H
Hannes Hinneburg
Researcher at Macquarie University
Publications - 6
Citations - 100
Hannes Hinneburg is an academic researcher from Macquarie University. The author has contributed to research in topics: Myeloperoxidase & Glycosylation. The author has an hindex of 3, co-authored 6 publications receiving 54 citations.
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Journal ArticleDOI
Protein paucimannosylation is an enriched N-glycosylation signature of human cancers
Sayantani Chatterjee,Ling Y. Lee,Ling Y. Lee,Rebeca Kawahara,Rebeca Kawahara,Jodie L. Abrahams,Jodie L. Abrahams,Barbara Adamczyk,Merrina Anugraham,Merrina Anugraham,Christopher Ashwood,Christopher Ashwood,Zeynep Sumer-Bayraktar,Zeynep Sumer-Bayraktar,Matthew T. Briggs,Jenny H. L. Chik,Jenny H. L. Chik,Arun V. Everest-Dass,Arun V. Everest-Dass,Sarah Förster,Hannes Hinneburg,Katia R. M. Leite,Ian Loke,Ian Loke,Uwe Möginger,Edward S. X. Moh,Miyako Nakano,Miyako Nakano,Saulo Recuero,Manveen K. Sethi,Manveen K. Sethi,Miguel Srougi,Kathrin Stavenhagen,Kathrin Stavenhagen,Vignesh Venkatakrishnan,Katherine Wongtrakul-Kish,Katherine Wongtrakul-Kish,Simone Diestel,Peter Hoffmann,Niclas G. Karlsson,Daniel Kolarich,Mark P. Molloy,Mark P. Molloy,Michael Muders,Martin K. Oehler,Nicolle H. Packer,Nicolle H. Packer,Giuseppe Palmisano,Morten Thaysen-Andersen +48 more
TL;DR: An intriguing association between protein paucimannosylation and human cancers warrants further exploration to detail the biosynthesis, cellular location(s), protein carriers, and functions of paucIMannosidic epitopes in tumorigenesis and metastasis.
Journal ArticleDOI
Hyper-truncated Asn355- and Asn391-glycans modulate the activity of neutrophil granule myeloperoxidase.
Harry C. Tjondro,Julian Ugonotti,Rebeca Kawahara,Sayantani Chatterjee,Ian Loke,Siyun Chen,Fabian Soltermann,Hannes Hinneburg,Benjamin L. Parker,Vignesh Venkatakrishnan,Regis Dieckmann,Oliver C. Grant,Johan Bylund,Alison Rodger,Robert J. Woods,Anna Karlsson-Bengtsson,Anna Karlsson-Bengtsson,Weston B. Struwe,Morten Thaysen-Andersen +18 more
TL;DR: Novel functional roles of MPO glycans are reported, providing new insight into neutrophil-mediated immunity and molecular modelling revealed that hyper-truncated Asn355-glycans positioned in the MPO-ceruloplasmin interface are critical for uninterrupted inhibition.
Journal ArticleDOI
High-resolution longitudinal N- and O-glycoprofiling of human monocyte-to-macrophage transition.
Hannes Hinneburg,Jessica L Pedersen,Nilesh J. Bokil,Alexander Pralow,Falko Schirmeister,Rebeca Kawahara,Erdmann Rapp,Bernadette M. Saunders,Morten Thaysen-Andersen +8 more
TL;DR: This high-resolution glycome map underpinning normal monocyte-to-macrophage transition, the most detailed to date, aids the understanding of the molecular makeup pertaining to two vital innate immune cell types and forms an important reference for future glycoimmunological studies.
Journal ArticleDOI
A pain-causing and paralytic ant venom glycopeptide.
Samuel D. Robinson,Lucas Kambanis,Daniel Clayton,Hannes Hinneburg,Leo Corcilius,Alexander Mueller,Andrew A. Walker,Angelo Keramidas,Sameer S. Kulkarni,Alun Jones,Irina Vetter,Morten Thaysen-Andersen,Richard J. Payne,Richard J. Payne,Glenn F. King,Glenn F. King,Eivind A. B. Undheim +16 more
TL;DR: In this paper, the authors describe the discovery and characterization of an O-linked glycopeptide (Mg7a) as a major component of the venom of the ant Myrmecia gulosa.
Posted ContentDOI
Hyper-Truncated N-Acetyl-β-D-Glucosamine Decorations Augment the Activity and Inhibition Potential of Neutrophil Granule Myeloperoxidase
Harry C. Tjondro,Julian Ugonotti,Rebeca Kawahara,Sayantani Chatterjee,Ian Loke,Siyun Chen,Fabian Soltermann,Hannes Hinneburg,Benjamin L. Parker,Vignesh Venkatakrishnan,Regis Dieckmann,Oliver C. Grant,Johan Bylund,Alison Rodger,Robert J. Woods,Weston B. Struwe,Anna Karlsson-Bengtsson,Morten Thaysen-Andersen +17 more
TL;DR: Native mass spectrometry, mass photometry, and glycopeptide profiling revealed extreme molecular complexity of dimeric nMPO arising from heterogeneous glycosylation, oxidation, chlorination and polypeptide truncation variants, and a lower-abundance monomer, providing new insight into neutrophil glycobiology.