J
Jennifer R. Morgan
Researcher at Marine Biological Laboratory
Publications - 56
Citations - 2344
Jennifer R. Morgan is an academic researcher from Marine Biological Laboratory. The author has contributed to research in topics: Synaptic vesicle & Synaptic vesicle recycling. The author has an hindex of 24, co-authored 50 publications receiving 1987 citations. Previous affiliations of Jennifer R. Morgan include Duke University & University of Texas at Austin.
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Journal ArticleDOI
Sequencing of the sea lamprey (Petromyzon marinus) genome provides insights into vertebrate evolution
J. Joshua Smith,Shigehiro Kuraku,Carson Holt,Tatjana Sauka-Spengler,Ning Jiang,Michael S. Campbell,Mark Yandell,Tereza Manousaki,Axel Meyer,Ona Bloom,Ona Bloom,Jennifer R. Morgan,Joseph D. Buxbaum,Ravi Sachidanandam,Carrie Sims,Alexander S. Garruss,Malcolm Cook,Robb Krumlauf,Leanne M. Wiedemann,Stacia A. Sower,Wayne A. Decatur,Jeffrey A. Hall,Chris T. Amemiya,Nil Ratan Saha,Katherine M. Buckley,Jonathan P. Rast,Sabyasachi Das,Masayuki Hirano,Nathanael McCurley,Peng Guo,Nicolas Rohner,Clifford J. Tabin,Paul Piccinelli,Greg Elgar,Magali Ruffier,Bronwen Aken,Stephen M. J. Searle,Matthieu Muffato,Miguel Pignatelli,Javier Herrero,Matthew Jones,C. Titus Brown,Yu Wen Chung-Davidson,Kaben G. Nanlohy,Scot V. Libants,Chu Yin Yeh,David W. McCauley,James A. Langeland,Zeev Pancer,Bernd Fritzsch,Pieter J. de Jong,Baoli Zhu,Lucinda Fulton,Brenda Theising,Paul Flicek,Marianne E. Bronner,Wesley C. Warren,Sandra W. Clifton,Richard K. Wilson,Weiming Li +59 more
TL;DR: Analyses of the assembly indicate that two whole-genome duplications likely occurred before the divergence of ancestral lamprey and gnathostome lineages, and help define key evolutionary events within vertebrate lineages.
Journal ArticleDOI
A conserved clathrin assembly motif essential for synaptic vesicle endocytosis.
Jennifer R. Morgan,Jennifer R. Morgan,Kondury Prasad,Kondury Prasad,Weihua Hao,George J. Augustine,George J. Augustine,Eileen M. Lafer,Eileen M. Lafer +8 more
TL;DR: It is demonstrated that AP180, like AP-2 and AP-3, binds to the N-terminal domain of clathrin, and sequence analysis reveals a motif, containing the sequence DLL, that exists in multiple copies in manyClathrin APs and indicates that the DLL motif confersclathrin assembly properties to AP180 and AP -2 and, perhaps, to other APs.
Journal ArticleDOI
The Synaptic Vesicle Cycle Revisited: New Insights into the Modes and Mechanisms.
TL;DR: A modern view of the SV life cycle is presented and discusses how neuronal subtype, physiological temperature, and individual activity patterns can recruit different endocytic modes to generate new SVs and sculpt subsequent presynaptic performance.
Journal ArticleDOI
Uncoating of Clathrin-Coated Vesicles in Presynaptic Terminals: Roles for Hsc70 and Auxilin
Jennifer R. Morgan,Jennifer R. Morgan,Kondury Prasad,Kondury Prasad,Suping Jin,George J Augustine,George J Augustine,Eileen M. Lafer,Eileen M. Lafer +8 more
TL;DR: It is established that auxilin and Hsc70 participate in synaptic vesicle recycling in neurons and that an interaction between these proteins is required for CCV uncoating.
Journal ArticleDOI
A Role for the Clathrin Assembly Domain of AP180 in Synaptic Vesicle Endocytosis
Jennifer R. Morgan,Xiaojun Zhao,Mary Womack,Mary Womack,Kondury Prasad,Kondury Prasad,George J. Augustine,George J. Augustine,Eileen M. Lafer,Eileen M. Lafer +9 more
TL;DR: It is concluded that the clathrin assembly domain of AP180 is important for synaptic vesicle recycling at physiological rates of activity and that assembly ofClathrin byAP180 is necessary for maintaining a pool of releasable synaptic vESicles.