J
Jan F. C. Glatz
Researcher at Maastricht University
Publications - 309
Citations - 20133
Jan F. C. Glatz is an academic researcher from Maastricht University. The author has contributed to research in topics: Fatty acid & CD36. The author has an hindex of 72, co-authored 304 publications receiving 18662 citations. Previous affiliations of Jan F. C. Glatz include Maastricht University Medical Centre & Leiden University Medical Center.
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Journal ArticleDOI
Good and bad consequences of altered fatty acid metabolism in heart failure: evidence from mouse models
Desiree Abdurrachim,Joost J. F. P. Luiken,Klaas Nicolay,Jan F. C. Glatz,Jeanine J. Prompers,Miranda Nabben +5 more
TL;DR: Whether and when modulations in FA metabolism are protective against heart failure are discussed, based on studies in which mouse models were exposed to ischaemic and non-ischaemic heart failure.
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Metabolic challenges reveal impaired fatty acid metabolism and translocation of FAT/CD36 but not FABPpm in obese Zucker rat muscle.
Xiao-Xia Han,Adrian Chabowski,Narendra N. Tandon,Jorge Calles-Escandon,Jan F. C. Glatz,Joost J. F. P. Luiken,Arend Bonen +6 more
TL;DR: In this paper, the translocation of the fatty acid transporter FAT/CD36 and plasma membrane-associated fatty acid binding protein (FABPpm) in obese rat muscle was examined, in muscle of lean and obese Zucker rats.
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Subcellular trafficking of the substrate transporters GLUT4 and CD36 in cardiomyocytes.
Laura K.M. Steinbusch,Robert W. Schwenk,D. Margriet Ouwens,Michaela Diamant,Jan F. C. Glatz,Joost J. F. P. Luiken +5 more
TL;DR: Transmission components of proteins involved in trafficking of cargo between subcellular compartments, which are differently involved in GLUT4 or CD36 translocation, may be considered novel targets for the development of therapies to restore the imbalanced substrate utilization in obesity, insulin resistance and diabetic cardiomyopathy.
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Gender-Related Differences in the Metabolic Response to Fasting
Maarten R. Soeters,Hans P. Sauerwein,Johanna E. M. Groener,Johannes M. F. G. Aerts,Mariëtte T. Ackermans,Jan F. C. Glatz,Eric Fliers,Mireille J. Serlie +7 more
TL;DR: It is suggested that during fasting, women are relatively protected from FFA-induced insulin resistance by preventing myocellular accumulation of ceramide.
Journal ArticleDOI
Influence of age and sex and day-to-day and within-day biological variation on plasma concentrations of fatty acid-binding protein and myoglobin in healthy subjects.
Maurice M.A.L. Pelsers,Jean-Paul Chapelle,Marjo H. J. Knapen,Cees Vermeer,Arno M. M. Muijtjens,Wim Th. Hermens,Jan F. C. Glatz +6 more
TL;DR: The aim of the present study was to establish parameters for FABP first in a large group of volunteers of different ages and to delineate possible effects of age and sex on the ratio of the plasma concentrations of Mb over FABp.