J
Jan F. C. Glatz
Researcher at Maastricht University
Publications - 309
Citations - 20133
Jan F. C. Glatz is an academic researcher from Maastricht University. The author has contributed to research in topics: Fatty acid & CD36. The author has an hindex of 72, co-authored 304 publications receiving 18662 citations. Previous affiliations of Jan F. C. Glatz include Maastricht University Medical Centre & Leiden University Medical Center.
Papers
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Journal ArticleDOI
Heart fatty acid binding protein and cardiac troponin T plasma concentrations as markers for myocardial infarction after coronary artery ligation in mice.
Wendy M. Aartsen,Maurice M.A.L. Pelsers,Wim Th. Hermens,Jan F. C. Glatz,Mat J.A.P. Daemen,Jos F.M. Smits +5 more
TL;DR: Testing whether plasma concentrations of heart-type fatty acid-binding protein (H-FABP) and/or cardiac troponin T (cTnT) discriminate between infarcted and sham-operated mice and allow estimation of infarCT size found it can be used to distinguish MI from sham mice.
Journal ArticleDOI
Use of two biomarkers of renal ischemia to assess machine-perfused non-heart-beating donor kidneys.
Muhammed A. Gok,Maurice M.A.L. Pelsers,Jan F. C. Glatz,BK Shenton,R Peaston,Chris Cornell,David Talbot +6 more
TL;DR: Original work by the Maastricht NHBD group has established threshold limits for tGST activity in kidney perfusates for the selection of “viable” kidneys for transplantation, and this criterion has been introduced in Newcastle, England, where 69 NHBD renal transplants have …
Journal ArticleDOI
Stable transfection of fatty acid translocase (CD36) in a rat heart muscle cell line (H9c2).
Frans A. van Nieuwenhoven,Joost J. F. P. Luiken,Yvonne F. de Jong,Paul Grimaldi,Ger J. van der Vusse,Jan F. C. Glatz +5 more
TL;DR: It is found that palmitate uptake by H9c2 cells occurs mainly by passive diffusion, raising the possibility that H9C2 cells lack a protein (or set of proteins) that acts as an obligatory partner of FAT in long-chain fatty acid transport from the extracellular compartment to the cytoplasm.
Journal ArticleDOI
Signalling components involved in contraction-inducible substrate uptake into cardiac myocytes.
TL;DR: The unravelling of further components along this contraction pathway can provide valuable information on the coordinated regulation of the uptake of glucose and of LCFA by an increase in mechanical activity of heart and skeletal muscle.
Book ChapterDOI
Intracellular transport of fatty acids in muscle. Role of cytoplasmic fatty acid-binding protein.
TL;DR: The facilitation of intracellular fatty acid transport by FABPc is accomplished by increasing the concentration of the diffusing fatty acids in the aqueous cytoplasm and, most likely, by interacting directly with membranes to promote transfer of fatty acids to and from the cytosolic binding protein.