Jeffrey Raizer

TL;DR: GABA(B) receptor autoimmune encephalitis is a potentially treatable disorder characterised by seizures and, in some patients, associated with small-cell lung cancer and with other autoantibodies.

TL;DR: This study shows that clinical response to anti-PD-1 immunotherapy in GBM is associated with specific molecular alterations, immune expression signatures, and immune infiltration that reflect the tumor’s clonal evolution during treatment.

TL;DR: This review summarizes the published literature regarding the treatment of newly diagnosed and recurrent meningioma with an emphasis on outcomes stratified by WHO tumor grade, and focuses on patient outcomes following treatment with surgery or radiation therapy.

TL;DR: These guidelines provide recommendations on the diagnosis and management of this group of diseases based on clinical evidence and panel consensus and include expert advice on the management of low-grade infiltrative astrocytomas, oligodendrogliomas, anaplastic gliomas, glioblastomas, medulloblastoma, supratentorial primitive neuroectodermal tumors, and brain metastases.

TL;DR: This comprehensive review confirms the poor outcomes of medical therapy for surgery- and radiation-refractory meningioma and recommends the above PFS-6 benchmarks for future clinical trial design.