I
Inna Gitelman
Researcher at Ben-Gurion University of the Negev
Publications - 20
Citations - 4799
Inna Gitelman is an academic researcher from Ben-Gurion University of the Negev. The author has contributed to research in topics: Twist transcription factor & Gene. The author has an hindex of 12, co-authored 20 publications receiving 4554 citations.
Papers
More filters
Journal ArticleDOI
Twist, a Master Regulator of Morphogenesis, Plays an Essential Role in Tumor Metastasis
Jing Yang,Sendurai A. Mani,Joana Liu Donaher,Sridhar Ramaswamy,Sridhar Ramaswamy,Raphael Itzykson,Christophe Côme,Pierre Savagner,Inna Gitelman,Andrea L. Richardson,Robert A. Weinberg +10 more
TL;DR: A mechanistic link between Twist, EMT, and tumor metastasis is established, suggesting that Twist contributes to metastasis by promoting an epithelial-mesenchymal transition (EMT).
Journal ArticleDOI
A Twist-Snail Axis Critical for TrkB-Induced Epithelial-Mesenchymal Transition-Like Transformation, Anoikis Resistance, and Metastasis
TL;DR: It is demonstrated that TrkB signaling activates a Twist-Snail axis that is critically involved in EMT-like transformation, tumorigenesis, and metastasis, and the data shed more light on the epistatic relationship between Twist and Snail, two key transcriptional regulators of EMT and metastases.
Journal ArticleDOI
Msx2 and Twist cooperatively control the development of the neural crest-derived skeletogenic mesenchyme of the murine skull vault.
Mamoru Ishii,Amy E. Merrill,Yan-Shun Chan,Inna Gitelman,David P. Rice,Henry M. Sucov,Robert E. Maxson +6 more
TL;DR: It is demonstrated that heterozygous loss of Twist function causes a foramen in the skull vault similar to that caused by loss of Msx2 function, and that both the quantity and proliferation of the frontal bone skeletogenic mesenchyme are reduced inMsx2-Twist double mutants compared with individual mutants.
Journal ArticleDOI
Twist Protein in Mouse Embryogenesis
TL;DR: A proposed role of MTwist in somite formation and maturation is inhibition of myogenic bHLH and MEF2 genes and thus prevention of premature and/or ectopic differentiation in the presomitic mesoderm and epithelial somites.
Journal ArticleDOI
Autoregulation of Th1-mediated inflammation by twist1
Uwe Niesner,Inka Albrecht,Marko Janke,Cornelia Doebis,Christoph Loddenkemper,Maria H. Lexberg,Katharina Eulenburg,Stephan Kreher,Juliana Koeck,Ria Baumgrass,Kerstin Bonhagen,Thomas Kamradt,Philipp Enghard,Jens Y Humrich,Sascha Rutz,Ulf Schulze-Topphoff,Orhan Aktas,Sina Bartfeld,Helena Radbruch,Ahmed N. Hegazy,Max Löhning,Daniel C. Baumgart,Rainer Duchmann,Martin Rudwaleit,Thomas Häupl,Inna Gitelman,Veit Krenn,Joachim Gruen,J. Sieper,Martin Zeitz,Bertram Wiedenmann,Frauke Zipp,Alf Hamann,Michal Janitz,Alexander Scheffold,Gerd R Burmester,Hyun D. Chang,Andreas Radbruch +37 more
TL;DR: In this paper, the basic helix-loop-helix transcriptional repressor twist1, as an antagonist of nuclear factor kappaB (NF-kappaB)-dependent cytokine expression, is involved in the regulation of inflammation-induced immunopathology.