V
Vinod Ravi
Researcher at University of Texas MD Anderson Cancer Center
Publications - 140
Citations - 3779
Vinod Ravi is an academic researcher from University of Texas MD Anderson Cancer Center. The author has contributed to research in topics: Sarcoma & Medicine. The author has an hindex of 26, co-authored 115 publications receiving 2708 citations. Previous affiliations of Vinod Ravi include University of Texas at Austin.
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Journal ArticleDOI
Feasibility of Large-Scale Genomic Testing to Facilitate Enrollment Onto Genomically Matched Clinical Trials
Funda Meric-Bernstam,Lauren Brusco,Kenna R. Mills Shaw,Chacha Horombe,Scott Kopetz,Michael A. Davies,Mark J. Routbort,Sarina Anne Piha-Paul,Filip Janku,Naoto T. Ueno,David S. Hong,John de Groot,Vinod Ravi,Yisheng Li,Raja Luthra,Keyur P. Patel,Russell Broaddus,John Mendelsohn,Gordon B. Mills +18 more
TL;DR: Broad implementation of multiplex hotspot testing is feasible; however, only a small portion of patients with actionable alterations were actually enrolled onto genotype-matched trials, and the challenges for trial enrollment are reported.
Journal ArticleDOI
Recurrent PTPRB and PLCG1 mutations in angiosarcoma
Sam Behjati,Sam Behjati,Patrick S. Tarpey,Helen Sheldon,Inigo Martincorena,Peter Van Loo,Peter Van Loo,Gunes Gundem,David C. Wedge,Manasa Ramakrishna,Susanna L. Cooke,Nischalan Pillay,Nischalan Pillay,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Hans Kristian Moen Vollan,Elli Papaemmanuil,Hans Koss,Hans Koss,Tom D. Bunney,Claire Hardy,Olivia Joseph,Sancha Martin,Laura Mudie,Adam Butler,Jon W. Teague,M Patil,Graham Steers,Yu Cao,Curtis Gumbs,Davis R. Ingram,Alexander J. Lazar,Latasha Little,Harshad S. Mahadeshwar,Alexei Protopopov,Ghadah A. Al Sannaa,Sahil Seth,Xingzhi Song,Jiabin Tang,Jianhua Zhang,Vinod Ravi,Keila E. Torres,Bhavisha Khatri,Dina Halai,Ioannis Roxanis,Daniel Baumhoer,Roberto Tirabosco,M Fernanda Amary,Chris Boshoff,Chris Boshoff,Ultan McDermott,Matilda Katan,Michael R. Stratton,P. Andrew Futreal,Adrienne M. Flanagan,Adrienne M. Flanagan,Adrian L. Harris,Adrian L. Harris,Peter J. Campbell,Peter J. Campbell +59 more
TL;DR: This work employed whole-genome, whole-exome and targeted sequencing to study the somatic changes underpinning primary and secondary angiosarcoma, and identified recurrent mutations in two genes, PTPRB and PLCG1, which are intimately linked to angiogenesis.
Journal ArticleDOI
Sorafenib for Advanced and Refractory Desmoid Tumors.
Mrinal M. Gounder,Michelle R. Mahoney,Brian A. Van Tine,Vinod Ravi,Steven Attia,Hari Anant Deshpande,Abha A. Gupta,Mohammed M. Milhem,Robert M. Conry,Sujana Movva,Michael J. Pishvaian,Richard F. Riedel,Tarek Sabagh,William D. Tap,Natally Horvat,Ethan Basch,Lawrence H. Schwartz,Robert G. Maki,Narasimhan P. Agaram,Robert A. Lefkowitz,Yousef Mazaheri,Rikiya Yamashita,John J. Wright,Amylou C. Dueck,Gary K. Schwartz +24 more
TL;DR: Among patients with progressive, refractory, or symptomatic desmoid tumors, sorafenib significantly prolonged progression‐free survival and induced durable responses.
Journal ArticleDOI
Inhibiting the VEGF-VEGFR pathway in angiosarcoma, epithelioid hemangioendothelioma, and hemangiopericytoma/solitary fibrous tumor
TL;DR: Inhibition of the VEGF/VEGFR pathway may be a rational and effective therapy for certain patients with angiosarcoma, EHE, and HPC/SFT, but more studies are needed to confirm these findings and to identify which patients will benefit from these agents.
Journal ArticleDOI
Universal Marker and Detection Tool for Human Sarcoma Circulating Tumor Cells
Arun Satelli,Abhisek Mitra,Jeffry Cutrera,Marcos Devarie,Xueqing Xia,Davis R. Ingram,Denada Dibra,Neeta Somaiah,Keila E. Torres,Vinod Ravi,Joseph A. Ludwig,Eugenie S. Kleinerman,Shulin Li +12 more
TL;DR: The results establish the first universal and specific CTC marker described for enumerating CTCs from different types of sarcoma, thereby providing a key prognosis tool to monitor cancer metastasis and relapse.