H
Henry D. Mawejje
Researcher at Johns Hopkins University
Publications - 14
Citations - 669
Henry D. Mawejje is an academic researcher from Johns Hopkins University. The author has contributed to research in topics: Anopheles gambiae & Malaria. The author has an hindex of 9, co-authored 10 publications receiving 518 citations. Previous affiliations of Henry D. Mawejje include Liverpool School of Tropical Medicine.
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Journal ArticleDOI
Genetic diversity of the African malaria vector Anopheles gambiae.
Alistair Miles,Alistair Miles,Nicholas J. Harding,Giordano Bottà,Giordano Bottà,Chris S Clarkson,Chris S Clarkson,Tiago Antao,Tiago Antao,Tiago Antao,Krzysztof Kozak,Daniel R. Schrider,Andrew D. Kern,Seth Redmond,Igor V. Sharakhov,Igor V. Sharakhov,Richard D. Pearson,Richard D. Pearson,Christina M. Bergey,Michael C. Fontaine,Martin J. Donnelly,Martin J. Donnelly,Mara K. N. Lawniczak,Diego Ayala,Nora J. Besansky,Austin Burt,Beniamino Caputo,Alessandra della Torre,H. Charles J. Godfray,Matthew W. Hahn,Janet Midega,Daniel E. Neafsey,Samantha M. O’Loughlin,João Pinto,Michelle M. Riehle,Kenneth D. Vernick,David Weetman,Craig S. Wilding,Craig S. Wilding,Bradley J. White,Arlete D. Troco,Abdoulaye Diabaté,Carlo Costantini,Kyanne R. Rohatgi,Nohal Elissa,Boubacar Coulibaly,Joao Dinis,Charles M. Mbogo,Philip Bejon,Henry D. Mawejje,Jim Stalker,Kirk A. Rockett,Eleanor Drury,Daniel Mead,Anna E. Jeffreys,Christina Hubbart,Kate Rowlands,Alison T. Isaacs,Dushyanth Jyothi,Cinzia Malangone,Paul Vauterin,Ben Jeffery,Ian J. Wright,Lee Hart,Krzysztof Kluczynski,Victoria Cornelius,Bronwyn MacInnis,Christa Henrichs,Rachel Giacomantonio,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +70 more
TL;DR: These data revealed complex population structure and patterns of gene flow, with evidence of ancient expansions, recent bottlenecks, and local variation in effective population size.
Journal ArticleDOI
Measures of Malaria Burden after Long-Lasting Insecticidal Net Distribution and Indoor Residual Spraying at Three Sites in Uganda: A Prospective Observational Study.
Agaba Katureebe,Kate Zinszer,Emmanuel Arinaitwe,John Rek,Elijah Kakande,Katia Charland,Ruth Kigozi,Maxwell Kilama,Joaniter I. Nankabirwa,Adoke Yeka,Henry D. Mawejje,Arthur Mpimbaza,Henry Katamba,Martin J. Donnelly,Philip J. Rosenthal,Chris Drakeley,Steve W. Lindsay,Sarah G. Staedke,David L. Smith,Bryan Greenhouse,Moses R. Kamya,Grant Dorsey +21 more
TL;DR: High-quality surveillance evaluated malaria metrics and mosquito exposure before and after interventions through enhanced health-facility-based surveillance to estimate malaria test positivity rate (TPR) and entomology surveys to estimate household-level human biting rate (HBR).
Journal ArticleDOI
Insecticide resistance monitoring of field-collected Anopheles gambiae s.l. populations from Jinja, eastern Uganda, identifies high levels of pyrethroid resistance
Henry D. Mawejje,Craig S. Wilding,Emily J. Rippon,Angela Hughes,David Weetman,Martin J. Donnelly +5 more
TL;DR: PBO synergist bioassays resulted in near complete recovery of pyrethroid susceptibility suggesting involvement of CYP450s in resistance, and hybrids were found, suggesting the possibility of introgression of resistance alleles between species.
Journal ArticleDOI
Contemporary evolution of resistance at the major insecticide target site gene Ace-1 by mutation and copy number variation in the malaria mosquito Anopheles gambiae.
David Weetman,Sara N. Mitchell,Craig S. Wilding,Daniel P. Birks,Alexander E. Yawson,Alexander E. Yawson,John Essandoh,Henry D. Mawejje,Luc Djogbenou,Keith Steen,Emily J. Rippon,Chris S Clarkson,Stuart G. Field,Daniel J. Rigden,Martin J. Donnelly,Martin J. Donnelly +15 more
TL;DR: An unexpected finding is apparently ubiquitous amplification of 119S alleles as part of a large copy number variant (CNV) far exceeding the size of the Ace‐1 gene, whereas 119G alleles were unduplicated.
Journal ArticleDOI
Candidate-gene based GWAS identifies reproducible DNA markers for metabolic pyrethroid resistance from standing genetic variation in East African Anopheles gambiae
David Weetman,Craig S. Wilding,Daniel E. Neafsey,Pie Müller,Pie Müller,Pie Müller,Eric Ochomo,Eric Ochomo,Alison T. Isaacs,Keith Steen,Emily J. Rippon,John C. Morgan,Henry D. Mawejje,Daniel J. Rigden,Loyce M. Okedi,Martin J. Donnelly,Martin J. Donnelly +16 more
TL;DR: This study provides novel, regionally-validated DNA assays for resistance to the most important insecticide class, and establishes both 2La karyotype variation and humidity as common factors impacting the resistance phenotype.