J
Jennifer M. Love
Researcher at Auckland City Hospital
Publications - 35
Citations - 2409
Jennifer M. Love is an academic researcher from Auckland City Hospital. The author has contributed to research in topics: Gene & Genome. The author has an hindex of 12, co-authored 35 publications receiving 2361 citations. Previous affiliations of Jennifer M. Love include John Radcliffe Hospital & Massachusetts Institute of Technology.
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Journal ArticleDOI
Genetic analysis of autoimmune type 1 diabetes mellitus in mice.
John A. Todd,T J Aitman,Richard J. Cornall,S Ghosh,Jennifer Ruth Sadler Hall,C M Hearne,Andrew M. Knight,Jennifer M. Love,M A McAleer,Jan-Bas Prins +9 more
TL;DR: In this article, a genetic map of the mouse genome, analysed using the polymerase chain reaction, has been assembled specifically for the study of autoimmune type 1 diabetes in the nonobese diabetic mouse.
Journal ArticleDOI
Towards construction of a high resolution map of the mouse genome using PCR-analysed microsatellites
TL;DR: Fifty sequences from the mouse genome database containing simple sequence repeats or microsatellites have been analysed for size variation using the polymerase chain reaction and gel electrophoresis to facilitate construction of high resolution maps of both the mouse and human genomes.
Journal ArticleDOI
Metastable Pluripotent States in NOD-Mouse-Derived ESCs
Jacob H. Hanna,Styliani Markoulaki,Maisam Mitalipova,Albert W. Cheng,John P. Cassady,Judith Staerk,Bryce W. Carey,Christopher J. Lengner,Ruth K. Foreman,Jennifer M. Love,Qing Gao,Jongpil Kim,Rudolf Jaenisch +12 more
TL;DR: It is found that NOD stem cells can be stabilized by providing constitutive expression of Klf4 or c-Myc or small molecules that can replace these factors during in vitro reprogramming, which suggests that stem cells from different genetic backgrounds can assume distinct states of pluripotency in vitro.
Journal ArticleDOI
The molecular mechanism of phase variation of H. influenzae lipopolysaccharide.
TL;DR: Multiple carbohydrate structures on the outer-membrane lipopolysaccharide (LPS) of the gram-negative pathogen H. influenzae undergo high frequency, reversible loss, indicative of phase variation.
Journal ArticleDOI
Crosses of Nod Mice with the Related Non Strain - a Polygenic Model for Iddm
M A McAleer,Peter C. Reifsnyder,Sheila M Palmer,Michal Prochazka,Jennifer M. Love,James B. Copeman,Elizabeth E. Powell,Nanda R. Rodrigues,Jan-Bas Prins,David V. Serreze,Nicole H. DeLarato,Linda S. Wicker,Laurence B. Peterson,Nicholas J. Schork,John A. Todd,Edward H. Leiter +15 more
TL;DR: This study shows that the diabetogenic phenotype can be achieved through the actions of variable combinations of MHC-unlinked genes and a diabetogenesis MHC haplotype through outcrossing NOD mice to other inbred strains congenic for the NOD M HC haplotype.