S
Sotirios A. Parashos
Researcher at National Institutes of Health
Publications - 45
Citations - 6442
Sotirios A. Parashos is an academic researcher from National Institutes of Health. The author has contributed to research in topics: SCH-23390 & Population. The author has an hindex of 22, co-authored 42 publications receiving 4980 citations. Previous affiliations of Sotirios A. Parashos include Mayo Clinic & Foundation Center.
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Journal ArticleDOI
Movement Disorder Society-sponsored revision of the Unified Parkinson's Disease Rating Scale (MDS-UPDRS): scale presentation and clinimetric testing results.
Christopher G. Goetz,Barbara C. Tilley,Stephanie R. Shaftman,Glenn T. Stebbins,Stanley Fahn,Pablo Martinez-Martin,Werner Poewe,Cristina Sampaio,Matthew B. Stern,Richard Dodel,Bruno Dubois,Robert G. Holloway,Joseph Jankovic,Jaime Kulisevsky,Anthony E. Lang,Andrew J. Lees,Sue Leurgans,Peter A. LeWitt,David L. Nyenhuis,C. Warren Olanow,Olivier Rascol,Anette Schrag,Jeanne A. Teresi,Jacobus J. van Hilten,Nancy R. LaPelle,Pinky Agarwal,Saima Athar,Yvette Bordelan,Helen Bronte-Stewart,Richard Camicioli,Kelvin L. Chou,Wendy Cole,Arif Dalvi,Holly Delgado,Alan Diamond,Jeremy P.R. Dick,John E. Duda,Rodger J. Elble,Carol Evans,V. G. H. Evidente,Hubert H. Fernandez,Susan H. Fox,Joseph H. Friedman,Robin D. Fross,David A. Gallagher,Deborah A. Hall,Neal Hermanowicz,Vanessa K. Hinson,Stacy Horn,Howard I. Hurtig,Un Jung Kang,Galit Kleiner-Fisman,Olga Klepitskaya,Katie Kompoliti,Eugene C. Lai,Maureen L. Leehey,Iracema Leroi,Kelly E. Lyons,Terry McClain,Steven W. Metzer,Janis M. Miyasaki,John C. Morgan,Martha Nance,Joanne Nemeth,Rajesh Pahwa,Sotirios A. Parashos,Jay S. Schneider,Kapil D. Sethi,Lisa M. Shulman,Andrew Siderowf,Monty Silverdale,Tanya Simuni,Mark Stacy,Robert Malcolm Stewart,Kelly L. Sullivan,David M. Swope,Pettaruse M. Wadia,Richard Walker,Ruth H. Walker,William J. Weiner,Jill Wiener,Jayne R. Wilkinson,Joanna M. Wojcieszek,Summer C. Wolfrath,Frederick Wooten,Allen Wu,Theresa A. Zesiewicz,Richard M. Zweig +87 more
TL;DR: The combined clinimetric results of this study support the validity of the MDS‐UPDRS for rating PD.
Journal ArticleDOI
Inosine to Increase Serum and Cerebrospinal Fluid Urate in Parkinson Disease: A Randomized Clinical Trial
Michael A. Schwarzschild,Alberto Ascherio,M. Flint Beal,Merit Cudkowicz,Gary C. Curhan,Joshua M. Hare,D. Craig Hooper,Karl Kieburtz,Eric A. Macklin,David Oakes,Alice Rudolph,Ira Shoulson,Marsha Tennis,Alberto J. Espay,Maureen Gartner,Albert Y. Hung,Grace Bwala,Richard Lenehan,Elmyra Encarnacion,Melissa Ainslie,Richard Castillo,Daniel M. Togasaki,Gina Barles,Joseph H. Friedman,Lisa Niles,Julie H. Carter,Megan Murray,Christopher G. Goetz,Jeana Jaglin,Anwar Ahmed,David S. Russell,Candace Cotto,John L. Goudreau,Doozie Russell,Sotirios A. Parashos,Patricia Ede,Marie Saint-Hilaire,Cathi-Ann Thomas,Raymond C. James,Mark Stacy,Julia H R Johnson,Lisa Gauger,J. Antonelle de Marcaida,Sheila Thurlow,Stuart Isaacson,Lisbeth Carvajal,Jayaraman Rao,Maureen Cook,Charlise Hope-Porche,Lauren McClurg,Daniela L. Grasso,Robert Logan,Constance Orme,Tori Ross,Alicia Brocht,Radu Constantinescu,Saloni Sharma,Charles S. Venuto,Joseph Weber,Ken Eaton +59 more
TL;DR: Inosine was generally safe, tolerable, and effective in raising serum and cerebrospinal fluid urate levels in early PD and support advancing to more definitive development of inosine as a potential disease-modifying therapy for PD.
Journal ArticleDOI
Falls and injuries resulting from falls among patients with Parkinson's disease and other parkinsonian syndromes
Catherine L. Wielinski,Cordelia Erickson-Davis,Rose Wichmann,Maria Walde‐Douglas,Sotirios A. Parashos +4 more
TL;DR: Further prospective studies will be necessary to elucidate the specific prognostic outcomes of injuries due to falls among parkinsonian patients, and the impact of these injuries on disease progression and quality of life.
Journal ArticleDOI
Effect of Creatine Monohydrate on Clinical Progression in Patients With Parkinson Disease A Randomized Clinical Trial
Karl Kieburtz,Barbara C. Tilley,Jordan J. Elm,Debra Babcock,Robert A. Hauser,G. Webster Ross,Alicia H. Augustine,Erika U. Augustine,Michael J. Aminoff,Ivan Bodis-Wollner,James T. Boyd,Franca Cambi,Kelvin L. Chou,Chadwick W. Christine,Michelle Cines,Nabila Dahodwala,Lorelei Derwent,Richard B. Dewey,Katherine B. Hawthorne,David J. Houghton,Cornelia Kamp,Maureen A. Leehey,Mark F. Lew,Grace S. Liang,Sheng Luo,Zoltan Mari,John C. Morgan,Sotirios A. Parashos,Adriana Pérez,Helen Petrovitch,Suja S. Rajan,Sue Reichwein,Jessie Roth,Jay S. Schneider,Kathleen M. Shannon,David Simon,Tanya Simuni,Carlos Singer,Lewis Sudarsky,Caroline M. Tanner,Chizoba C. Umeh,Karen Williams,Anne-Marie Wills +42 more
TL;DR: Among patients with early and treated Parkinson disease, treatment with creatine monohydrate for at least 5 years, compared with placebo did not improve clinical outcomes, and these findings do not support the use of creatine mon carbohydrate in patients with Parkinson disease.
Journal ArticleDOI
Prominent phenotypic variability associated with mutations in Progranulin
Brendan J. Kelley,Wael N. Haidar,Bradley F. Boeve,Matt Baker,Neill R. Graff-Radford,Thomas A. Krefft,Andrew R. Frank,Clifford R. Jack,Maria Shiung,David S. Knopman,Keith A. Josephs,Sotirios A. Parashos,Rosa Rademakers,Mike Hutton,Stuart Pickering-Brown,Jennifer Adamson,Karen M. Kuntz,Dennis W. Dickson,Joseph E. Parisi,Glenn E. Smith,Robert J. Ivnik,Ronald C. Petersen +21 more
TL;DR: The prominent phenotypic variability within and among eight kindreds evaluated at Mayo Clinic Rochester and/or Mayo Clinic Jacksonville in whom mutations in PGRN were found is described.