J
Jiadong Lin
Researcher at Xi'an Jiaotong University
Publications - 21
Citations - 429
Jiadong Lin is an academic researcher from Xi'an Jiaotong University. The author has contributed to research in topics: Medicine & Biology. The author has an hindex of 5, co-authored 14 publications receiving 121 citations. Previous affiliations of Jiadong Lin include Leiden University.
Papers
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Journal ArticleDOI
Haplotype-resolved diverse human genomes and integrated analysis of structural variation.
Peter Ebert,Peter A. Audano,Qihui Zhu,Bernardo Rodriguez-Martin,David Porubsky,Marc Jan Bonder,Marc Jan Bonder,Arvis Sulovari,Jana Ebler,Weichen Zhou,Rebecca Serra Mari,Feyza Yilmaz,Xuefang Zhao,Xuefang Zhao,PingHsun Hsieh,Joyce V. Lee,Sushant Kumar,Jiadong Lin,Tobias Rausch,Yu Chen,Jingwen Ren,Martin Santamarina,Wolfram Höps,Hufsah Ashraf,Nelson T. Chuang,Xiaofei Yang,Katherine M. Munson,Alexandra P. Lewis,Susan Fairley,Luke J. Tallon,Wayne E. Clarke,Anna O. Basile,Marta Byrska-Bishop,André Corvelo,Uday S. Evani,Tsung Yu Lu,Mark Chaisson,Junjie Chen,Chong Li,Harrison Brand,Harrison Brand,Aaron M. Wenger,Maryam Ghareghani,Maryam Ghareghani,Maryam Ghareghani,William T. Harvey,Benjamin Raeder,Patrick Hasenfeld,Allison A. Regier,Haley J. Abel,Ira M. Hall,Paul Flicek,Oliver Stegle,Oliver Stegle,Mark Gerstein,Jose M. C. Tubio,Zepeng Mu,Yang I. Li,Xinghua Shi,Alex Hastie,Kai Ye,Kai Ye,Zechen Chong,Ashley D. Sanders,Michael C. Zody,Michael E. Talkowski,Michael E. Talkowski,Ryan E. Mills,Scott E. Devine,Charles Lee,Charles Lee,Jan O. Korbel,Tobias Marschall,Evan E. Eichler +73 more
TL;DR: In this article, the authors present 64 assembled haplotypes from 32 diverse human genomes, which integrate all forms of genetic variation, even across complex loci, and identify 107,590 structural variants (SVs), of which 68% were not discovered with short-read sequencing.
Journal ArticleDOI
MSIsensor-pro: Fast, Accurate, and Matched-normal-sample-free Detection of Microsatellite Instability
Peng Jia,Xiaofei Yang,Li Guo,Bowen Liu,Jiadong Lin,Liang Hao,Jianyong Sun,Chengsheng Zhang,Kai Ye +8 more
TL;DR: It is demonstrated that MSIsensor-pro is an ultrafast, accurate, and robust MSI calling method that significantly outperformed the current leading methods in both accuracy and computational cost.
Journal ArticleDOI
Three chromosome-scale Papaver genomes reveal punctuated patchwork evolution of the morphinan and noscapine biosynthesis pathway
Xiaofei Yang,Shenghan Gao,Li Guo,Bo Wang,Yanyan Jia,Jian Zhou,Yizhuo Che,Peng Jia,Jiadong Lin,Jiadong Lin,Tun Xu,Jianyong Sun,Kai Ye +12 more
TL;DR: In this article, a burst of structural variants involving fusions, translocations and duplications within 7.7 million years have assembled nine genes into the benzylisoquinoline alkaloids gene cluster, following a punctuated patchwork model.
Patent
Wearable device and method for intelligent monitoring and early warning of chronic diseases
TL;DR: In this paper, a wearable device and method for intelligent monitoring and early warning of chronic diseases is presented, which includes a wearable equipment terminal, a user mobile terminal and a cloud server.
Journal ArticleDOI
SVision: a deep learning approach to resolve complex structural variants
Jiadong Lin,Songbo Wang,Peter A. Audano,Deyu Meng,Jacob I. Flores,Walter A. Kosters,Xiaofei Yang,Peng Jia,Tobias Marschall,Christine R. Beck,Kai Ye +10 more
TL;DR: In this article , a deep learning-based multi-object recognition framework is proposed to automatically detect and characterize complex structural variants (CSVs) from long-read sequencing data, which can detect both common and previously uncharacterized complex rearrangements.