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James H. Eubanks

Researcher at University Health Network

Publications -  112
Citations -  4864

James H. Eubanks is an academic researcher from University Health Network. The author has contributed to research in topics: Hippocampal formation & Epilepsy. The author has an hindex of 34, co-authored 108 publications receiving 4392 citations. Previous affiliations of James H. Eubanks include University of California, San Diego & Salk Institute for Biological Studies.

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Base-Resolution Analyses of Sequence and Parent-of-Origin Dependent DNA Methylation in the Mouse Genome

Wei Xie, +9 more
- 17 Feb 2012 - 
TL;DR: A base-resolution, allele-specific DNA methylation map in the mouse genome is generated, finding parent-of-origin dependent (imprinted) ASM at 1,952 CG dinucleotides and a surprising presence of non-CG methylation in the adult mouse brain, with some showing evidence of imprinting.
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Hippocampal synaptic plasticity is impaired in the Mecp2-null mouse model of Rett syndrome.

Yukiko Asaka, +4 more
- 01 Jan 2006 - 
TL;DR: Together, these data provide the first evidence that the loss of Mecp2 expression is accompanied by age-dependent alterations in excitatory synaptic plasticity that are likely to contribute to the cognitive and functional deficits underlying Rett syndrome.
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ATRX Partners with Cohesin and MeCP2 and Contributes to Developmental Silencing of Imprinted Genes in the Brain

Kristin D. Kernohan, +7 more
- 16 Feb 2010 - 
TL;DR: It is proposed that ATRX, cohesin, and MeCP2 cooperate to silence a subset of imprinted genes in the postnatal mouse brain.
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Preclinical research in Rett syndrome: Setting the foundation for translational success

David M. Katz, +20 more
- 01 Nov 2012 - 
TL;DR: A comprehensive summary of the physiological and behavioral phenotypes of RTT mouse models to date and areas in which further phenotypic analyses are required to enhance the utility of these models for translational studies are summarized.
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The expression of methyl CpG binding factor MeCP2 correlates with cellular differentiation in the developing rat brain and in cultured cells

Benjamin Jung, +8 more
- 01 Apr 2003 - 
TL;DR: Support for a role for MeCP2 in the establishment and/or maintenance of neuronal maturity is supported, where Western blot analysis during the in vitro differentiation of PC12, NG108-15, and SH-SY5Y cells revealed that Me CP2 levels increased as the cells acquired a more differentiated phenotype.