J
Jonathan J. Ewbank
Researcher at Aix-Marseille University
Publications - 108
Citations - 9458
Jonathan J. Ewbank is an academic researcher from Aix-Marseille University. The author has contributed to research in topics: Innate immune system & Caenorhabditis elegans. The author has an hindex of 46, co-authored 107 publications receiving 8659 citations. Previous affiliations of Jonathan J. Ewbank include Laboratory of Molecular Biology & University of the Mediterranean.
Papers
More filters
Journal ArticleDOI
Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita
Pierre Abad,Pierre Abad,Jérôme Gouzy,Jean-Marc Aury,Jean-Marc Aury,Philippe Castagnone-Sereno,Philippe Castagnone-Sereno,Etienne Danchin,Etienne Danchin,Emeline Deleury,Emeline Deleury,Laetitia Perfus-Barbeoch,Laetitia Perfus-Barbeoch,Véronique Anthouard,Véronique Anthouard,François Artiguenave,François Artiguenave,Vivian C. Blok,Marie-Cécile Caillaud,Marie-Cécile Caillaud,Pedro M. Coutinho,Corinne Dasilva,Corinne Dasilva,Francesca De Luca,Florence Deau,Florence Deau,Magali Esquibet,Timothé Flutre,Jared V. Goldstone,Noureddine Hamamouch,Tarek Hewezi,Olivier Jaillon,Olivier Jaillon,Claire Jubin,Claire Jubin,Paola Leonetti,Marc Magliano,Marc Magliano,Tom R. Maier,Gabriel V. Markov,Paul McVeigh,Graziano Pesole,Julie Poulain,Julie Poulain,Marc Robinson-Rechavi,Marc Robinson-Rechavi,Erika Sallet,Béatrice Ségurens,Béatrice Ségurens,Delphine Steinbach,T.O.G. Tytgat,Edgardo Ugarte,Edgardo Ugarte,Cyril Van Ghelder,Cyril Van Ghelder,Pasqua Veronico,Thomas J. Baum,Mark Blaxter,Teresa Bleve-Zacheo,Eric L. Davis,Jonathan J. Ewbank,Bruno Favery,Bruno Favery,Eric Grenier,Bernard Henrissat,John T. Jones,Vincent Laudet,Aaron G. Maule,Hadi Quesneville,Marie-Noëlle Rosso,Marie-Noëlle Rosso,Thomas Schiex,Geert Smant,Jean Weissenbach,Jean Weissenbach,Patrick Wincker,Patrick Wincker +76 more
TL;DR: The draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, is reported, providing insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.
Journal ArticleDOI
TLR-independent control of innate immunity in Caenorhabditis elegans by the TIR domain adaptor protein TIR-1, an ortholog of human SARM.
Carole Couillault,Nathalie Pujol,Jérôme Reboul,Laurence Sabatier,Jean-François Guichou,Yuji Kohara,Jonathan J. Ewbank +6 more
TL;DR: It is shown that the small GTPase Rab1 and the f subunit of ATP synthase participate specifically in the control of antimicrobial peptide gene expression, and TIR-1 may represent a component of a previously uncharacterized, but conserved, innate immune signaling pathway.
Journal ArticleDOI
Inducible Antibacterial Defense System in C. elegans
Gustavo V. Mallo,C. Léopold Kurz,Carole Couillault,Nathalie Pujol,Samuel Granjeaud,Yuji Kohara,Jonathan J. Ewbank +6 more
TL;DR: It is shown here that infection of C. elegans by the Gram-negative bacterium Serratia marcescens provokes a marked upregulation of the expression of many genes, leading to the first demonstration of inducible antibacterial defenses in the nematode Caenorhabditis elegans.
Journal ArticleDOI
A reverse genetic analysis of components of the Toll signaling pathway in Caenorhabditis elegans.
Nathalie Pujol,Elizabeth M Link,Leo X. Liu,C. Léopold Kurz,Geneviève Alloing,Man-Wah Tan,Keith P. Ray,Roberto Solari,Carl D. Johnson,Jonathan J. Ewbank +9 more
TL;DR: In C. elegans, tol-1 is important for development and pathogen recognition, as is Toll in Drosophila, but remarkably for the latter rôle, it functions in the context of a behavioral mechanism that keeps worms away from potential danger.
Journal ArticleDOI
Detection and avoidance of a natural product from the pathogenic bacterium Serratia marcescens by Caenorhabditis elegans
Elizabeth Pradel,Yun Zhang,Nathalie Pujol,Tohey Matsuyama,Cornelia I. Bargmann,Jonathan J. Ewbank +5 more
TL;DR: By combining bacterial genetics and nematode genetics, it is shown that C. elegans specifically avoids certain strains of Serratia based on their production of the cyclic lipodepsipentapeptide serrawettin W2.