H
Hiromichi Hamada
Researcher at Chiba University
Publications - 68
Citations - 5406
Hiromichi Hamada is an academic researcher from Chiba University. The author has contributed to research in topics: Kawasaki disease & Endothelial stem cell. The author has an hindex of 29, co-authored 60 publications receiving 4871 citations. Previous affiliations of Hiromichi Hamada include Tufts University & Northwestern University.
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Journal ArticleDOI
Role of TBX1 in human del22q11.2 syndrome
Hisato Yagi,Yoshiyuki Furutani,Hiromichi Hamada,Takashi Sasaki,Shuichi Asakawa,Shinsei Minoshima,Fukiko Ichida,Kunitaka Joo,Misa Kimura,Shin Ichiro Imamura,Naoyuki Kamatani,Kazuo Momma,Atsuyoshi Takao,Makoto Nakazawa,Nobuyoshi Shimizu,Rumiko Matsuoka +15 more
TL;DR: The results suggest that the TBX1 mutation is responsible for five major phenotypes in del22q11.2 syndrome, and conclude thatTBX1 is a major genetic determinant of the del22Q11.
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Clinical Features of Isolated Noncompaction of the Ventricular Myocardium Long-term Clinical Course, Hemodynamic Properties, and Genetic Background
Fukiko Ichida,Yuji Hamamichi,Toshio Miyawaki,Yasuo Ono,Tetsuro Kamiya,Teiji Akagi,Hiromichi Hamada,Osamu Hirose,Takeshi Isobe,Katsuhiko Yamada,Shunji Kurotobi,Hiroshi Mito,Toshiharu Miyake,Yasuo Murakami,Takeshi Nishi,Makoto Shinohara,Masashi Seguchi,Shinjiro Tashiro,Hirofumi Tomimatsu +18 more
TL;DR: In Japanese children, INVM can be found by screening examinations at asymptomatic stage, and it might have a longer dinical course with gradually depressed left ventricular function and restrictive hemodynamics, implying that INVM is a distinctive clinical entity with a heterogeneous genetic background.
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Revision of diagnostic guidelines for Kawasaki disease (the 5th revised edition).
Tohru Kobayashi,Mamoru Ayusawa,Hiroyuki Suzuki,Jun Abe,Shuichi Ito,Taichi Kato,Masahiro Kamada,Junko Shiono,Kenji Suda,Keiji Tsuchiya,Tsuneyuki Nakamura,Yoshikazu Nakamura,Yuichi Nomura,Hiromichi Hamada,Ryuji Fukazawa,Kenji Furuno,Hiroyuki Matsuura,Tomoyo Matsubara,Masaru Miura,Kei Takahashi +19 more
TL;DR: Major alterations are interpretation of cases with 4 or fewer febrile days shortened by early intravenous immunoglobulin treatment, and the clinical importance of atypical (incomplete, or suspected) cases.
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Sonic hedgehog myocardial gene therapy: tissue repair through transient reconstitution of embryonic signaling.
Kengo Fukushima Kusano,Roberto Pola,Toshinori Murayama,Cynthia Curry,Atsuhiko Kawamoto,Atsushi Iwakura,Satoshi Shintani,Masaaki,Jun Asai,Tengiz Tkebuchava,Tina Thorne,Hideya Takenaka,Ryuichi Aikawa,David A. Goukassian,Patrick von Samson,Hiromichi Hamada,Young Sup Yoon,Marcy Silver,Elizabeth Eaton,Hong Ma,Lindsay Heyd,Marianne Kearney,William E. Munger,Jeffery A. Porter,Raj Kishore,Douglas W. Losordo +25 more
TL;DR: Analysis of intramyocardial gene transfer of naked DNA encoding human Shh suggests that Shh gene therapy may have considerable therapeutic potential in individuals with acute and chronic myocardial ischemia by triggering expression of multiple trophic factors and engendering tissue repair in the adult heart.
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A genome-wide association study identifies three new risk loci for Kawasaki disease
Yoshihiro Onouchi,Kouichi Ozaki,Jane C. Burns,Jane C. Burns,Chisato Shimizu,Chisato Shimizu,Masaru Terai,Hiromichi Hamada,Takafumi Honda,Hiroyuki Suzuki,Tomohiro Suenaga,Takashi Takeuchi,Norishige Yoshikawa,Yoichi Suzuki,Kumi Yasukawa,Ryota Ebata,Kouji Higashi,Tsutomu Saji,Yasushi Kemmotsu,Shinichi Takatsuki,Kazunobu Ouchi,Fumio Kishi,Tetsushi Yoshikawa,Toshiro Nagai,Kunihiro Hamamoto,Yoshitake Sato,Akihito Honda,Hironobu Kobayashi,Junichi Sato,Shoichi Shibuta,Masakazu Miyawaki,Ko Oishi,Hironobu Yamaga,Noriyuki Aoyagi,Seiji Iwahashi,Ritsuko Miyashita,Yuji Murata,Kumiko Sasago,Atsushi Takahashi,Naoyuki Kamatani,Michiaki Kubo,Tatsuhiko Tsunoda,Akira Hata,Yusuke Nakamura,Toshihiro Tanaka +44 more
TL;DR: A genome-wide association study of Kawasaki disease in Japanese subjects using data from 428 individuals with Kawasaki Disease and 3,379 controls genotyped at 473,803 SNPs provides new insights into the pathogenesis and pathophysiology of Kaw Osaka disease.