D
Dennis M. McNamara
Researcher at University of Pittsburgh
Publications - 203
Citations - 8923
Dennis M. McNamara is an academic researcher from University of Pittsburgh. The author has contributed to research in topics: Heart failure & Transplantation. The author has an hindex of 47, co-authored 191 publications receiving 7640 citations. Previous affiliations of Dennis M. McNamara include Harvard University.
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Journal ArticleDOI
Controlled trial of intravenous immune globulin in recent-onset dilated cardiomyopathy
Dennis M. McNamara,Richard Holubkov,Randall C. Starling,G. William Dec,Evan Loh,Guillermo Torre-Amione,Alan Gass,Karen Janosko,Tammy Tokarczyk,Paul D. Kessler,Douglas L. Mann,Arthur M. Feldman +11 more
TL;DR: It is suggested that for patients with recent-onset dilated cardiomyopathy, IVIG does not augment the improvement in LVEF, however, in this overall cohort, LVEf improved significantly during follow-up, and the short-term prognosis remains favorable.
Journal ArticleDOI
Current Diagnostic and Treatment Strategies for Specific Dilated Cardiomyopathies: A Scientific Statement From the American Heart Association.
Biykem Bozkurt,Monica Colvin,Jennifer L. Cook,Leslie T. Cooper,Anita Deswal,Gregg C. Fonarow,Gary S. Francis,Daniel J. Lenihan,Eldrin F. Lewis,Dennis M. McNamara,Elfriede Pahl,Ramachandran S. Vasan,Kumudha Ramasubbu,Kismet Rasmusson,Jeffrey A. Towbin,Clyde W. Yancy +15 more
TL;DR: The intent of this American Heart Association (AHA) scientific statement is to summarize the current understanding of dilated cardiomyopathies, with special emphasis on recent developments in diagnostic approaches and therapies for specific cardiologyopathies.
Journal ArticleDOI
Mutation in glycerol-3-phosphate dehydrogenase 1 like gene (GPD1-L) decreases cardiac Na+ current and causes inherited arrhythmias
Barry London,Michael Michalec,Haider Mehdi,Xiaodong Zhu,Laurie J. Kerchner,Shamarendra Sanyal,Prakash C. Viswanathan,Arnold E. Pfahnl,Lijuan L. Shang,Mohan Madhusudanan,Catherine J. Baty,Stephen M. Lagana,Ryan G. Aleong,Rebecca Gutmann,Michael J. Ackerman,Dennis M. McNamara,Raul Weiss,Samuel C. Dudley +17 more
TL;DR: GPD1-L is a novel gene that may affect trafficking of the cardiac Na+ channel to the cell surface that causes Brugada syndrome and is identified through direct sequencing.
Journal ArticleDOI
Shared Genetic Predisposition in Peripartum and Dilated Cardiomyopathies
James S. Ware,Jian Li,Erica Mazaika,Christopher M Yasso,Tiffany DeSouza,Thomas P. Cappola,Emily J. Tsai,Denise Hilfiker-Kleiner,Chizuko Kamiya,Francesco Mazzarotto,Stuart A. Cook,Indrani Halder,Sanjay K Prasad,Jessica Pisarcik,Karen Hanley-Yanez,Rami Alharethi,Julie B. Damp,Eileen Hsich,Uri Elkayam,Richard Sheppard,Angela Kealey,Jeffrey D. Alexis,Gautam V. Ramani,Jordan Safirstein,John P. Boehmer,Daniel F. Pauly,Ilan S. Wittstein,Vinay Thohan,Mark J. Zucker,Peter Liu,John Gorcsan,Dennis M. McNamara,Christine E. Seidman,Jonathan G. Seidman,Jonathan G. Seidman,Zoltan Arany +35 more
TL;DR: TTN truncating variants were the most prevalent genetic predisposition in each disorder and were significantly correlated with a lower ejection fraction at 1-year follow-up.
Journal ArticleDOI
Clinical Outcomes for Peripartum Cardiomyopathy in North America Results of the IPAC Study (Investigations of Pregnancy-Associated Cardiomyopathy)
Dennis M. McNamara,Uri Elkayam,Rami Alharethi,Julie B. Damp,Eileen Hsich,Gregory A. Ewald,Kalgi Modi,Jeffrey D. Alexis,Gautam V. Ramani,Marc J. Semigran,Jennifer Haythe,David W. Markham,Josef Marek,John Gorcsan,Wen Chi Wu,Yan Lin,Indrani Halder,Jessica Pisarcik,Leslie T. Cooper,James D. Fett +19 more
TL;DR: In a prospective cohort with PPCM, most women recovered; however, 13% had major events or persistent severe cardiomyopathy, and severe LV dysfunction and greater remodeling at study entry were associated with less recovery.