J
Jan F. C. Glatz
Researcher at Maastricht University
Publications - 309
Citations - 20133
Jan F. C. Glatz is an academic researcher from Maastricht University. The author has contributed to research in topics: Fatty acid & CD36. The author has an hindex of 72, co-authored 304 publications receiving 18662 citations. Previous affiliations of Jan F. C. Glatz include Maastricht University Medical Centre & Leiden University Medical Center.
Papers
More filters
Journal ArticleDOI
Insulin-induced translocation of CD36 to the plasma membrane is reversible and shows similarity to that of GLUT4.
Masja M van Oort,Jan M. Van Doorn,Arend Bonen,Jan F. C. Glatz,Dick J. Van der Horst,Kees W. Rodenburg,Joost J.F.P. Luiken,Joost J.F.P. Luiken +7 more
TL;DR: This study is the first to present morphological evidence for CD36 translocation, and shows this process to resemble GLUT4 translocation.
Book ChapterDOI
Transport of Long-Chain Fatty Acids across the Muscular Endothelium
Ger J. van der Vusse,Jan F. C. Glatz,Frans A. van Nieuwenhoven,Robert S. Reneman,James B. Bassingthwaighte +4 more
TL;DR: Kinetic studies have revealed that interaction of the albumin-fatty acid complex with the endothelial membrane may accelerate the dissociation of the complex, which facilitates the uptake of fatty acids by the endothelium, and plasmalemmal fatty acid-binding protein (FABPpm), fatty acid translocase (FAT) and fatty acids-transport protein (fATP) are putatively involved in transmembrane movement of the fatty acid molecules.
Journal ArticleDOI
Intracellular transport of lipids.
TL;DR: H-FABP was found to modulate cardiac energy production by controlling the transfer of acyl-L-carnitine to the mitochondrial β-oxidative system and may also protect the heart against the toxic effects of high intracellular levels of fatty acid intermediates that arise during ischemia.
Journal ArticleDOI
Cardiac and skeletal muscle fatty acid transport and transporters and triacylglycerol and fatty acid oxidation in lean and Zucker diabetic fatty rats.
Arend Bonen,Graham P. Holloway,Narendra N. Tandon,Xiao-Xia Han,Jay T. McFarlan,Jan F. C. Glatz,Joost J. F. P. Luiken +6 more
TL;DR: In red, but not white, muscle of insulin-resistant and type 2 diabetic animals, a marked upregulation in fatty acid transport and intramuscular triacylglycerol was associated with increased levels of FAT/CD36 expression and plasmalemmal content.
Journal ArticleDOI
A sandwich enzyme linked immuno-sorbent assay for the determination of rat heart fatty acid-binding protein using the streptavidin-biotin system. Application to tissue and effluent samples from normoxic rat heart perfusion.
TL;DR: Findings suggest that during normoxic perfusion of rat heart H-FABPc, and LDH are released from different cellular compartments and that the bulk amount of released intracellular proteins is transported via the lymph instead of being directly released into the bloodstream.