H
Harvest F. Gu
Researcher at China Pharmaceutical University
Publications - 21
Citations - 424
Harvest F. Gu is an academic researcher from China Pharmaceutical University. The author has contributed to research in topics: Diabetes mellitus & Insulin resistance. The author has an hindex of 9, co-authored 21 publications receiving 241 citations.
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Journal ArticleDOI
Genome-Wide Association Study of Diabetic Kidney Disease Highlights Biology Involved in Glomerular Basement Membrane Collagen.
Rany M. Salem,Jennifer Todd,Jennifer Todd,Niina Sandholm,Joanne B. Cole,Joanne B. Cole,Wei-Min Chen,Darrell Andrews,Marcus G. Pezzolesi,Paul M. McKeigue,Linda T. Hiraki,Chengxiang Qiu,Viji Nair,Chen Di Liao,Jing Jing Cao,Erkka Valo,Suna Onengut-Gumuscu,Adam M. Smiles,Stuart J. McGurnaghan,Jani K. Haukka,Valma Harjutsalo,Eoin P. Brennan,Natalie R. van Zuydam,Emma Ahlqvist,Ross Doyle,Tarunveer S. Ahluwalia,Maria Lajer,Maria Hughes,Jihwan Park,Jan Skupien,Athina Spiliopoulou,Andrew C. Liu,Rajasree Menon,Carine M. Boustany-Kari,Hyun Min Kang,Robert G. Nelson,Ronald Klein,Barbara E.K. Klein,Kristine E. Lee,Xiaoyu Gao,Michael Mauer,Silvia Maestroni,Maria Luiza Caramori,Ian H. de Boer,Rachel G. Miller,Jingchuan Guo,Andrew P. Boright,David-Alexandre Trégouët,David-Alexandre Trégouët,Beata Gyorgy,Beata Gyorgy,Janet K. Snell-Bergeon,David M. Maahs,Shelley B. Bull,Angelo J. Canty,Colin N. A. Palmer,Lars Stechemesser,Bernhard Paulweber,Raimund Weitgasser,Jelizaveta Sokolovska,Vita Rovīte,Valdis Pīrāgs,Edita Prakapiene,Lina Radzeviciene,Rasa Verkauskiene,Nicolae Mircea Panduru,Nicolae Mircea Panduru,Leif Groop,Leif Groop,Mark I. McCarthy,Harvest F. Gu,Anna Möllsten,Henrik Falhammar,Henrik Falhammar,Kerstin Brismar,Kerstin Brismar,Finian Martin,Peter Rossing,Peter Rossing,Tina Costacou,Gianpaolo Zerbini,Michel Marre,Samy Hadjadj,Amy Jayne McKnight,Carol Forsblom,Gareth J. McKay,Catherine Godson,A. Peter Maxwell,Matthias Kretzler,Katalin Susztak,Helen M. Colhoun,Andrzej S. Krolewski,Andrew D. Paterson,Per-Henrik Groop,Stephen S. Rich,Joel N. Hirschhorn,Joel N. Hirschhorn,Jose C. Florez +97 more
TL;DR: In this paper, a large collection of type 1 diabetes cohorts with harmonized diabetic kidney disease phenotypes were assembled through collaboration with the Diabetes Nephropathy Collaborative Research Initiative, and 16 genome-wide significant risk loci were identified.
Journal ArticleDOI
Genetic and Epigenetic Studies in Diabetic Kidney Disease
TL;DR: Current information from genetic and epigenetic studies of DKD and ESRD in patients with diabetes, including the approaches of genome-wide association study (GWAS) or epigenome-wide associations study (EWAS) and candidate gene association analyses, are summarized.
Journal ArticleDOI
IL-21 Stimulates the expression and activation of cell cycle regulators and promotes cell proliferation in EBV-positive diffuse large B cell lymphoma
Yuxuan Wang,Chengcheng Wang,Cai Xiyunyi,Mou Chang,Cui Xueting,Zhang Yingying,Ge Feng,Hao Dong,Hao Yuanyuan,Cai Lei,Wu Shuting,Feng Chenjie,Chen Jiamin,Jianyong Li,Wei Xu,Lei Fan,Weijia Xie,Tong Yue,Harvest F. Gu,Liang Wu +19 more
TL;DR: Analysis of a rare clinical sample of EBV-positive DLBCL, in combination with a NOD/SCID mouse xenograft model, confirmed the effect of IL-21 on the proliferation of EBv-positiveDLBCL cells and reconfirms the adverse effects of IL
Journal ArticleDOI
Chemical constituents, clinical efficacy and molecular mechanisms of the ethanol extract of Abelmoschus manihot flowers in treatment of kidney diseases.
Nan Li,Nan Li,Haitao Tang,Liang Wu,Haitao Ge,Yurong Wang,Honglin Yu,Xiuli Zhang,Ma Jimei,Harvest F. Gu +9 more
TL;DR: The possible mechanism of Huangkui capsule treatment in kidney diseases may include reducing inflammation and anti‐oxidative stress, improving immune response, protecting renal tubular epithelial cells, ameliorating podocyte apoptosis, glomerulosclerosis and mesangial proliferation, as well as inhibiting renal fibrosis.
Journal ArticleDOI
Protective Effect of the HIF-1A Pro582Ser Polymorphism on Severe Diabetic Retinopathy
Neda Rajamand Ekberg,Sofie Eliasson,Young Wen Li,Young Wen Li,Xiaowei Zheng,Katerina Chatzidionysiou,Henrik Falhammar,Henrik Falhammar,Harvest F. Gu,Sergiu-Bogdan Catrina,Sergiu-Bogdan Catrina +10 more
TL;DR: A protective effect of HIF-1A Pro582Ser against developing severe DR with a risk reduction of 95%, even when adjusting for known risk factors for DR such as diabetes duration, hyperglycemia, and hypertension.