J
Johan Ankarklev
Researcher at Stockholm University
Publications - 30
Citations - 1669
Johan Ankarklev is an academic researcher from Stockholm University. The author has contributed to research in topics: Gene & Giardia. The author has an hindex of 13, co-authored 22 publications receiving 1371 citations. Previous affiliations of Johan Ankarklev include Uppsala University & Karolinska Institutet.
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Journal ArticleDOI
Behind the smile: cell biology and disease mechanisms of Giardia species.
TL;DR: This Review discusses recent discoveries in the molecular cell biology and pathogenesis of G. intestinalis and suggests that the disease mechanisms are still poorly understood.
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Draft Genome Sequencing of Giardia intestinalis Assemblage B Isolate GS: Is Human Giardiasis Caused by Two Different Species?
Oscar Franzén,Jon Jerlström-Hultqvist,Elsie Castro,Ellen Sherwood,Johan Ankarklev,David S. Reiner,Daniel Palm,Jan Andersson,Björn Andersson,Staffan G. Svärd +9 more
TL;DR: The genomic differences between WB and GS may explain some of the observed biological and clinical differences between the two isolates, and it suggests that assemblage A and B Giardia can be two different species.
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Infected erythrocyte-derived extracellular vesicles alter vascular function via regulatory Ago2-miRNA complexes in malaria
Pierre-Yves Mantel,Daisy Hjelmqvist,Michael Walch,Solange Kharoubi-Hess,Sandra K. Nilsson,Deepali Ravel,Marina Ribeiro,Christof Grüring,Siyuan Ma,Prasad K. Padmanabhan,Alexander J. Trachtenberg,Johan Ankarklev,Nicolas M. B. Brancucci,Nicolas M. B. Brancucci,Curtis Huttenhower,Manoj T. Duraisingh,Ionita Ghiran,Winston Patrick Kuo,Luis Filgueira,Roberta Martinelli,Matthias Marti,Matthias Marti +21 more
TL;DR: These findings provide a mechanistic link between EVs and vascular dysfunction during malaria infection and show that EVs are efficiently internalized by endothelial cells, where the miRNA-Argonaute 2 complexes modulate target gene expression and barrier properties.
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Genome analysis and comparative genomics of a Giardia intestinalis assemblage E isolate
Jon Jerlström-Hultqvist,Oscar Franzén,Oscar Franzén,Johan Ankarklev,Feifei Xu,Eva Nohýnková,Jan Andersson,Staffan G. Svärd,Björn Andersson,Björn Andersson +9 more
TL;DR: Compared genomics of the three diverse Giardia intestinalis isolates P15, GS and WB to define a core proteome for this species complex and to identify lineage-specific genes were used to identify novel members of the VSP, NEK Kinase and HCMP gene families.
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Seroepidemiology of human Toxoplasma gondii infection in China
Yue Xiao,Jigang Yin,Ning Jiang,Mei Xiang,Lili Hao,Huijun Lu,Hong Sang,Xian-ying Liu,Huiji Xu,Johan Ankarklev,Johan Lindh,Qijun Chen,Qijun Chen +12 more
TL;DR: Results suggest that women are more exposed to T. gondii infection than men in China and argue for deeper investigations for the potential risk factors that threat the female populations.