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Jean-Christophe Lagier

Researcher at Aix-Marseille University

Publications -  311
Citations -  17625

Jean-Christophe Lagier is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Genome & Medicine. The author has an hindex of 50, co-authored 274 publications receiving 13861 citations. Previous affiliations of Jean-Christophe Lagier include Institut de recherche pour le développement & Centre national de la recherche scientifique.

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A polyphasic strategy incorporating genomic data for the taxonomic description of novel bacterial species

TL;DR: The pros and cons of genome sequencing for taxonomy are reviewed and it is proposed that the incorporation of genome sequences in taxonomic studies has the advantage of using reliable and reproducible data.
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Autoantibodies neutralizing type I IFNs are present in ~ 4% of uninfected individuals over 70 years old and account for ~ 20% of COVID-19 deaths.

Paul Bastard, +58 more
- 19 Aug 2021 - 
TL;DR: In this paper, the authors found that auto-antibodies neutralizing high concentrations (10 ng/mL, in plasma diluted 1 to 10) of IFN-α and/or -ω are found in about 10% of patients with critical COVID-19 pneumonia, but not in subjects with asymptomatic infections.
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Human Gut Microbiota: Repertoire and Variations

TL;DR: A considerable limitation to the interpretation of studies of human gut microbiota is associated with funding sources and transparency disclosures, and studies independent of food industry funding and using complementary methods from a broad range of both culture-based and molecular tools will increase knowledge of the repertoire of this complex ecosystem and host-microbiota mutualism.
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Gut bacterial microbiota and obesity

TL;DR: The studies describing the associations between the microbiota composition, its manipulation, and obesity are reviewed to propose mechanisms linking the microbiota to fat content and weight.