William T. Harvey

TL;DR: In this article, the authors present 64 assembled haplotypes from 32 diverse human genomes, which integrate all forms of genetic variation, even across complex loci, and identify 107,590 structural variants (SVs), of which 68% were not discovered with short-read sequencing.

TL;DR: In this article, the authors used complementary long-read sequencing technologies to complete the linear assembly of human chromosome 8, including a 2.08-Mb centromeric α-satellite array, a 644-kb copy number polymorphism in the β-defensin gene cluster that is important for disease risk, and an 863-kb variable number tandem repeat at chromosome 8q21.2 that can function as a neocentromere.

TL;DR: A reference-free workflow for diploid de novo genome assembly that combines the chromosome-wide phasing and scaffolding capabilities of single-cell strand sequencing with continuous long-read or high-fidelity sequencing data is described.

TL;DR: This work leverage the chromosome-wide phasing and scaffolding capabilities of single-cell strand sequencing and combine them with high-fidelity (HiFi) long sequencing reads3, in a novel reference-free workflow for diploid de novo genome assembly.

TL;DR: A high-resolution, high-quality bonobo genome assembly was constructed without guidance from reference genomes by applying a multiplatform genomics approach in this paper, where more than 98% of genes are completely annotated and 99% of the gaps are closed.