J
Jeanne M. Clark
Researcher at Johns Hopkins University School of Medicine
Publications - 261
Citations - 31356
Jeanne M. Clark is an academic researcher from Johns Hopkins University School of Medicine. The author has contributed to research in topics: Type 2 diabetes & Weight loss. The author has an hindex of 68, co-authored 229 publications receiving 26900 citations. Previous affiliations of Jeanne M. Clark include Johns Hopkins University.
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Journal ArticleDOI
Long-term effects of a lifestyle intervention on weight and cardiovascular risk factors in individuals with type 2 diabetes mellitus: four-year results of the Look AHEAD trial.
Rena R. Wing,Judy Bahnson,George A. Bray,Jeanne M. Clark,Mace Coday,Caitlin Egan,Mark A. Espeland,John P. Foreyt,Edward W. Gregg,Valerie Goldman,Steven M. Haffner,Helen P. Hazuda,James O. Hill,Edward S. Horton,Van S. Hubbard,John M. Jakicic,Robert W. Jeffery,Karen C. Johnson,Steven E. Kahn,Tina Killean,Abbas E. Kitabchi,Cora E. Lewis,Cathy Manus,Barbara J. Maschak-Carey,Sara Michaels,Maria G. Montez,Brenda Montgomery,David M. Nathan,Jennifer Patricio,Anne L. Peters,Xavier Pi-Sunyer,Henry J. Pownall,David M. Reboussin,W. Jack Rejeski,Richard R. Rubin,Monika M. Safford,Tricia Skarphol,Brent Van Dorsten,Thomas A. Wadden,Lynne E. Wagenknecht,Jacqueline Wesche-Thobaben,Delia S. West,Donald A. Williamson,Susan Z. Yanovski +43 more
TL;DR: Intensive lifestyle intervention can produce sustained weight loss and improvements in fitness, glycemic control, and CVD risk factors in individuals with type 2 diabetes.
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Diagnostic accuracy and reliability of ultrasonography for the detection of fatty liver: A meta‐analysis
Ruben Hernaez,Ruben Hernaez,Mariana Lazo,Susanne Bonekamp,Ihab R. Kamel,Frederick L. Brancati,Eliseo Guallar,Jeanne M. Clark +7 more
TL;DR: Ultrasonography allows for reliable and accurate detection of moderate‐severe fatty liver, compared to histology, and is likely the imaging technique of choice for screening for fatty liver in clinical and population settings.
Journal ArticleDOI
Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: The TONIC Randomized Controlled Trial
Joel E. Lavine,Jeffrey B. Schwimmer,Mark L. Van Natta,Jean P. Molleston,Jean P. Molleston,Karen F. Murray,Philip J. Rosenthal,Stephanie H. Abrams,Ann O. Scheimann,Arun J. Sanyal,Naga Chalasani,James Tonascia,Aynur Unalp,Jeanne M. Clark,Elizabeth M. Brunt,David E. Kleiner,Jay H. Hoofnagle,Patricia R. Robuck +17 more
TL;DR: Neither vitamin E nor metformin was superior to placebo in attaining the primary outcome of sustained reduction in ALT level in patients with pediatric NAFLD.
Journal ArticleDOI
Nonalcoholic fatty liver disease
TL;DR: A review of the clinical literature and selected basic information about NAFLD challenges some of the assumptions about the clinical importance of the disease.
Journal ArticleDOI
Genome-wide association analysis identifies variants associated with nonalcoholic fatty liver disease that have distinct effects on metabolic traits
Elizabeth K. Speliotes,Laura M. Yerges-Armstrong,Jun Wu,Ruben Hernaez,Ruben Hernaez,Lauren J. Kim,Cameron D. Palmer,Vilmundur Gudnason,Gudny Eiriksdottir,Melissa E. Garcia,Lenore J. Launer,Mike A. Nalls,Jeanne M. Clark,Braxton D. Mitchell,Alan R. Shuldiner,Alan R. Shuldiner,Johannah L. Butler,Johannah L. Butler,Marta Tomas,Udo Hoffmann,Shih-Jen Hwang,Joseph M. Massaro,Joseph M. Massaro,Christopher J. O'Donnell,Christopher J. O'Donnell,Dushyant V. Sahani,Veikko Salomaa,Eric E. Schadt,Stephen M. Schwartz,David S. Siscovick,Nash Crn,Magic Investigators,Benjamin F. Voight,J. Jeffrey Carr,Mary F. Feitosa,Tamara B. Harris,Caroline S. Fox,Albert V. Smith,W. H. Linda Kao,Joel N. Hirschhorn,Joel N. Hirschhorn,Joel N. Hirschhorn,Ingrid B. Borecki +42 more
TL;DR: In this article, a fixed-effects meta-analysis of genome-wide association (GWA) results between CT hepatic steatosis and 2.4 million imputed or genotyped SNPs in 7,176 individuals from the Old Order Amish, Age, Gene/Environment Susceptibility-Reykjavik study (AGES), Family Heart, and Framingham Heart Studies (n = 880 to 3,070).