J
Jan F. C. Glatz
Researcher at Maastricht University
Publications - 309
Citations - 20133
Jan F. C. Glatz is an academic researcher from Maastricht University. The author has contributed to research in topics: Fatty acid & CD36. The author has an hindex of 72, co-authored 304 publications receiving 18662 citations. Previous affiliations of Jan F. C. Glatz include Maastricht University Medical Centre & Leiden University Medical Center.
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Journal ArticleDOI
Comparison of perfusate activities of glutathione S-transferase, alanine aminopeptidase and fatty acid binding protein in the assessment of non-heart-beating donor kidneys
Muhammed A. Gok,Maurice M.A.L. Pelsers,Jan F. C. Glatz,Aftab A. Bhatti,Brian K. Shenton,R. Peaston,C Cornell,Dave Mantle,David Talbot +8 more
TL;DR: In this study, GST, Ala-AP and FABP represent equivalent biochemical markers in terms of their ability to quantitate renal tissue injury in human NHBD kidneys, and there may be some advantage in using all three analytes to provide complementary information on kidney allograft viability.
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Skeletal muscle fatty acid transporter protein expression in type 2 diabetes patients compared with overweight, sedentary men and age-matched, endurance-trained cyclists.
Maurice M.A.L. Pelsers,Kostas Tsintzas,Hanneke Boon,K. Jewell,Luke Norton,Joost J. F. P. Luiken,Jan F. C. Glatz,L.J.C. van Loon +7 more
TL;DR: Membrane fatty acid transporters can modulate the balance between fatty acid uptake and subsequent storage and/or oxidation in muscle tissue and could play an important role in the etiology of insulin resistance and/ or type 2 diabetes.
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Fatty acids in cell signaling: Historical perspective and future outlook
TL;DR: Manipulating fatty acid availability holds promise as therapeutic approach for chronic diseases that are characterized by a perturbed fatty acid metabolism.
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Metabolic Profiling Associates with Disease Severity in Nonischemic Dilated Cardiomyopathy
Job Verdonschot,Ping Wang,Marc van Bilsen,Mark R. Hazebroek,Jort J. Merken,Els K. Vanhoutte,Michiel T H M Henkens,Arthur van den Wijngaard,Jan F. C. Glatz,Ingrid P.C. Krapels,Han G. Brunner,Stephane Heymans,Jörgen Bierau +12 more
TL;DR: The metabolic profile can complement NT-proBNP in determining disease severity in non-ischemic dilated cardiomyopathy and reveal potential alternative treatment targets in advanced symptomatic DCM.
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Heart-type fatty acid binding protein (H-FABP) in patients in an emergency department setting, suspected of acute coronary syndrome: Optimal cut-off point, diagnostic value and future opportunities in primary care
Robert Willemsen,Evie van Severen,Pieter M. Vandervoort,Lars Grieten,Frank Buntinx,Jan F. C. Glatz,Geert-Jan Dinant +6 more
TL;DR: In patients presenting chest pain, plasma H-FABP reaches the highest diagnostic value when a cut-off value of 4 ng/ml is used, and diagnostic values of an algorithm combining point-of-care H-fABP measurement and a score of signs and symptoms should be studied in primary care to learn if such an algorithm could safely reduce referral rate by GPs.