J
Jonathan D. Dinman
Researcher at University of Maryland, College Park
Publications - 166
Citations - 8337
Jonathan D. Dinman is an academic researcher from University of Maryland, College Park. The author has contributed to research in topics: Translational frameshift & Ribosome. The author has an hindex of 52, co-authored 158 publications receiving 7404 citations. Previous affiliations of Jonathan D. Dinman include University of Maryland, Baltimore & Medical University of South Carolina.
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Journal ArticleDOI
A new system for naming ribosomal proteins
Nenad Ban,Roland Beckmann,Jamie H. D. Cate,Jonathan D. Dinman,François Dragon,Steven R. Ellis,Denis L. J. Lafontaine,Lasse Lindahl,Anders Liljas,Jeffrey M. Lipton,Michael A. McAlear,Peter B. Moore,Harry F. Noller,Joaquin Ortega,Vikram Govind Panse,Venki Ramakrishnan,Christian M. T. Spahn,Thomas A. Steitz,Marek Tchórzewski,David Tollervey,Alan J. Warren,James R. Williamson,Daniel N. Wilson,Ada Yonath,Marat Yusupov +24 more
TL;DR: A system for naming ribosomal proteins is described, designed so that new names are similar enough to old names to be easily recognized, but are written in a format that unambiguously identifies them as 'new system' names.
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A -1 ribosomal frameshift in a double-stranded RNA virus of yeast forms a gag-pol fusion protein.
TL;DR: Analysis of the "slippery site" suggests that a low probability of unpairing of the aminoacyl-tRNA from the 0-frame codon at the ribosomal A site reduces the efficiency of frameshifting more than the reluctance of a given tRNA to have its wobble base mispaired.
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rRNA pseudouridylation defects affect ribosomal ligand binding and translational fidelity from yeast to human cells.
Karen Jack,Cristian Bellodi,Dori M. Landry,Rachel O. Niederer,Arturas Meskauskas,Arturas Meskauskas,Sharmishtha Musalgaonkar,Noam Kopmar,Olya Krasnykh,Alison M. Dean,Sunnie R. Thompson,Davide Ruggero,Jonathan D. Dinman +12 more
TL;DR: Describing ribosomes isolated from a yeast strain in which Cbf5p, the yeast homolog of DKC1, is catalytically impaired through a D95A mutation reveals specific roles for Ψ modification in ribosome-ligand interactions that are conserved in yeast, mouse, and humans.
Journal ArticleDOI
Ribosomal frameshifting efficiency and gag/gag-pol ratio are critical for yeast M1 double-stranded RNA virus propagation.
TL;DR: In this paper, the importance of frameshifting efficiency for viral propagation was tested in a system where the M1 (killer toxin-encoding) satellite RNA is supported by a full-length L-A cDNA clone.
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Trajectories of the ribosome as a Brownian nanomachine.
Ali Dashti,Peter Schwander,Robert Langlois,R. Fung,Wen Li,Ahmad Hosseinizadeh,Hstau Y. Liao,Jesper Pallesen,Gyanesh Sharma,Vera A. Stupina,Anne E. Simon,Jonathan D. Dinman,Joachim Frank,Abbas Ourmazd +13 more
TL;DR: This work presents a new analytical approach capable of determining the free-energy landscape and the continuous trajectories of molecular machines from a large number of snapshots obtained by cryogenic electron microscopy and allows model-free quantitative analysis of the degrees of freedom and the energy landscape underlying continuous conformational changes in nanomachines, including those important for biological function.