J
Jennifer M. Munson
Researcher at Virginia Tech
Publications - 56
Citations - 2041
Jennifer M. Munson is an academic researcher from Virginia Tech. The author has contributed to research in topics: Cancer & Medicine. The author has an hindex of 14, co-authored 43 publications receiving 1273 citations. Previous affiliations of Jennifer M. Munson include Georgia Institute of Technology & École Polytechnique Fédérale de Lausanne.
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Journal ArticleDOI
Functional aspects of meningeal lymphatics in ageing and Alzheimer’s disease
Sandro Da Mesquita,Antoine Louveau,Andrea Vaccari,Igor Smirnov,R. Chase Cornelison,Kathryn M. Kingsmore,Christian Contarino,Christian Contarino,Suna Onengut-Gumuscu,Emily Farber,Daniel M.S. Raper,Daniel M.S. Raper,Kenneth E. Viar,Romie D. Powell,Wendy Baker,Nisha Dabhi,Robin Bai,Rui Cao,Song Hu,Stephen S. Rich,Jennifer M. Munson,Jennifer M. Munson,M. Beatriz S. Lopes,Christopher C. Overall,Scott T. Acton,Jonathan Kipnis +25 more
TL;DR: It is shown that meningeal lymphatic vessels drain macromolecules from the CNS (cerebrospinal and interstitial fluids) into the cervical lymph nodes in mice and improves brain perfusion and learning and memory performance.
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Macrophages: An Inflammatory Link Between Angiogenesis and Lymphangiogenesis.
TL;DR: This review presents macrophages as a cellular link that spatially and temporally connects angiogenesis with lymphangiogenesis, in both physiological growth and in pathological adaptations, such as tumorigenesis.
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Interstitial fluid flow in cancer: implications for disease progression and treatment
TL;DR: The current understanding of the role of interstitial flow in cancer and the tumor microenvironment through cancer progression and therapy is outlined and the current role of fluid flow in the treatment of cancer, including drug transport and therapeutic strategies is discussed.
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Interstitial Flow in a 3D Microenvironment Increases Glioma Invasion by a CXCR4-Dependent Mechanism
TL;DR: In vitro models show that interstitial flow promotes cell invasion in multiple glioma cell lines and CXCR4 was activated in response to flow, which could be responsible for enhanced cell motility, and the new mechanisms ofglioma invasion are significant in therapy to prevent or treat brain cancer invasion.
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Anti-Invasive Adjuvant Therapy with Imipramine Blue Enhances Chemotherapeutic Efficacy Against Glioma
Jennifer M. Munson,Levi Fried,Sydney A. Rowson,Michael Y. Bonner,Lohitash Karumbaiah,Begoña Díaz,Sara A. Courtneidge,Ulla G. Knaus,Daniel J. Brat,Jack L. Arbiser,Jack L. Arbiser,Ravi V. Bellamkonda +11 more
TL;DR: A new anti-invasive small molecule, Imipramine Blue (IB), is reported, which inhibits invasion of glioma in vitro when tested against several models, and is poised for testing in more animal models.