiner,Steve Sidney,Günther Silbernagel,Blair H. Smith,Blair H. Smith,Jennifer A. Smith,Harold Snieder,Alena Stančáková,Barbara Sternfeld,Amy J. Swift,Tuija Tammelin,Sian-Tsung Tan,Barbara Thorand,Dorothée Thuillier,Liesbeth Vandenput,Henrik Vestergaard,Henrik Vestergaard,Jana V. van Vliet-Ostaptchouk,Marie-Claude Vohl,Uwe Völker,Gérard Waeber,Mark Walker,Sarah H. Wild,Andrew Wong,Alan F. Wright,M. Carola Zillikens,Niha Zubair,Christopher A. Haiman,Loic LeMarchand,Ulf Gyllensten,Claes Ohlsson,Albert Hofman,Albert Hofman,Fernando Rivadeneira,Fernando Rivadeneira,André G. Uitterlinden,Louis Pérusse,James F. Wilson,Caroline Hayward,Ozren Polasek,Francesco Cucca,Kristian Hveem,Catharina A. Hartman,Anke Tönjes,Stefania Bandinelli,Lyle J. Palmer,Sharon L.R. Kardia,Rainer Rauramaa,Thorkild I. A. Sørensen,Jaakko Tuomilehto,Jaakko Tuomilehto,Jaakko Tuomilehto,Veikko Salomaa,Brenda W.J.H. Penninx,Eco J. C. de Geus,Eco J. C. de Geus,Dorret I. Boomsma,Terho Lehtimäki,Massimo Mangino,Massimo Mangino,Markku Laakso,Claude Bouchard,Nicholas G. Martin,Diana Kuh,Yongmei Liu,Allan Linneberg,Allan Linneberg,Winfried März,Winfried März,Winfried März,Konstantin Strauch,Mika Kivimäki,Tamara B. Harris,Vilmundur Gudnason,Henry Völzke,Lu Qi,Marjo-Riitta Järvelin,John C. Chambers,John C. Chambers,John C. Chambers,Jaspal S. Kooner,Jaspal S. Kooner,Jaspal S. Kooner,Philippe Froguel,Philippe Froguel,Charles Kooperberg,Peter Vollenweider,Göran Hallmans,Torben Hansen,Oluf Pedersen,Andres Metspalu,Nicholas J. Wareham,Claudia Langenberg,David R. Weir,David J. Porteous,Eric Boerwinkle,Daniel I. Chasman,Daniel I. Chasman,Daniel I. Chasman,Gonçalo R. Abecasis,Inês Barroso,Inês Barroso,Mark I. McCarthy,Mark I. McCarthy,Timothy M. Frayling,Jeffrey R. O'Connell,Cornelia M. van Duijn,Cornelia M. van Duijn,Michael Boehnke,Iris M. Heid,Karen L. Mohlke,David P. Strachan,Caroline S. Fox,Ching-Ti Liu,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Robert J. Klein,Andrew D. Johnson,Ingrid B. Borecki,Paul W. Franks,Paul W. Franks,Paul W. Franks,Kari E. North,L. Adrienne Cupples,L. Adrienne Cupples,Ruth J. F. Loos,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen,Tuomas O. Kilpeläinen +349 more
TL;DR: In additional genome-wide meta-analyses adjusting for PA and interaction with PA, 11 novel adiposity loci are identified, suggesting that accounting for PA or other environmental factors that contribute to variation in adiposity may facilitate gene discovery.