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Matthew R. Hayward
Researcher at Ragon Institute of MGH, MIT and Harvard
Publications - 20
Citations - 1165
Matthew R. Hayward is an academic researcher from Ragon Institute of MGH, MIT and Harvard. The author has contributed to research in topics: Microbiome & Metagenomics. The author has an hindex of 8, co-authored 16 publications receiving 693 citations. Previous affiliations of Matthew R. Hayward include Animal and Plant Health Agency & Royal Holloway, University of London.
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Journal ArticleDOI
Towards standards for human fecal sample processing in metagenomic studies
Paul I. Costea,Georg Zeller,Shinichi Sunagawa,Eric Pelletier,Eric Pelletier,Adriana Alberti,Florence Levenez,Melanie Tramontano,Marja Driessen,Rajna Hercog,Ferris Elias Jung,Jens Roat Kultima,Matthew R. Hayward,Luis Pedro Coelho,Emma Allen-Vercoe,Laurie Bertrand,Michael Blaut,Jillian R.M. Brown,Thomas Carton,Stéphanie Cools-Portier,Michelle C. Daigneault,Muriel Derrien,Anne Druesne,Willem M. de Vos,Willem M. de Vos,B. Brett Finlay,Harry J. Flint,Francisco Guarner,Masahira Hattori,Masahira Hattori,Hans G.H.J. Heilig,Ruth Ann Luna,Johan E. T. van Hylckama Vlieg,Jana Junick,Ingeborg Klymiuk,Philippe Langella,Volker Mai,Chaysavanh Manichanh,Jennifer C. Martin,Clémentine Mery,Hidetoshi Morita,Paul W. O'Toole,Céline Orvain,Kiran Raosaheb Patil,John Penders,Søren Persson,Nicolas Pons,Milena Popova,Anne Salonen,Delphine M. Saulnier,Karen P. Scott,Bhagirath Singh,Kathleen Slezak,Patrick Veiga,James Versalovic,Liping Zhao,Erwin G. Zoetendal,S. Dusko Ehrlich,S. Dusko Ehrlich,Joël Doré,Peer Bork +60 more
TL;DR: A standardized DNA extraction method for human fecal samples is recommended, for which transferability across labs was established and which was further benchmarked using a mock community of known composition to improve comparability of human gut microbiome studies and facilitate meta-analyses.
Journal ArticleDOI
Extensive transmission of microbes along the gastrointestinal tract.
Thomas Schmidt,Matthew R. Hayward,Luis Pedro Coelho,Simone S. Li,Paul I. Costea,Anita Y. Voigt,Jakob Wirbel,Oleksandr M. Maistrenko,Renato J. Alves,Emma Bergsten,Carine de Beaufort,Iradj Sobhani,Anna Heintz-Buschart,Shinichi Sunagawa,Georg Zeller,Paul Wilmes,Peer Bork +16 more
TL;DR: Evidence is found for a vast majority of oral species to be transferable, with increased levels of transmission in colorectal cancer and rheumatoid arthritis patients and, more generally, for species described as opportunistic pathogens.
Journal ArticleDOI
Similarity of the dog and human gut microbiomes in gene content and response to diet
Luis Pedro Coelho,Jens Roat Kultima,Paul I. Costea,Coralie Fournier,Yuanlong Pan,Gail Czarnecki-Maulden,Matthew R. Hayward,Sofia K. Forslund,Thomas Schmidt,Patrick Descombes,Janet R. Jackson,Qinghong Li,Peer Bork,Peer Bork +13 more
TL;DR: Findings in dogs may be predictive of human microbiome results, and a novel finding is that overweight or obese dogs experience larger compositional shifts than lean dogs in response to a high-protein diet.
Journal ArticleDOI
Comparative genomics of Salmonella enterica serovars Derby and Mbandaka, two prevalent serovars associated with different livestock species in the UK.
TL;DR: Comparative functional genomics using the RAST annotation system showed that predominantly mechanisms that relate to metabolite utilisation, in vivo and ex vivo persistence and pathogenesis distinguish S. Derby from S. Mbandaka, suggesting these two serovars have been exposed to different stresses.
Journal ArticleDOI
Population structure and associated phenotypes of Salmonella enterica serovars Derby and Mbandaka overlap with host range
Matthew R. Hayward,Matthew R. Hayward,Liljana Petrovska,Vincent A. A. Jansen,Martin J. Woodward +4 more
TL;DR: The results of this study lend support to the hypothesis that the differences in host ranges of S. Derby and S. Mbandaka are adaptations to pathogenesis, environmental persistence, as well as utilisation of metabolites abundant in their respective host environments.