A
Alistair Miles
Researcher at Wellcome Trust Sanger Institute
Publications - 62
Citations - 3700
Alistair Miles is an academic researcher from Wellcome Trust Sanger Institute. The author has contributed to research in topics: Anopheles gambiae & Semantic Web. The author has an hindex of 24, co-authored 60 publications receiving 3135 citations. Previous affiliations of Alistair Miles include Rutherford Appleton Laboratory & Medical Research Council.
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SKOS Simple Knowledge Organization System Reference
Alistair Miles,Sean Bechhofer +1 more
TL;DR: This document defines the Simple Knowledge Organization System (SKOS), a common data model for sharing and linking knowledge organization systems via the Web, which provides a standard, low-cost migration path for porting existing knowledge organizations systems to the Semantic Web.
Journal ArticleDOI
Multiple populations of artemisinin-resistant Plasmodium falciparum in Cambodia
Olivo Miotto,Jacob Almagro-Garcia,Jacob Almagro-Garcia,Jacob Almagro-Garcia,Magnus Manske,Bronwyn MacInnis,Susana Campino,K.A. Rockett,K.A. Rockett,K.A. Rockett,Chanaki Amaratunga,Pharath Lim,Seila Suon,Sokunthea Sreng,Jennifer M. Anderson,Socheat Duong,Chea Nguon,Char Meng Chuor,David S. Saunders,Youry Se,Chantap Lon,Mark M. Fukuda,Lucas Amenga-Etego,Lucas Amenga-Etego,Abraham Hodgson,Victor Asoala,Mallika Imwong,Shannon Takala-Harrison,François Nosten,François Nosten,Xin-zhuan Su,Pascal Ringwald,Frédéric Ariey,Christiane Dolecek,Tran Tinh Hien,Maciej F. Boni,Cao Quang Thai,Alfred Amambua-Ngwa,David J. Conway,David J. Conway,Abdoulaye A. Djimde,Ogobara K. Doumbo,Issaka Zongo,Jean-Bosco Ouédraogo,Daniel Alcock,Eleanor Drury,Sarah Auburn,Oliver O Koch,Mandy Sanders,Christina Hubbart,Gareth Maslen,Valentin Ruano-Rubio,Valentin Ruano-Rubio,Dushyanth Jyothi,Alistair Miles,John O'Brien,Chris Gamble,Samuel O. Oyola,Julian C. Rayner,Chris I. Newbold,Chris I. Newbold,Chris I. Newbold,Matthew Berriman,Chris C. A. Spencer,Gilean McVean,Nicholas P. J. Day,Nicholas P. J. Day,Nicholas J. White,Nicholas J. White,Delia Bethell,Arjen M. Dondorp,Arjen M. Dondorp,Christopher V. Plowe,Rick M. Fairhurst,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +76 more
TL;DR: An analysis of genome variation in 825 P. falciparum samples from Asia and Africa is described that identifies an unusual pattern of parasite population structure at the epicenter of artemisinin resistance in western Cambodia, and a catalog of SNPs that show high levels of differentiation in the art Artemisinin-resistant subpopulations are provided.
Journal ArticleDOI
Genetic diversity of the African malaria vector Anopheles gambiae.
Alistair Miles,Alistair Miles,Nicholas J. Harding,Giordano Bottà,Giordano Bottà,Chris S Clarkson,Chris S Clarkson,Tiago Antao,Tiago Antao,Tiago Antao,Krzysztof Kozak,Daniel R. Schrider,Andrew D. Kern,Seth Redmond,Igor V. Sharakhov,Igor V. Sharakhov,Richard D. Pearson,Richard D. Pearson,Christina M. Bergey,Michael C. Fontaine,Martin J. Donnelly,Martin J. Donnelly,Mara K. N. Lawniczak,Diego Ayala,Nora J. Besansky,Austin Burt,Beniamino Caputo,Alessandra della Torre,H. Charles J. Godfray,Matthew W. Hahn,Janet Midega,Daniel E. Neafsey,Samantha M. O’Loughlin,João Pinto,Michelle M. Riehle,Kenneth D. Vernick,David Weetman,Craig S. Wilding,Craig S. Wilding,Bradley J. White,Arlete D. Troco,Abdoulaye Diabaté,Carlo Costantini,Kyanne R. Rohatgi,Nohal Elissa,Boubacar Coulibaly,Joao Dinis,Charles M. Mbogo,Philip Bejon,Henry D. Mawejje,Jim Stalker,Kirk A. Rockett,Eleanor Drury,Daniel Mead,Anna E. Jeffreys,Christina Hubbart,Kate Rowlands,Alison T. Isaacs,Dushyanth Jyothi,Cinzia Malangone,Paul Vauterin,Ben Jeffery,Ian J. Wright,Lee Hart,Krzysztof Kluczynski,Victoria Cornelius,Bronwyn MacInnis,Christa Henrichs,Rachel Giacomantonio,Dominic P. Kwiatkowski,Dominic P. Kwiatkowski +70 more
TL;DR: These data revealed complex population structure and patterns of gene flow, with evidence of ancient expansions, recent bottlenecks, and local variation in effective population size.
Proceedings Article
SKOS core: simple knowledge organisation for the web
TL;DR: The main purpose of this paper is to provide an initial basis for establishing clear recommendations for the use of SKOS Core and DCMI Metadata Terms in combination.
Journal ArticleDOI
Chloroquine increases Plasmodium falciparum gametocytogenesis in vitro.
TL;DR: A 5-fold increase in gametocytogenesis is demonstrated in the human malaria, P. falciparum, in vitro, in response to treatment with the antimalarial drug chloroquine, and there were clone differences in the relationship between stress and gametocyte production, implying the response was genetically variable.