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Iradj Sobhani
Researcher at University of Paris
Publications - 138
Citations - 6427
Iradj Sobhani is an academic researcher from University of Paris. The author has contributed to research in topics: Cancer & Colorectal cancer. The author has an hindex of 39, co-authored 128 publications receiving 5403 citations. Previous affiliations of Iradj Sobhani include French Institute of Health and Medical Research & Paris Diderot University.
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Journal ArticleDOI
Potential of fecal microbiota for early‐stage detection of colorectal cancer
Georg Zeller,Julien Tap,Anita Y. Voigt,Shinichi Sunagawa,Jens Roat Kultima,Paul I. Costea,Aurelien Amiot,Jürgen Böhm,Francesco Brunetti,Nina Habermann,Rajna Hercog,Moritz Koch,Alain Luciani,Daniel R. Mende,Martin Schneider,Petra Schrotz-King,Christophe Tournigand,Jeanne Tran Van Nhieu,Takuji Yamada,Jürgen Zimmermann,Vladimir Benes,Matthias Kloor,Matthias Kloor,Matthias Kloor,Cornelia M. Ulrich,Cornelia M. Ulrich,Magnus von Knebel Doeberitz,Magnus von Knebel Doeberitz,Magnus von Knebel Doeberitz,Iradj Sobhani,Peer Bork,Peer Bork +31 more
TL;DR: CRC‐associated changes in the fecal microbiome at least partially reflected microbial community composition at the tumor itself, indicating that observed gene pool differences may reveal tumor‐related host–microbe interactions.
Journal ArticleDOI
Microbial dysbiosis in colorectal cancer (CRC) patients.
Iradj Sobhani,Julien Tap,Françoise Roudot-Thoraval,Jean Pierre Roperch,Sophie Letulle,Philippe Langella,Gérard Corthier,Jeanne Tran Van Nhieu,Jean Pierre Furet +8 more
TL;DR: This is the first large series to demonstrate a composition change in the microbiota of colon cancer patients with possible impact on mucosal immune response and 80% of all sequences could be assigned to a total of 819 taxa based on default parameter of Classifier software.
Journal ArticleDOI
Leptin secretion and leptin receptor in the human stomach
Iradj Sobhani,André Bado,C. Vissuzaine,Marion Buyse,Stéphanie Kermorgant,J.-P. Laigneau,Samir Attoub,Thérèse Lehy,Dominique Hénin,M. Mignon,Miguel J.M. Lewin +10 more
TL;DR: These data provide the first evidence of the presence of leptin and leptin receptor proteins in the human stomach and suggest that gastric epithelial cells may be direct targets for leptin.
Journal ArticleDOI
Extensive transmission of microbes along the gastrointestinal tract.
Thomas Schmidt,Matthew R. Hayward,Luis Pedro Coelho,Simone S. Li,Paul I. Costea,Anita Y. Voigt,Jakob Wirbel,Oleksandr M. Maistrenko,Renato J. Alves,Emma Bergsten,Carine de Beaufort,Iradj Sobhani,Anna Heintz-Buschart,Shinichi Sunagawa,Georg Zeller,Paul Wilmes,Peer Bork +16 more
TL;DR: Evidence is found for a vast majority of oral species to be transferable, with increased levels of transmission in colorectal cancer and rheumatoid arthritis patients and, more generally, for species described as opportunistic pathogens.
Journal ArticleDOI
Are sphincter defects the cause of anal incontinence after vaginal delivery? Results of a prospective study.
Laurent Abramowitz,Iradj Sobhani,R. Ganansia,Albert Vuagnat,Jean Louis Benifla,Emile Daraï,Patrick Madelenat,Michel Mignon +7 more
TL;DR: The aims of the present study were to determine prospectively the incidence of anal incontinence and anal sphincter damage after childbirth and their relationship with obstetric parameters, and to discuss surgical repair in symptomatic patients.