J
Jingchuan Luo
Researcher at New York University
Publications - 8
Citations - 255
Jingchuan Luo is an academic researcher from New York University. The author has contributed to research in topics: Centromere & Chromosome. The author has an hindex of 4, co-authored 5 publications receiving 179 citations. Previous affiliations of Jingchuan Luo include Johns Hopkins University.
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Journal ArticleDOI
Karyotype engineering by chromosome fusion leads to reproductive isolation in yeast
TL;DR: Overall, budding yeast tolerates a reduction in chromosome number unexpectedly well, providing a striking example of the robustness of genomes to change.
Journal ArticleDOI
Inborn Errors of RNA Lariat Metabolism in Humans with Brainstem Viral Infection
Shen-Ying Zhang,Shen-Ying Zhang,Shen-Ying Zhang,Nathaniel E. Clark,Catherine A. Freije,Elodie Pauwels,Allison J Taggart,Satoshi Okada,Hanna Mandel,Hanna Mandel,Paula Garcia,Michael J. Ciancanelli,Anat Biran,Fabien G. Lafaille,Miyuki Tsumura,Aurélie Cobat,Aurélie Cobat,Jingchuan Luo,Jingchuan Luo,Stefano Volpi,Bastian Zimmer,Sonoko Sakata,Alexandra Dinis,Osamu Ohara,Eduardo J. Garcia Reino,Kerry Dobbs,Mary Hasek,Stephen P. Holloway,Karen McCammon,Stacy A. Hussong,Stacy A. Hussong,Nicholas DeRosa,Candice E. Van Skike,Adam Katolik,Lazaro Lorenzo,Lazaro Lorenzo,Maki Hyodo,Emília Faria,Rabih Halwani,Rie Fukuhara,Gregory A. Smith,Veronica Galvan,Veronica Galvan,Masad J. Damha,Saleh Al-Muhsen,Yuval Itan,Yuval Itan,Jef D. Boeke,Jef D. Boeke,Luigi D. Notarangelo,Lorenz Studer,Masao Kobayashi,Luísa Diogo,William G. Fairbrother,Laurent Abel,Laurent Abel,Laurent Abel,Brad R. Rosenberg,Brad R. Rosenberg,P. John Hart,P. John Hart,Amos Etzioni,Amos Etzioni,Jean-Laurent Casanova +63 more
TL;DR: Autosomal recessive, partial DBR1 deficiency underlies viral infection of the brainstem in humans through the disruption of tissue-specific and cell-intrinsic immunity to viruses.
Journal ArticleDOI
RADOM, an efficient in vivo method for assembling designed DNA fragments up to 10 kb long in Saccharomyces cerevisiae.
Lin Qiuhui,Bin Jia,Leslie A. Mitchell,Leslie A. Mitchell,Jingchuan Luo,Jingchuan Luo,Kun Yang,Kun Yang,Karen I. Zeller,Zhang Wenqian,Zhuwei Xu,Zhuwei Xu,Giovanni Stracquadanio,Joel S. Bader,Jef D. Boeke,Jef D. Boeke,Ying-Jin Yuan +16 more
TL;DR: RADOM is described, an improved assembly method via homologous recombination in Saccharomyces cerevisiae, which combines assembly in yeasto with blue/white screening in Escherichia coli and can successfully assemble ∼3 and ∼10 kb DNA fragments that are highly similar to the yeast genome rapidly and accurately.
Journal ArticleDOI
BioPartsBuilder: A synthetic biology tool for combinatorial assembly of biological parts
TL;DR: BioPartsBuilder is developed as a biologist-friendly web tool to design biological parts that are compatible with DNA combinatorial assembly methods, such as Golden Gate and related methods, and retrieves biological sequences, enforces compliance with assembly design standards and provides a fabrication plan for each fragment.
Posted ContentDOI
Synthetic chromosome fusion: effects on genome structure and function
Jingchuan Luo,Guillaume Mercy,Luis A. Vale-Silva,Xiaoji Sun,Neta Agmon,Weimin Zhang,Yang K,Stracquadanio G,Agnès Thierry,Ahn Jy,Adoff G,Andrew R. D’Avino,Henri Berger,Yun-Ching Chen,Chickering M,Fishman O,Greeno Rv,SangMin Kim,Hong Seo Lim,Im J,Meyer L,Anna J. Moyer,Surekha Mullangi,Natalie A. Murphy,Natov P,Nimer M,Radley A,Tripathy A,Tony L. Wang,Wilkerson N,Zheng T,Zhou,Kaback Db,Joel S. Bader,Leslie A. Mitchell,Julien Mozziconacci,Andreas Hochwagen,Romain Koszul,Jef D. Boeke +38 more
TL;DR: These fusion chromosomes were used to show that axial element Red 1 binding in meiosis is not strictly chromosome size dependent even though Red1 binding is enriched on the three smallest chromosomes in wild-type yeast, and to discover an unexpected role for centromeres in Red1binding patterns.