Alexander Harms

TL;DR: Scientists working on the response of bacteria to antibiotics define antibiotic persistence and provide practical guidance on how to study bacterial persister cells, and provide a guide to measuring persistence.

TL;DR: The results confirm the long-standing notion that persistence is intimately connected to slow growth or dormancy in the sense that a certain level of physiological quiescence is attained and offer insights into the molecular basis and control of bacterial persistence.

TL;DR: How multiple levels of regulation shape the conditions of toxin activation to achieve the different biological functions of TA modules is highlighted.

TL;DR: Current knowledge on the molecular processes underlying both the infection strategy and pathogenesis of Bartonella are compiled and their connection to the clinical presentation of human patients is discussed, which ranges from minor complaints to life-threatening disease.

TL;DR: The model of persister formation is used as a model to critically examine common experimental procedures to understand and overcome the inconsistencies often observed between results of different laboratories and the results show that seemingly simple antibiotic killing assays are very sensitive to variations in culture conditions and bacterial growth phase.