抗原变异可使得多种致病微生物易于逃避宿主免疫应答。表达在感染红细胞表面的恶性疟原虫红细胞表面蛋白1（PfPMP1）与感染红细胞、内皮细胞、树突状细胞以及胎盘的单个或多个受体作用，在黏附及免疫逃避中起关键的作用。每个单倍体基因组var基因家族编码约60种成员，通过启动转录不同的var基因变异体为抗原变异提供了分子基础。

疟原虫var基因转换速率变化导致抗原变异[英]／Paul H, Robert P, Christodoulou Z, et al//Proc Natl Acad Sci U S A

Deposits of clastic carbonate-dominated (calciclastic) sedimentary slope systems in the rock record have been identified mostly as linearly-consistent carbonate apron deposits, even though most ancient clastic carbonate slope deposits fit the submarine fan systems better. Calciclastic submarine fans are consequently rarely described and are poorly understood. Subsequently, very little is known especially in mud-dominated calciclastic submarine fan systems. Presented in this study are a sedimentological core and petrographic characterisation of samples from eleven boreholes from the Lower Carboniferous of Bowland Basin (Northwest England) that reveals a >250 m thick calciturbidite complex deposited in a calciclastic submarine fan setting. Seven facies are recognised from core and thin section characterisation and are grouped into three carbonate turbidite sequences. They include: 1) Calciturbidites, comprising mostly of highto low-density, wavy-laminated bioclast-rich facies; 2) low-density densite mudstones which are characterised by planar laminated and unlaminated muddominated facies; and 3) Calcidebrites which are muddy or hyper-concentrated debrisflow deposits occurring as poorly-sorted, chaotic, mud-supported floatstones. These

Phd by thesis

Lanthanide-based luminescent hybrid materials.

Optical Waveguide Theory

Recent developments in rare-earth doped materials for optoelectronics

There are presented optical properties of strongly in-plane elongated nanostructures the so called quantum dashes made in InAs/InP material system by molecular beam epitaxy. They have been investigated systematically by a spectroscopic manner on both the entire ensemble and on the single dash level. Their properties are discussed with respect to the fundamental electronic and optical properties as the polarization of emission and the corresponding driving factors, exciton fine structure splitting, biexciton binding energy, the characteristic exciton to biexciton lifetimes ratio and exciton decoherence via interaction with acoustic phonons. The experimental results are analyzed supported by previous energy level calculations within the eight-band kp theory and the rate equation modeling of the exciton kinetics.

Optical Properties of Quantum Dashes

We report on detailed investigations of low temperature ( T=2 K ) polarisation-resolved photoluminescence from heavily doped p-type Ga1−xAlxAs/GaAs single heterojunctions in magnetic field up to 23 T applied perpendicular to the structure. The unbound and the exciton bound transitions of photoexcited electrons with 2D holes were observed. The problem of free and localised charged exitons was discussed. The experimental data were compared with detailed numerical calculations.

Magnetic-field-induced excitons in photoluminescence from heavily doped p-type Ga1−xAlxAs/GaAs single heterojunction

Photoluminescence of quaternary manganese based semimagnetic semiconductors

The composites with various terbium concentrations are synthesized in the silicon-based porous anodic alumina by the coprecipitation method from solutions of yttrium, aluminum and terbium nitrates. The photoluminescence of these structures is investigated. It is found that the yttrium aluminum composite obtained from the solution with terbium concentration 0.1 mol.% demonstrates the most intensive photoluminescence in the green range. The terbium related photoluminescence intensity decreases with a further increase in the concentration of terbium.

Photoluminescence of the yttrium aluminum composites doped with various concentrations of terbium

Photoreflectance spectroscopy as the nondestructive, contactless, room temperature method to investigate semiconductor layers, interfaces, structures and devices is presented. Principles of the method are described. Application to the investigations of the III-V and II-VI compounds structures, including quantum wells, heterojunction bipolar transistors, high electron mobility transistors, vertical cavity surface emitting lasers and quantum dots arrays are shown.© (1997) COPYRIGHT SPIE--The International Society for Optical Engineering. Downloading of the abstract is permitted for personal use only.

Jan Misiewicz

Papers

Optical Properties of Quantum Dashes

Magnetic-field-induced excitons in photoluminescence from heavily doped p-type Ga1−xAlxAs/GaAs single heterojunction

Photoluminescence of quaternary manganese based semimagnetic semiconductors

Photoluminescence of the yttrium aluminum composites doped with various concentrations of terbium

Photoreflectance spectroscopy for investigations of semiconductor structures