H
Hans Kristian Moen Vollan
Researcher at Oslo University Hospital
Publications - 33
Citations - 3591
Hans Kristian Moen Vollan is an academic researcher from Oslo University Hospital. The author has contributed to research in topics: Breast cancer & Cancer. The author has an hindex of 22, co-authored 29 publications receiving 2904 citations. Previous affiliations of Hans Kristian Moen Vollan include Wellcome Trust Sanger Institute & University of Oslo.
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Journal ArticleDOI
The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes
Bernard Pereira,Suet-Feung Chin,Oscar M. Rueda,Hans Kristian Moen Vollan,Elena Provenzano,Helen Bardwell,Michelle Pugh,Linda Jones,Roslin Russell,Stephen John Sammut,Dana W.Y. Tsui,Bin Liu,Sarah-Jane Dawson,Sarah-Jane Dawson,Jean Abraham,Helen Northen,John F. Peden,Abhik Mukherjee,Gulisa Turashvili,Andrew R. Green,Steve McKinney,Arusha Oloumi,Sohrab P. Shah,Nitzan Rosenfeld,Leigh C. Murphy,David R. Bentley,Ian O. Ellis,Arnie Purushotham,Sarah E Pinder,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale,Helena M. Earl,Paul D.P. Pharoah,Mark T. Ross,Samuel Aparicio,Carlos Caldas +35 more
TL;DR: This study sequence 173 genes in 2,433 primary breast tumours that have copy number aberration, gene expression and long-term clinical follow-up data, and determines associations between mutations, driver CNA profiles, clinical-pathological parameters and survival.
Journal ArticleDOI
Principles and methods of integrative genomic analyses in cancer
Vessela N. Kristensen,Ole Christian Lingjærde,Hege G. Russnes,Hans Kristian Moen Vollan,Arnoldo Frigessi,Anne Lise Børresen-Dale +5 more
TL;DR: The objectives, methods and computational tools of integrative genomics that are available to date are reviewed here, as is their implementation in cancer research.
Journal ArticleDOI
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Sam Behjati,Sam Behjati,Patrick S. Tarpey,Helen Sheldon,Inigo Martincorena,Peter Van Loo,Peter Van Loo,Gunes Gundem,David C. Wedge,Manasa Ramakrishna,Susanna L. Cooke,Nischalan Pillay,Nischalan Pillay,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Elli Papaemmanuil,Hans Koss,Hans Koss,Tom D. Bunney,Claire Hardy,Olivia Joseph,Sancha Martin,Laura Mudie,Adam Butler,Jon W. Teague,M Patil,Graham Steers,Yu Cao,Curtis Gumbs,Davis R. Ingram,Alexander J. Lazar,Latasha Little,Harshad S. Mahadeshwar,Alexei Protopopov,Ghadah A. Al Sannaa,Sahil Seth,Xingzhi Song,Jiabin Tang,Jianhua Zhang,Vinod Ravi,Keila E. Torres,Bhavisha Khatri,Dina Halai,Ioannis Roxanis,Daniel Baumhoer,Roberto Tirabosco,M Fernanda Amary,Chris Boshoff,Chris Boshoff,Ultan McDermott,Matilda Katan,Michael R. Stratton,P. Andrew Futreal,Adrienne M. Flanagan,Adrienne M. Flanagan,Adrian L. Harris,Adrian L. Harris,Peter J. Campbell,Peter J. Campbell +59 more
TL;DR: This work employed whole-genome, whole-exome and targeted sequencing to study the somatic changes underpinning primary and secondary angiosarcoma, and identified recurrent mutations in two genes, PTPRB and PLCG1, which are intimately linked to angiogenesis.
Journal ArticleDOI
Copynumber: Efficient algorithms for single- and multi-track copy number segmentation
Gro Nilsen,Knut Liestøl,Peter Van Loo,Peter Van Loo,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Marianne Brodtkorb Eide,Marianne Brodtkorb Eide,Oscar M. Rueda,Suet-Feung Chin,Roslin Russell,Lars Oliver Baumbusch,Carlos Caldas,Carlos Caldas,Anne Lise Børresen-Dale,Anne Lise Børresen-Dale,Ole Christian Lingjærde,Ole Christian Lingjærde +17 more
TL;DR: The R package copynumber is a software suite for segmentation of single- and multi-track copy number data using algorithms based on coherent least squares principles.
Journal ArticleDOI
TP53 Mutation Spectrum in Breast Cancer Is Subtype Specific and Has Distinct Prognostic Relevance
Laxmi Silwal-Pandit,Hans Kristian Moen Vollan,Suet-Feung Chin,Oscar M. Rueda,Steven McKinney,Tomo Osako,David A. Quigley,Vessela N. Kristensen,Samuel Aparicio,Anne Lise Børresen-Dale,Carlos Caldas,Anita Langerød +11 more
TL;DR: This study reveals that TP53 mutations have different clinical relevance in molecular subtypes of breast cancer, and suggests diverse roles for TP53 in the biology underlying breast cancer development.