J
Jordan Safirstein
Researcher at Catholic Medical Center
Publications - 11
Citations - 518
Jordan Safirstein is an academic researcher from Catholic Medical Center. The author has contributed to research in topics: Peripartum cardiomyopathy & Dilated cardiomyopathy. The author has an hindex of 5, co-authored 10 publications receiving 376 citations.
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Journal ArticleDOI
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies
James S. Ware,Jian Li,Erica Mazaika,Christopher M Yasso,Tiffany DeSouza,Thomas P. Cappola,Emily J. Tsai,Denise Hilfiker-Kleiner,Chizuko Kamiya,Francesco Mazzarotto,Stuart A. Cook,Indrani Halder,Sanjay K Prasad,Jessica Pisarcik,Karen Hanley-Yanez,Rami Alharethi,Julie B. Damp,Eileen Hsich,Uri Elkayam,Richard Sheppard,Angela Kealey,Jeffrey D. Alexis,Gautam V. Ramani,Jordan Safirstein,John P. Boehmer,Daniel F. Pauly,Ilan S. Wittstein,Vinay Thohan,Mark J. Zucker,Peter Liu,John Gorcsan,Dennis M. McNamara,Christine E. Seidman,Jonathan G. Seidman,Jonathan G. Seidman,Zoltan Arany +35 more
TL;DR: TTN truncating variants were the most prevalent genetic predisposition in each disorder and were significantly correlated with a lower ejection fraction at 1-year follow-up.
Journal ArticleDOI
Evaluation of the clinical relevance of baseline left ventricular ejection fraction as a predictor of recovery or persistence of severe dysfunction in women in the United States with peripartum cardiomyopathy.
Sorel Goland,Fahed Bitar,Kalgi Modi,Jordan Safirstein,Angela S. Ro,James Mirocha,Nudrat Khatri,Uri Elkayam +7 more
TL;DR: Baseline LVEF however, has a limited sensitivity for prediction of failure to improve in individual patients and can not be used as an indication for premature use of aggressive therapy including devices or cardiac transplantation.
Journal ArticleDOI
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies
James S. Ware,Jian Li,Erica Mazaika,Christopher M Yasso,Tiffany DeSouza,Thomas P. Cappola,Emily J. Tsai,Denise Hilfiker-Kleiner,Chizuko Kamiya,Francesco Mazzarotto,Stuart A. Cook,Indrani Halder,Sanjay K Prasad,Jessica Pisarcik,Karen Hanley-Yanez,Rami Alharethi,Julie B. Damp,Eileen Hsich,Uri Elkayam,Richard Sheppard,Angela Kealey,Jeffrey D. Alexis,Gautam V. Ramani,Jordan Safirstein,John P. Boehmer,Daniel F. Pauly,Ilan S. Wittstein,Vinay Thohan,Mark J. Zucker,Peter Liu,John Gorcsan,Dennis M. McNamara,Christine E. Seidman,Jonathan G. Seidman,Zoltan Arany +34 more
TL;DR: In this article, the authors compared the prevalence of different variant types (nonsense, frameshift, and splicing) in women with peripartum cardiomyopathy and with population controls, and found that truncating variants were the most prevalent genetic predisposition in each disorder.
Journal ArticleDOI
Cardiac epithelioid hemangioendothelioma with 8-year follow-up
TL;DR: An incidentally discovered right atrial mass excised from the heart of a 51-year-old woman was found on pathological examination to be an epithelioid hemangioendothelioma, the first report on the behavior of this distinctive vascular neoplasm occurring as an isolated cardiac tumor.
Journal ArticleDOI
Circulating T-Cell Subsets, Monocytes, and Natural Killer Cells in Peripartum Cardiomyopathy: Results From the Multicenter IPAC Study.
Charles F. McTiernan,Penelope A. Morel,Leslie T. Cooper,Navin Rajagopalan,Vinay Thohan,Mark J. Zucker,John P. Boehmer,Biykem Bozkurt,Paul J. Mather,Thornton Jb,Jalal K. Ghali,Karen Hanley-Yanez,James D. Fett,Indrani Halder,Dennis M. McNamara,James D. Fett,Jessica Pisarcik,Charles F. McTiernan,John Gorcsan,Erik B. Schelbert,Rami Alharethi,Kismet Rasmusson,Kim Brunisholz,Amy Butler,Deborah Budge,A.G. Kfoury,Benjamin D. Horne,Joe Tuinei,Heather Brown,Julie B. Damp,Allen J. Naftilan,Jill Russell,Darla Freehardt,Eileen Hsich,Cynthia Oblak,Greg Ewald,Donna Whitehead,Jean Flanagan,Anne E. Platts,Uri Elkayam,Jorge Caro,Stephanie Mullin,Michael M. Givertz,M. Susan Anello,David C. Booth,Tiffany Sandlin,Wendy Wijesiri,Lori A. Blauwet,Joann Brunner,Mary A. Phelps,Ruth Kempf,Kalgi Modi,Tracy Norwood,Joan Briller,Decebal Sorin Griza,G. Michael Felker,Robb D. Kociol,Patricia A. Adams,Gretchen L. Wells,Deborah Wesley-Farrington,Sandra Soots,Richard Sheppard,Caroline Michel,Nathalie Lapointe,Heather Nathaniel,Angela Kealey,Marc J. Semigran,Maureen Daher,David H. Silber,Eric Popjes,Patricia Frey,Todd Nicklas,Jeffrey D. Alexis,Lori Caufield,John W. Thornton,Mindy Gentry,Vincent J.B. Robinson,Gyanendra Sharma,Joan Holloway,Maria Powell,David W. Markham,Mark H. Drazner,Lynn Fernandez,David A. Baran,Martin L. Gimovsky,Natalia Hochbaum,Bharati Patel,Laura Adams,Gautam V. Ramani,Stephen S. Gottlieb,Shawn Robinson,Stacy Fisher,Joanne Marshall,Jennifer Haythe,Donna Mancini,Rachel Bijou,Maryjane Farr,Marybeth Marks,Henry Arango,Mariana Bolos,Sharon Rubin,Raphael Bonita,Susan Eberwine,Hal Skopicki,Kathleen Stergiopoulos,Ellen McCathy-Santoro,Jennifer Intravaia,Elizabeth Maas,Jordan Safirstein,Audrey Kleet,Nancy Martinez,Christine Corpoin,Donna Hesari,Sandra Chaparro,Laura J. Hudson,Zora Injic,Ilan S. Wittstein +116 more
TL;DR: Compared with HP control women, early postpartum PPCM women show significantly reduced NK cells, and higher CD3+CD4-CD8-CD38+ cells, which both normalize over time post partum.